A New Hand-Held Microsystem Architecture for Biological Analysis

This paper presents a hand-held microsystem based on new fully integrated magnetoresistive biochips for biomolecular recognition (DNA hybridization, antibody antigen interaction, etc.). Magnetoresistive chip surfaces are chemically treated, enabling the immobilization of probe biomolecules such as DNA or antibodies. Fluid handling is also integrated in the biochip. The proposed microsystem not only integrates the biochip, which is an array of 16times16 magnetoresistive sensors, but it also provides all the electronic circuitry for addressing and reading out each transducer. The proposed architecture and circuits were specifically designed for achieving a compact, programmable and portable microsystem. The microsystem also integrates a hand-held analyzer connected through a wireless channel. A prototype of the system was already developed and detection of magnetic nanoparticles was obtained. This indicates that the system may be used for magnetic label based bioassays     

An optically clocked transistor array with dual serial-to-parallel and parallel-to-serial conversion capability for optical label swapping

We propose an optically clocked transistor array optoelectronic integrated circuit (OEIC) for both serial-to-parallel and parallel-to-serial conversion (demux/mux), enabling an interface between high-speed asynchronous burst optical labels and CMOS circuitry for optical label swapping. Dual functionality of the OEIC reduces size, power, and cost of the optical label swapper. The capability for greater than 20-Gb/s conversion operation is demonstrated.     

Multi-level attention model for tracking and segmentation of objects under complex occlusion

A multi-level attention framework for tracking and segmentation of humans and objects under complex occlusions is investigated, featuring an effective probabilistic appearance-based technique for pixel reclassification during object grouping and splitting. A novel ’spatial-depth affinity metric’ is introduced in the conventional likelihood function, utilising information of both spatial locations of pixels and dynamic depth ordering of the component objects in grouping. Depth ordering estimation is achieved through a combination of top-down and bottom-up approach. Experiments on some realworld difficult scenarios of low quality and highly compressed videos demonstrate the very promising results achieved.     

Knowledge-based control and case-based diagnosis based upon empirical knowledge and fuzzy logic for the SBR plant.

Because biological wastewater treatment plants (WWTPs) involve a long time-delay and various disturbances, in general, skilled operators manually control the plant based on empirical knowledge. And operators usually diagnose the plant using similar cases experienced in the past. For the effective management of the plant, system automation has to be accomplished based upon operating recipes. This paper introduces automatic control and diagnosis based upon the operator's knowledge. Fuzzy logic was employed to design this knowledge-based controller because fuzzy logic can convert the linguistic information to rules. The controller can manage the influent and external carbon in considering the loading rate. The input of the controller is not the loading rate but the dissolved oxygen (DO) lag-time, which has a strong relation to the loading rate. This approach can replace an expensive sensor, which measures the loading rate and ammonia concentration in the reactor, with a cheaper DO sensor. The proposed controller can assure optimal operation and prevent the over-feeding problem. Case-based diagnosis was achieved by the analysis of profile patterns collected from the past. A new test profile was diagnosed by comparing it with template patterns containing normal and abnormal cases. The proposed control and diagnostic system will guarantee the effective and stable operation of WWTPs.     

Photocatalytic oxidation of low concentration 2,4-D solution with new TiO2 fiber catalyst in a continuous flow reactor.

Environmental pollution by low concentrations of 2,4-Dichlorophenoxyacetic acid (2,4-D) is a concern these days due to ever increasingly stringent regulations. Photocatalysis with immobilized TiO2 fiber is a promising oxidation method. Laboratory experiments on photocatalytic degradation of 0.045 mmol l(-1) 2,4-D with the world's first high-strength TiO2 fiber catalyst were carried out in a continuous flow reactor in which the degradations were, in general, similar to those with high 2,4-D concentrations investigated elsewhere. Degradation and mineralization of 2,4-D were significantly enhanced with no initial pH adjustments. The rate constants for total organic carbon (TOC) without pH adjustment were about two-fold bigger than the pH adjustment cases. CO2 gas measurement and carbon mass-balance were carried out for the first time, where about 34% organic carbon converted into CO2 gas during four-hour oxidation. 2,4-Dichlorophenol (2,4-DCP), phenol, benzyl alcohol and two unknowns (RT = 2.65 and 3.78 min.) were detected as aromatic intermediates while Phenol was the new aromatic in HPLC analysis. Dechlorination efficiencies were high (> 70%) in all the cases, and more than 90% efficiencies were observed in chloride mass balance. Bigger flow rates and solution temperature fixed at 20 degrees C without pH adjustment greatly enhanced 2,4-D mineralization. These results can be an important basis in applying the treatment method for dioxin-contaminated water and wastewater.     

Dominant rock properties affecting the performance of conical picks and the comparison of some experimental and theoretical results

Conical picks are the essential cutting tools used especially on roadheaders, continuous miners and shearers and their cutting performance affects directly the efficiency and the cost of rock/mineral excavation. In this study, in order to better understand the effects of dominant rock properties on cutter performance, 22 different rock specimens having compressive strength values varying from 10 to 170 MPa are first subjected to a wide range of mechanical tests. Then, laboratory full-scale linear cutting tests with different depth of cut and cutter spacing values are realized on large blocks of rock specimens using one type of conical pick. Specific energy, cutting and normal force values for relieved and unrelieved cutting modes are recorded using a triaxial force dynamometer with capacity of 50 tonnes and a data acquisition system. Cutter force and specific energy values are correlated with rock properties and theoretical force and specific energy values obtained from widely used theoretical approaches.The results indicate that uniaxial compressive strength among the rock properties investigated is best correlated with the measured cutter performance values, which is in good agreement with previous studies. However, it is also emphasized in this study that Brazilian tensile strength, Schmidt hammer rebound values, static and dynamic elasticity modulus are also dominant rock properties affecting cutter performance.Theoretical specific energy defined by different researchers has a meaningful relationship with the experimental specific energy, which is an essential parameter for predicting the instantaneous cutting rates of mechanical excavation systems. It is also demonstrated that the experimental cutter forces obtained for 5 mm depth of cut are in good agreement with theoretical force values, if the friction angle between rock and cutting tool is included in the theoretical formulation. It is emphasized that, to some extend, laboratory tests can help to minimize high cost of a trial–error approach in the field.     

A tree partitioning dynamic policy for OVSF codes assignment in wideband CDMA

This paper proposes some novel techniques to accommodate users with different rate requirements in a wideband code-division multiple-access system employing orthogonal variable spreading factor codes. Two simple static code assignment strategies are first considered, and an improvement based on multicode assignment. Then the new idea of tree partitioning is introduced and used to devise a dynamic code reassignment algorithm. The behavior of these different techniques is experimentally investigated, in terms of call blocking probability and number of required reassignments. The tree partitioning method exhibits very good performances.     

Catalytic aminolysis of epoxide by alumina prepared from amine-protected Al precursor

The catalytic activities of alumina prepared from an Al alkoxide-amine adduct monomer for the reaction of cyclopentene oxide with piperidine was determined after various pretreatments, including calcination and exposure to moisture. They were compared with the activity of alumina prepared by the conventional hydrolysis method. It was found that the as-prepared sample from the alkoxide-amine monomer preparation was five times more active than a conventional preparation, suggesting that it has a higher density of surface Lewis acid sites. However, its activity was much more severely suppressed by exposure to moisture.     

Citation patterns in the Kuwaiti journal Medical Principles and Practice: The first 12 years, 1989-2000

This study investigates the citation patterns in the journal, Medical Principles and Practice from its inception in 1989 through 2000 (volumes 1-9). The data set includes 4740 references appended to the 221 original research articles. All of the citations were entered into a ProCite database for analysis. Specifically, this study addresses: (1) bibliometric patterns of cited works in terms of publication format, subject scatter, authorship characteristics, age of citations, geographic distribution, and language distribution; (2) productivity of journal titles; (3) the role of self-citation; and (4) how selected bibliometric indicators apply. Some of the findings include: journal articles are most frequently cited; English language publications dominate the literature; there is a trend of multiple authorship; and the pattern of aging is below the norm for medical literature. The results of the study can provide a benchmark to measure the user behavior of a particular group of researchers as well as for the provision of collection development and management decisions. This revised version was published online in August 2006 with corrections to the Cover Date.