Study of cycle output improvement by work-fluid including phase change material

This paper deals with the output improvement of heating and cooling cycle by using the work-fluid including phase change material.The experimental study is carried out by heat exchange between work-fluid and heat transfer surface.The work-fluid is flown to a high temperature or a low temperature heat transfer surface from the narrow path.In order to increase the amount of the heat transmission,a trace of Diethylether(boiling point 34.8 ℃),as a phase change material(PCM),is added to the work-fluid.The parameters of the experiment are additive amount of PCM,the rotational speed of the displacer piston and the temperature of heat transfer surface.It is clarified that the increasing of engine cycle output is brought by the PCM addition.The effect of PCM addition is evaluated by output ratio which is defined from the experimental cycle output data.The requirements for acquiring the increasing effect of output by adding PCM are clarified.     

Quantum Dynamics of Atom-Molecule BECs in a Double-Well Potential

We investigate the dynamics of two-component Bose-Josephson junction composed of atom-molecule BECs. Within the semiclassical approximation, the multi-degree of freedom of this system permits chaotic dynamics, which does not occur in single-component Bose-Josephson junctions. By investigating the level statistics of the energy spectra using the exact diagonalization method, we evaluate whether the dynamics of the system is periodic or non-periodic within the semiclassical approximation. Additionally, we compare the semiclassical and full-quantum dynamics.     

Small Molecule Alkoxy Oriented Selectiveness on Human Carbonic Anhydrase II and IX Inhibition

We report aryl sulfonamide inhibitors of human carbonic anhydrase (hCA; EC 4.2.1.1) enzymes containing short ureido alkoxy tails. The inhibition potency of such compounds was investigated in vitro on the major hCA isoforms (i.e. I, II, IX, and XII). A selection of the most potent inhibitory derivatives against the hCA IX isoform (i.e. 5a, 5c, and 6c) was studied, and their binding modes on either hCA II and IX-mimic isoform were assessed by X-ray crystallography on the corresponding ligand/protein adducts. This study adds to the field of developing hCA inhibitors at molecular level the critical interactions governing ligand selectivity.     

Nanoarchitectonics of PEG-Coated Ni-Zn Ferrite Nanoparticles and Mechanical Analysis of Heat Generation by Magnetic Relaxation

The magnetic relaxation of magnetic nanoparticles (MNPs) has been used as a potential heating agent for magnetic hyperthermia treatment (MHT). This requires an understanding of the heating mechanism of MNPs, such as Néel relaxation; however, few studies about magnetic relaxation using a low-frequency AC magnetic field have been reported. This study attempts to clarify the correlation between the dominance of Néel relaxation in low-frequency AC fields and the magnetic properties. Nanoparticles of Ni_0.8Zn_0.2Fe₂O₄ coated with poly(ethylene glycol) (PEG) were synthesized in various sizes (d?=?12, 15, and 19 nm), and were subjected to structural analysis, PEG modification, and magnetic measurements. The PEG400 coating results in a hydrodynamic diameter ten times smaller than that of our previous sample. The heat generation experiment was conducted on samples suspended in solvents of different viscosities in the presence of an AC field (h?=?3.2 kAm^?1, f?=?90 kHz). The specific absorption rate (SAR) as a function of the viscosity of the 15-nm NP sample is consistent with the theoretically calculated value in cases where the Néel relaxation is dominant. Therefore, we conclude that the Néel relaxation dominates the heating mechanism of the 15 nm sample. Rather than being fully superparamagnetic, this sample was partly superparamagnetic and slightly ferromagnetic, with the dominance of the Néel relaxation to a certain degree affected by spin blocking. Detailed analysis of the magnetic relaxation is crucial to improve the heating efficiency of MNPs for MHT.

     

Experiment of cryo-compressed (90-MPa) hydrogen leakage diffusion

To improve safety regulations for fuel cell vehicles and hydrogen infrastructures, experiments on cryo-compressed hydrogen leakage diffusion were conducted. The experimental apparatus can supply 90 MPa hydrogen at various temperature conditions (50 K–300 K) at a maximum flow rate of 100 kg/h. The hydrogen leakage flow rate was measured using pinhole nozzles with different outlet diameters (0.2 mm, 0.4 mm, 0.7 mm, and 1 mm). It was confirmed that the hydrogen leakage flow rate increases as the supply temperature decreases. To evaluate the hydrogen flow rate including the cryogenic condition, the orifice equation for liquid was found to be appropriate. The orifice flow coefficient converged to a constant value of 0.6 on the high-density condition side. The hydrogen concentration distribution was measured by injecting high-pressure hydrogen from the 0.2-mm pinhole for 10 min under a constant pressure/temperature condition. The axial hydrogen concentration distribution obtained by the ambient temperature (～300 K) hydrogen injection test well agreed with the experimental formula based on previous research studies. In addition, as the hydrogen injection temperature decreased, it was found that the hydrogen concentration increased, and an empirical formula of the 1% concentration distance for the cryogenic hydrogen system was newly presented. Additional tests were conducted using pinholes of different diameters, and a 1% concentration distance was confirmed to be proportional to the hydrogen leakage flow rate to the 0.5th power.     

Fluorescent aplyronine a: intracellular accumulation and disassembly of actin cytoskeleton in tumor cells

Nonstick: Aplyronine A (ApA) is an antitumor and apoptogenic macrolide of marine origin. We prepared a fluorescent derivative of ApA that accumulated strongly throughout the cytoplasm and caused the rapid disassembly of the actin cytoskeleton in tumor cells. We also established that ApA caused malfunction of cell adhesion and dephosphorylation of focal adhesion kinase with apoptosis.     

Clinical significance of matrix metalloproteinase-9 and tissue inhibitor of matrix metalloproteinase-1 in peripheral blood of patients with gastric carcinoma

Matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of matrix metalloproteinase-1 (TIMP-1) in peripheral blood were measured in 54 patients with gastric carcinoma; 46 were primary and 8 were recurrent cases. There were no significant associations between MMP-9 concentrations and clinicopathological factors. TIMP-1 levels were significantly increased in advanced and recurrent cases, and in cases with peritoneal dissemination and lymph node metastasis, suggesting that TIMP-1 concentration in the peripheral blood could be a new tumor marker for the recurrence of gastric carcinoma.     

On the Rapid Synthesis of the Ternary Mo2GaC

The reaction path to form the Mo₂GaC MAX phase starting with Mo, Ga, and C (molar ratio, 2:1.2:1) powders was investigated in the 850°C and 1000°C temperature range. It was found that Mo₂GaC could be synthesized from reactions between Mo₃Ga and C or Mo₂C and Ga. Powders that contained >90 wt% Mo₂GaC were successfully fabricated by heating a 1:1.4 molar ratio of Mo₂C:Ga to 900°C for 24 h under flowing argon, followed by the dissolution of excess Ga by HCl. The a‐ and c‐lattice parameters were measured to be 3.022(1) and 13.179(5) Å.