The eye of Eila Hopper Ross

In 1936, when Eila Hopper Ross (nee Hopper) was putting the final stroke of paint on her six-foot oil canvas of a life model at the Ontario College of Art, she had not dreamed that in the year to follow she would embark upon a life's career of anatomical study and attention to intricate detail in her own work as a medical illustrator. Though she had early aspirations herself of going into medicine--having been raised in a medical environment with her father, Dr. David Alexander Hopper, regularly receiving pharmaceutical literature with impressive illustrations--Hopper Ross was not aware of medical illustration as a profession. It was Maria Wishart, then director of the Medical Art Service Unit at the University of Toronto, who saw Hopper Ross' final exhibition at the Ontario College of Art and recommended she consider a career in medical art. As a result, Hopper Ross studied for two years (1937-1939) in the Department of Art as Applied to Medicine at Johns Hopkins University in Baltimore, Maryland under the direction of Professor Max Br?del.     

A regulatory role for recombinase activating genes, RAG-1 and RAG-2, in T cell development

Effects of etoposide (VP-16) and cytosine arabinoside (Ara-C) on the cell cycle of HL-60 and THP-1 cells were studied by flow cytometry using the bromodeoxyuridine (BrdU)/DNA assay technique to investigate the efficacy of VP-16 for monocytic leukemia cells. VP-16 inhibited the proliferation of THP-1 cells more strongly than that of HL-60 cells at any concentrations used at 24 and 48 hr. VP-16 arrested HL-60 and THP-1 cells in the G2/M phase and reduced them in the G0/G1 and early S phase at higher concentrations. There was no significant difference in the percentage of G2/M phase cells at the same concentration between both cells. However, reduction in the G0/G1 and early S phase cells was more marked in THP-1 than HL-60 cells significantly. On the other hand, Ara-C perturbed the cell cycle of HL-60 cells more than that of THP-1 cells at 24 and 48 hr. These results suggest that the effects of VP-16 on the cell cycle may be more intense in THP-1 than HL-60 cells, and support the efficacy of VP-16 for treating monocytic leukemia in vivo.     

An Indexing Method for Answering Queries on Moving Objects

We consider the problem of indexing a set of objects moving in d-dimensional spaces along linear trajectories. A simple external-memory indexing scheme is proposed to efficiently answer general range queries. The following are examples of the queries that can be answered by the proposed method: report all moving objects that will (i) pass between two given points within a specified time interval; (ii) become within a given distance from some or all of a given set of other moving objects. Our scheme is based on mapping the objects to a dual space, where queries about moving objects are transformed into polyhedral queries concerning their speeds and initial locations. We then present a simple method for answering such polyhedral queries, based on partitioning the space into disjoint regions and using a B+-tree to index the points in each region. By appropriately selecting the boundaries of each region, we guarantee an average search time that matches a known lower bound for the problem. Specifically, for a fixed d, if the coordinates of a given set of N points are statistically independent, the proposed technique answers polyhedral queries, on the average, in O((N/B)^1−1/d⋅(log _B N)^1/d+K/B) I/O's using O(N/B) space, where B is the block size, and K is the number of reported points. Our approach is novel in that, while it provides a theoretical upper bound on the average query time, it avoids the use of complicated data structures, making it an effective candidate for practical applications. The proposed index is also dynamic in the sense that it allows object insertion and deletion in an amortized update cost of log _B(N) I/O's. Experimental results are presented to show the superiority of the proposed index over other methods based on R-trees. recommend Ahmed Elmagarmid     

An optimal deployable bandwidth aggregation system

The explosive increase in data demand coupled with the rapid deployment of various wireless access technologies have led to the increase of number of multi-homed or multi-interface enabled devices. Fully exploiting these interfaces has motivated researchers to propose numerous solutions that aggregate their available bandwidths to increase overall throughput and satisfy the end-user’s growing data demand. These solutions, however, do not utilize their interfaces to the maximum without network support, and more importantly, have faced a steep deployment barrier. In this paper, we propose an optimal deployable bandwidth aggregation system (DBAS) for multi-interface enabled devices. We present the DBAS architecture that does not introduce any intermediate hardware, modify current operating systems, modify socket implementations, nor require changes to current applications or legacy servers. The DBAS architecture is designed to automatically estimate the characteristics of applications and dynamically schedule various connections and/or packets to different interfaces. We also formulate our optimal scheduler as a mixed integer programming problem yielding an efficient solution. We evaluate DBAS via implementation on the Windows OS and further verify our results with simulations on NS2. Our evaluation shows that, with current Internet characteristics, DBAS reaches the throughput upper bound with no modifications to legacy servers. It also highlights the significant enhancements in the response time introduced by DBAS, which directly enhances the user experience.     

Estimated daily intake of pesticide residues exposure by vegetables grown in greenhouses in Al-Qassim region,Saudi Arabia

Residues of 23 pesticides (13 insecticides, 3 fungicides, 3 herbicides, 2 acaricides, 1 rodenticide and 1 nematicide) in 160 different vegetable samples cultivated under greenhouse conditions and collected from 4 major supermarkets located in Al-Qassim region, Saudi Arabia were monitored. A multiresidue method was carried out by gas chromatography with mass spectrometry (GC–MS). Residues were found in 89 samples. Fifty four samples were found above the maximum residue levels (MRLs). The most frequently found pesticides were carbaryl followed by biphenyl and then carbofuran. MRL values exceeded most often in cabbage (11 samples) followed by squash, green pepper and carrot (7 samples each) followed by cucumber and lettuce (6 samples each), egg-plant (5 samples) and then tomato (4 samples). Also, cabbage showed the highest contamination rates (16 samples), followed by carrot, cucumber and green pepper (12 samples each), squash (11 samples), lettuce and tomato (9 samples each) and egg-plant (8 samples). The highest concentrations were determined in lettuce followed by squash, cabbage and carrot. Al-Qassim region population’s average daily intake (EDI) has been estimated between 2 × 10^?5 and 0.597 μg/kg body weight/day and the hazard index (EDI/acceptable daily intake (ADI)) less than the unity for the tested compounds. The data illustrated that the intakes are much lower than the ADIs and the exposure level to whole pesticides was below the level to produce health risk. The data indicated also the need for regular monitoring programs for pesticide residues in vegetables cultivated under greenhouse conditions, at the national level, to protect consumers’ health.     

Privacy Analysis of Forward and Backward Untraceable RFID Authentication Schemes

In this paper, we analyze the first known provably secure Radio Frequency Identification (RFID) authentication schemes that are designed to provide forward untraceability and backward untraceability: the L-K and S-M schemes. We show how to trace tags in the L-K scheme without needing to corrupt tags. We also show that if a standard cryptographic pseudorandom bit generator (PRBG) is used in the S-M scheme, then the scheme may fail to provide forward untraceability and backward untraceability. To achieve the desired untraceability features, we show that the S-M scheme can use a robust PRBG which provides forward security and backward security. We also note that the backward security is stronger than necessary for the backward untraceability of the S-M scheme.     

2D and 3D numerical simulation of the wind-rotor/nacelle interaction in an atmospheric boundary layer

Two-dimensional axisymmetric and three-dimensional steady turbulent flow computations around two horizontal-axis wind turbines (Nordex N80 and Jeumont J48) are carried out to investigate the wind-rotor/nacelle interaction and quantify its effects on the wind speed at the nacelle anemometry. The actuator disk concept has been used to model the action of the blades. For both turbines, the geometry of the nacelle was reproduced as faithfully as possible. The terrain was represented by an appropriate law of the wall to account for roughness with particular attention paid to the boundary conditions in order to reproduce the neutral atmospheric boundary layer. The calculated velocity field in the vicinity of the nacelle exhibits good agreement with available experimental data. The results also show that for a complex nacelle geometry, like that of the N80, a three-dimensional calculation is necessary to obtain a good prediction of the velocity field in the near wake. The hub height effect is evaluated for the J48 by raising the nacelle from a height of 36 to 60 m. No significant impact is noted on the ratio nacelle wind speed/freestream wind speed.     

Partially bonded near-surface-mounted CFRP bars for strengthened concrete T-beams

A partially bonded strengthening approach for reinforced concrete (RC) beams utilizing near-surface-mounted (NSM) carbon fiber reinforced polymer (CFRP) bars was investigated with the specific objective of improving deformability. A total of six RC T-beams strengthened with NSM CFRP bars of various unbonded lengths were tested. Test results showed a decrease of the stiffness at the post-yield stage of the load–deflection response in the partially bonded beams. This is caused by the delayed increase of the FRP strain within the unbonded length. As a result the beam deformability was increased as the unbonded length increased at the same applied load. Internal slip of the FRP bar and gradual concrete failure were observed near the ultimate state, which caused a complicate nonlinear behavior of the beams. An analytical model is proposed to address the complete beam behavior including the effect of slip of FRP reinforcement and gradual concrete crushing. This model was developed based on the compatibility of deformation of the partially bonded system and was able to represent the ultimate behavior of the beams well.