Plastic-based multilayer packaging has an important function on the packaging market, but is currently not recyclable as the polymer layers used are usually thermodynamically immiscible. This work therefore follows the approach to prepare separable multilayer packaging using a packaging adhesive modified with thermally unstable adducts, and proposes a corresponding recycling process. For this purpose, typical multilayer structures (polyethylene (PE)// polyethylene terephtalate (PET), PET//aluminum, and PE//aluminum) were prepared by curing furan-/maleimide-functionalized polyurethane (PU)-prepolymers with a three-functional cross-linking agent. Adhesions of up to over 3N per 15 mm test specimen were measured or substrate failures of PET films were observed. However, heating in dimethylsulfoxide, the retro-Diels–Alder reaction takes place and the cross-linked adhesive turns thermoplastic and dissolves in the solvent. Thus, the laminate separates and the pure PE, PET, and aluminum foils can be recovered without any PU residue. 相似文献
In this paper, we study the influence of innovator roles in highly innovative ventures. In order to obtain a differentiated picture we take into account the degree of innovativeness as a moderating variable. To test our hypotheses we use a sample of 146 highly innovative new product development projects. We choose a rigorous sampling design and apply state‐of‐the‐art measures for the degree of innovativeness. Furthermore, we apply multi‐trait‐multi‐method methodology (MTMM) to enhance the validity of our study. The results show that innovator roles have a strong influence on innovation success but these influences are positively and negatively moderated by innovativeness. The moderating influences depend on the type of innovativeness. Remarkably, with increasing technological innovativeness innovator roles which create inter‐organizational links with the outside world appear to be more important than intra‐organizational linker roles, and support from high‐ranked organizational members turns out to have a significant negative effect on project success with higher degrees of technological innovativeness. Possible explanations for these findings are discussed and consequences for innovation research and innovation management are shown. 相似文献
Plumbagin is a plant-derived naphthoquinone that is widely used in traditional Asian medicine due to its anti-inflammatory and anti-microbial properties. Additionally, plumbagin is cytotoxic for cancer cells due to its ability to trigger reactive oxygen species (ROS) formation and subsequent apoptosis. Since it was reported that plumbagin may inhibit the differentiation of bone resorbing osteoclasts in cancer-related models, we wanted to elucidate whether plumbagin interferes with cytokine-induced osteoclastogenesis. Using C57BL/6 mice, we unexpectedly found that plumbagin treatment enhanced osteoclast formation and that this effect was most pronounced when cells were pre-treated for 24 h with plumbagin before subsequent M-CSF/RANKL stimulation. Plumbagin caused a fast induction of NFATc1 signalling and mTOR-dependent activation of p70S6 kinase which resulted in the initiation of protein translation. In line with this finding, we observed an increase in RANK surface expression after Plumbagin stimulation that enhanced the responsiveness for subsequent RANKL treatment. However, in Balb/c mice and Balb/c-derived RAW264.7 macrophages, these findings could not be corroborated and osteoclastogenesis was inhibited. Our results suggest that the effects of plumbagin depend on the model system used and can therefore either trigger or inhibit osteoclast formation. 相似文献
The chemical vapor deposition method was used to deposit thin films of cobalt oxide starting with cobalt (II) acetylacetonate and oxygen. The deposition process was investigated and the obtained films were identified as a cubic spinel-type polycrystalline Co3O4 with a crystallite size of 30–40 nm. The coating was carbon-free and the surface oxygen concentration was measured to be 66 at.% with AES analysis. Smooth and highly uniform thin films were deposited on planar stainless steel substrates and subjected to TPR and catalysis tests that show positive correlation. The apparent activation energy of Co3O4 reduction to CoO was measured to be (33±5) kJ/mol. The catalytic activity of Co3O4 was investigated toward the conversion of both propane and ethanol to carbon dioxide. Though the catalytic action was registered at the same temperature, the deactivation process was seen to be different. The catalytic conversion of ethanol induces a fast deactivation process, which was linked to its high ability to reduce Co3O4. 相似文献
A key component of a hydrogen fuel cell is a catalyst to dissociate dihydrogen to hydrogen atoms. In the present study, the adsorption of hydrogen on Pt/C fuel cell catalysts has been investigated by inelastic neutron scattering spectroscopy.
Monitoring a clean Pt(50%)/C catalyst with low energy neutron spectroscopy, after exposure to dihydrogen at 20 K, as it was heated to room temperature, showed three distinct temperature regimes: (i) a decrease in intensity from 10 to 60 K, (ii) a rise to a maximum between 60 and 120 K and then (iii) a slow fall-off towards room temperature. We assign the three regions as: (i) desorption of physisorbed dihydrogen, (ii) dissociation of dihydrogen to give an adsorbed layer and (iii) damping of the response by an increasing Debye–Waller factor.
The vibrational INS spectra of a series of Pt/C catalysts prepared under varying conditions were similar indicating that the same types of site are common to all the catalysts, although the relative proportions of each site are sample dependent. Features at 520, 950 and part of the intensity at 1300 cm−1 are assigned to hydrogen on (1 1 1) faces, in good agreement with single crystal data. The mode at 640 cm−1 is assigned as the doubly degenerate asymmetric stretch of Pt(1 0 0) faces with the symmetric stretch near 550 cm−1.
We assign the bending mode of the on-top site to the feature at 470 cm−1. The Pt–H stretch mode was observed at 2079 cm−1. This is a significant result: this is the first time that hydrogen on the on-top sites has been observed on nanosized platinum particles supported on high surface area carbon black. The width of the INS peak is surprisingly large and may give additional information on the type and relative proportions of the crystallographic faces present on the catalyst particles. 相似文献
One of the elementary prerequisites for medical research on and with humans is the patients’ or probands’ informed consent. To ensure informed consent, study participants must be—among other things—provided with high-quality information. We developed criteria to assess and evaluate the quality of various written patient information material.
Methods
Based on a catalogue addressing 117 single criteria, we assessed the quality of 128 randomly selected documents from study proposals submitted to the ethical committee of Luebeck University in 2006. Each criterion refers to one of six quality areas (such as “readability and comprehensibility” or “potential benefit and harm”).
Results
The documents on average satisfied half of the criteria with a range from 20–76% for single items. The area with the highest quality score was “consent form” (64%), while “potential benefit and harm” (35%) was the lowest. Material from drug trials showed a significantly higher quality than that from other study types. Only 21 out of 117 criteria were met in more than 80% of all relevant documents.
Conclusion
The study provides evidence for significant deficits in the information material from basic and clinical research projects presented to one academic research ethics committee. Researchers need support in developing and writing informed consent documents. Our set of criteria could be used to make them more sensitive to the various demands involved. 相似文献
Parallel and distributed methods for evolutionary algorithms have concentrated on maintaining multiple populations of genotypes,
where each genotype in a population encodes a potential solution to the problem. In this paper, we investigate the parallelisation
of the genotype itself into a collection of independent chromosomes which can be evaluated in parallel. We call this multi-chromosomal evolution
(MCE). We test this approach using Cartesian Genetic Programming and apply MCE to a series of digital circuit design problems
to compare the efficacy of MCE with a conventional single chromosome approach (SCE). MCE can be readily used for many digital
circuits because they have multiple outputs. In MCE, an independent chromosome is assigned to each output. When we compare
MCE with SCE we find that MCE allows us to evolve solutions much faster. In addition, in some cases we were able to evolve
solutions with MCE that we unable to with SCE. In a case-study, we investigate how MCE can be applied to to a single objective
problem in the domain of image classification, namely, the classification of breast X-rays for cancer. To apply MCE to this
problem, we identify regions of interest (RoI) from the mammograms, divide the RoI into a collection of sub-images and use
a chromosome to classify each sub-image. This problem allows us to evaluate various evolutionary mutation operators which
can pairwise swap chromosomes either randomly or topographically or reuse chromosomes in place of other chromosomes. 相似文献
Calcium cobaltite Ca3Co4−xO9+δ (CCO) is a promising p-type thermoelectric (TE) material for high-temperature applications in air. The grains of the material exhibit strong anisotropic properties, making texturing and nanostructuring mostly favored to improve thermoelectric performance. On the one hand multitude of interfaces are needed within the bulk material to create reflecting surfaces that can lower the thermal conductivity. On the other hand, low residual porosity is needed to improve the contact between grains and raise the electrical conductivity. In this study, CCO fibers with 100% flat cross sections in a stacked, compact form are electrospun. Then the grains within the nanoribbons in the plane of the fibers are grown. Finally, the nanoribbons are electrospun into a textured ceramic that features simultaneously a high electrical conductivity of 177 S cm−1 and an immensely enhanced Seebeck coefficient of 200 µV K−1 at 1073 K are assembled. The power factor of 4.68 µW cm−1 K−2 at 1073 K in air surpasses all previous CCO TE performances of nanofiber ceramics by a factor of two. Given the relatively high power factor combined with low thermal conductivity, a relatively large figure-of-merit of 0.3 at 873 K in the air for the textured nanoribbon ceramic is obtained. 相似文献