Sol-gel ZnO-SiO/sub 2/ composite waveguide ultraviolet lasers

Random laser action with coherent feedback is realized in ZnO-SiO/sub 2/ composite films, which consists of ZnO clusters embedded in SiO/sub 2/ dielectric matrix prepared by sol-gel technique. The films are deposited on silicon substrate with a SiO/sub 2/ buffer layer to form a waveguide structure. Ultraviolet lasing at room temperature is observed from the composite films with ZnO : SiO/sub 2/ molar ratio varying between 1 : 5 and 1 : 30. The corresponding lasing wavelength and linewidth under 355-nm optical excitation are found to be /spl sim/388 nm and less than 0.6 nm, respectively. Our experiment has shown that the proper control of light confinement inside the random cavities leads to coherent random lasing.     

The near-zone field characteristics of an E-polarization plane wavepenetrating through cylindrical multiple apertures (non) coated withlossy and lossless media

The direct integral equation is formulated for describing the current on the multiple perfectly conducting strips in cylindrical geometries for an E-polarization plane wave of normal incidence. By using the Galerkin's method, the surface currents on the conducting strips are expanded in the form of a series of Chebyshev polynomials of the first kind, while the unknown expanding coefficients are solved by a set of matrix equations of finite order with a fast convergence rate and a high accuracy. Furthermore, numerical results are presented to demonstrate the variation of the penetrated near-zone field in the presence of one, two, three, four and six cylindrical apertures, and the hybrid effects of both aperture number and aperture angular widths on the penetrated fields are investigated in detail     

Application of simulated annealing to the biclustering of gene expression data.

In a gene expression data matrix, a bicluster is a submatrix of genes and conditions that exhibits a high correlation of expression activity across both rows and columns. The problem of locating the most significant bicluster has been shown to be NP-complete. Heuristic approaches such as Cheng and Church's greedy node deletion algorithm have been previously employed. It is to be expected that stochastic search techniques such as evolutionary algorithms or simulated annealing might improve upon such greedy techniques. In this paper we show that an approach based on simulated annealing is well suited to this problem, and we present a comparative evaluation of simulated annealing and node deletion on a variety of datasets. We show that simulated annealing discovers more significant biclusters in many cases. Furthermore, we also test the ability of our technique to locate biologically verifiable biclusters within an annotated set of genes.     

Power-amplifier modules covering 70-113 GHz using MMICs

A set of W-band power amplifier (PA) modules using monolithic microwave integrated circuits (MMICs) have been developed for the local oscillators of the far-infrared and sub-millimeter telescope (FIRST). The MMIC PA chips include three driver and three PAs, designed using microstrip lines, and another two smaller driver amplifiers using coplanar waveguides, covering the entire W-band. The highest frequency PA, which covers 100-113 GHz, has a peak power of greater than 250 mW (25 dBm) at 105 GHz, which is the best output power performance for a monolithic amplifier above 100 GHz to date. These monolithic PA chips are fabricated using 0.1-μm AlGaAs/InGaAs/GaAs pseudomorphic T-gate power high electron-mobility transistors on a 2-mil GaAs substrate. The module assembly and testing, together with the system applications, is also addressed in this paper     

Series Representations for Rice's Ie Function

Two new series representations for the Rice functionIe (k, x)are presented. One of the series involves the modified Struve functions and the other involves the modified Bessel functions. These two series complement each other in their convergence speeds as functions of the values ofkandx. The truncation error bounds are derived for both series. Therefore, they can be used alternatively with high efficiency and known precision.     

叠层MRAM封装的磁屏蔽

MRAM是一种很有希望的通用存储器候选技术。因为它具有非易失性、高速度、与常规CMOS的兼容性。以及抗辐射的潜力。PoP堆叠技术能够提高封装存储密度并有效地解决磁屏蔽问题。     

Investigation of the fluid/structure interaction phenomenon in IC packaging

In the present study, experiment and simulation studies were conducted on the fluid/structure interaction (FSI) analysis of integrated circuit (IC) packaging. The visualisation of FSI phenomenon in the actual package is difficult due to limitations of package size, available equipment, and the high cost of the experimental setup. However, the experimental data are necessary to validate the simulation results in the FSI analysis of IC packaging. Scaled-up package size was fabricated to emulate the encapsulation of IC packaging and to study the effects of FSI phenomenon in the moulded package. The interaction between the fluid and the structure was observed. The deformation of the imitated chip was studied experimentally. The air-trap mechanism that occurred during the experiment is also presented in this paper. Simulation technique was utilised to validate the experimental result and to describe the physics of FSI. The predicted flow front was validated well by the experiment. Hence, the virtual modelling technique was proven to be excellent in handling this problem. The study also extends FSI modelling in actual-size packaging.     

Biocatalytic Nanoscale Coatings Through Biomimetic Layer‐by‐Layer Mineralization

Recent insight into the molecular mechanisms of biological mineral formation (biomineralization) has enabled biomimetic approaches for the synthesis of functional organic‐inorganic hybrid materials under mild reaction conditions. Here we describe a novel method for enzyme immobilization in thin (nanoscale) conformal mineral coatings using biomimetic layer‐by‐layer (LbL) mineralization. The method utilizes a multifunctional molecule comprised of a naturally‐occurring peptide, protamine (PA), covalently bound to the redox enzyme Glucose oxidase (GOx). PA mimics the mineralizing properties of biomolecules involved in silica biomineralization in diatoms, and its covalent attachment to GOx does not interfere with the catalytic activity. Highly efficient and stable incorporation of this modified enzyme (GOx‐PA) into nanoscale layers (～5–7 nm thickness) of Ti‐O and Si‐O is accomplished during protamine‐enabled LbL mineralization on silica spheres. Depending on the layer location of the enzyme and the type of mineral (silica or titania) within which the enzyme is incorporated, the resulting multilayer biocatalytic hybrid materials exhibit between 20–100% of the activity of the free enzyme in solution. Analyses of kinetic properties (V_max, K_M) of the immobilized enzyme, coupled with characterization of physical properties of the mineral‐bearing layers (thickness, porosity, pore size distribution), indicates that the catalytic activities of the synthesized hybrid nanoscale coatings are largely determined by substrate diffusion rather than enzyme functionality. The GOx‐PA immobilized in these nanoscale layers is substantially stabilized against heat‐induced denaturation and largely protected from proteolytic attack. The method for enzyme immobilization described here enables, for the first time, the high yield immobilization and stabilization of enzymes within continuous, conformal, and nanoscale coatings through biomimetic LbL mineralization. This approach will likely be applicable to a wide variety of surfaces and functional biomolecules. The ability to synthesize thin (nanoscale) conformal enzyme‐loaded layers is of interest for numerous applications, including enzyme‐based biofuel cells and biosensors.     

Entropy-based measures for quantifying sleep-stage transition dynamics: relationship to sleep fragmentation and daytime sleepiness

We present two novel entropy-based measures that quantify sleep-stage transition dynamics (sleep structure) from polysomnogram derived hypnograms: Walsh spectral entropy (WSE) and Haar spectral entropy (HSE). These measures quantify patterns of temporal regularity of a categorical time series without requiring numerical encoding (scaling) of the (categorical) sleep stages. Additionally, we show that conditional entropy (CE) is well suited for quantifying predictability of the hypnogram. The relationship of those measures with traditional sleep fragmentation indices (arousal index, total sleep time, and sleep efficiency) is explored for a 394 participant sample of the Cleveland Family Study, an epidemiologic study in which standardized single-night polysomnogram data were collected. The new entropy-based sleep structure measures (WSE, HSE, and CE) are positively correlated (moderate to weak) with the traditional sleep fragmentation indices. Because the sleep structure measures developed in this paper provide direct information related to temporal patterns of sleep that is not contained in traditional sleep fragmentation measures, the correlation between these new alternative sleep structure measures and the traditional sleep fragmentation measures is less important. Our goal is not to develop alternative measures that correlate highly with traditional measures of sleep fragmentation, but rather to provide methods to quantify sleep structure by examining other (e.g., dynamic sleep-stage transition) properties of the hypnogram. Additionally, the relationship of the new entropy-based and traditional measures with daytime sleepiness as quantified by the Epworth sleepiness scale (ESS) is investigated. Multiple linear regression analysis shows that WSE has a stronger relationship with ESS than the traditional measures, even after both are adjusted for common confounders (age, race, gender, and body mass index). This further suggests that the entropy-based measures, especially WSE, are capturing additional temporal patterns of sleep not captured in the traditional sleep fragmentation measures, and have a relationship with daytime sleepiness.