A 500-MHz 4-Mb CMOS pipeline-burst cache SRAM with point-to-pointnoise reduction coding I/O

A 32-b 500-MHz 4-1-1-1 operation 4-Mb pipeline burst cache SRAM has been developed. In order to achieve both high bandwidth operation and short latency operation, we developed the following technologies: 1) a prefetched pipeline-burst scheme with double late-write buffers, 2) gate size reduction and a bit-line equalization by source resetting, 3) point-to-point bidirectional coding I/O's to reduce bus noise and power consumption, and 4) a three-level metal 0.25-μm CMOS process technology with six transistor memory cells     

Temperature dependence of signal gain in Er3+-dopedoptical fiber amplifiers

Temperature-dependent signal gain characteristics at signal wavelengths of 1.536 and 1.552 μm in Er³⁺-doped optical fibers with a temperature range of -40 to 80°C are reported for 0.98 and 1.48 μm pumping. The temperature dependences of signal gain strongly depend on fiber length, pump wavelength, and signal wavelength. The fiber length at which signal gain temperature insensitivity occurs is found for the amplification of a 0.98-μm-pump-1.536-μm-signal, a 0.98-μm-pump-1.552-μm-signal, and a 1.48-μm-pump-1.536-μm-signal. It is confirmed theoretically that the temperature dependences result from linear changes in the fluorescence, and absorption cross sections at the signal and pump wavelengths, and a shift in the effective pump wavelength     

Highly efficient configuration of a Pr3+-doped fluoridefiber amplifier module with an optical circulator

A highly efficient Pr³⁺-doped fluoride fiber amplifier configuration with an optical circulator, in which the input signal light is amplified both forward and backward through a Pr³⁺-doped fluoride fiber, is investigated with a view to decreasing the drive current and improving the reliability of pump laser diodes (LD's). With this double-path configuration, a 25-dB signal gain is achieved at an LD drive current of 110 mA. This LD drive current is about half that needed for a conventional single-path configuration. It is also found that this double-path configuration provides a double-gain coefficient, a slightly low saturation power, and a slightly narrow spectral gain width     

Noise characteristics of Er3+-doped fiber amplifierspumped by 0.98 and 1.48 μm laser diodes

Measured noise characteristics of Er³⁺-doped optical fiber amplifiers pumped by 0.98- and 1.48-μm laser diodes (LDs) are reported. The noise figures estimated from the beat noise between signal and spontaneous emission are 3.2 dB for pumping by 0.98-μm LD and 4.1 dB for pumping by 1.48-μm LD. The beat noise between spontaneous emission components and the spontaneous shot noise for the 0.98-μm pumping are lower than those for the 1.48-μm pumping     

2.5 Gb/s CPFSK coherent multichannel transmission experiment forhigh capacity trunk line system

A 2.5-Gb/s CPFSK four-channel FDM transmission experiment has been conducted with a 150-km-long nondispersion-shifted fiber. This system employed a wideband channel space controller, a common polarization control, and a channel identification function. These were indispensable for realizing a high-capacity, coherent FDM trunk line system. The results of the experiment confirm the feasibility of trunk line systems with over 160-Gb/s capacity     

Time division multiplexed OTDR system

A new technique to increase the effective sampling rate of an optical time-domain reflectometer using a time division multiplexing digital sampling averaging procedure is proposed. This permits an increase in distance measuring accuracy of an optical time-domain reflectometer.     

Novel repeated batch operation for flash fermentation system: Experimental data and mathematical modelling

A novel repeated batch operation mode was proposed for ethanol fermentation, where the fermenter beer was periodically exchanged between the fermenter with biomass recycle and the distillation unit, to promote the selective removal of ethanol. Using the mathematical model developed, as based on the experimental results, the optimal operation of the proposed method was shown to attain high performance, with a productivity of about 12 g dm⁻³ h⁻¹ and a product concentration of 400 g dm⁻³.     

Characterization of neurons differentiated from mouse embryonic stem cells using conditioned medium of dorsal root ganglia

Mouse embryonic stem (ES) cells have the pluripotent ability to differentiate in vitro into various cell lineages, including neurons. Adding chick dorsal root ganglion (DRG) conditioned medium (CM) to the culture medium promotes the differentiation of ES cells into neurons. We determined the types of neurons that differentiate from ES cells. The addition of DRG-CM caused nearly half of all ES cells on the periphery of the colony sphere to differentiate into neurons. Immunofluorescence analysis showed that the neurons that differentiated from ES cells were mainly motor, GABAergic, serotonergic, and cholinergic neurons. Of particular note, flow cytometry showed that approximately 50% of betaIII-tubulin-positive neurons were motor neurons. This indicates that DRG-CM induces ES cells to differentiate into motor neurons as target of DRG neurons (sensory neurons).