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91.
92.
Abstract

Emerging intrastate transboundary issues focus on use of the Mahomet aquifer, which underlies about fifteen counties and many other political entities in east-central Illinois. This sand and gravel aquifer in the lower part of the buried Mahomet Bedrock Valley ranges between four and fourteen miles wide and from about 50 to 200 feet thick. Much of the region's rural population, several large communities, and many small towns obtain water from the Mahomet aquifer, as do industrial, agricultural, and commercial users. Increased development of the Mahomet aquifer to meet growing demands for water has caused conflicts over real or perceived adverse effects. One result has been the creation of fifteen resource protection zones and twelve water authorities. For groundwater supplies, resource protection zones help municipalities protect water-supply wells from potential adverse impacts. Many resource protection zones overlap one another, however, so this situation could lead to disputes over use of the resource. The reason that several of the twelve water authorities were organized was to meet a challenge perceived from a demand to be placed on the aquifer, in other words, a potential for conflict of use. Complicating the situation is that some of the water authorities overlap the resource protection zones. This could lead to disputes not only about water use, but also over which jurisdiction has the authority to settle a dispute. The Mahomet Aquifer Consortium was recently organized by concerned people representing diverse groundwater interests at the local level, including the private sector, professional organizations, and various governmental units. The consortium brings together representatives of some groups that typically did not communicate with each other in the past. The consortium may provide a forum through which emerging transboundary issues pertaining to use of the Mahomet aquifer can be addressed. Because the consortium is a voluntary organization that relies on consensus building, the success it may achieve in resolving future conflicts over groundwater use from the Mahomet aquifer remains to be seen.  相似文献   
93.
Social networks play an important role in environmental governance regimes, and they are a key to the adaptive capacity of systems that deal with complex, contextual and multi-faceted issues. Urban water systems are typical examples of complex systems facing many pressures, such as increased population, water quality deterioration, and climate change. This paper explores social networks of the key stakeholders engaged in urban water management, in Makassar City, Indonesia, in the context of exploring ways to improve management of an increasingly complex urban water system. Three social networks were explored; those constituted by formal and informal interactions and networks perceived by stakeholders to be “ideal”. Formal networks were identified through an examination of the legislative instruments and government agencies’ documents relating to water provision in Makassar, while the informal and “ideal” networks were investigated in collaboration with the stakeholders. The research found that the informal social network was more extensive than were the formally required networks, and the investigation of informal networks created a potentially more robust and adaptive water management system than would have occurred through inclusion of formal institutional arrangements. We suggest that in examination of the adaptive capacity of an urban water system, one also considers the informal arrangements and linkages, as this additional information about the system is necessary to enhance our understanding of potential adaptation of water management and improved urban water systems.  相似文献   
94.
The “median” method for the reduction of the effect of noise and trigger jitter on waveform data is described. The effectiveness of this method was examined using simulations and experiments and, for typical jitter and noise observed in electrical pulse metrology, is shown to provide reconstructed waveforms with transition durations that accurately match those of the input signal. Also, for aberrations, an upper bound on the error in the amplitude of the aberration is provided.  相似文献   
95.
External sorting: run formation revisited   总被引:1,自引:0,他引:1  
External mergesort begins with a run formation phase creating the initial sorted runs. Run formation can be done by a load-sort-store algorithm or by replacement selection. A load-sort-store algorithm repeatedly fills available memory with input records, sorts them, and writes the result to a run file. Replacement selection produces longer runs than load-sort-store algorithms and completely overlaps sorting and I/O, but it has poor locality of reference resulting in frequent cache misses and the classical algorithm works only for fixed-length records. This paper introduces batched replacement selection: a cache-conscious version of replacement selection that works also for variable-length records. The new algorithm resembles AlphaSort in the sense that it creates small in-memory runs and merges them to form the output runs. Its performance is experimentally compared with three other run formation algorithms: classical replacement selection, Quicksort, and AlphaSort. The experiments show that batched replacement selection is considerably faster than classic replacement selection. For small records (average 100 bytes), CPU time was reduced by about 50 percent and elapsed time by 47-63 percent. It was also consistently faster than Quicksort, but it did not always outperform AlphaSort. Replacement selection produces fewer runs than Quicksort and AlphaSort. The experiments confirmed that this reduces the merge time whereas the effect on the overall sort time depends on the number of disks available.  相似文献   
96.
The three-dimensional (3-D) X-ray crystal microscope is a new nondestructive tool for the 3-D characterization of the mesoscopic and nanoscopic materials structure. A prototype microscope is installed on beamline 34-ID at the advanced photon source and has begun initial operation. The prototype microscope has a routine spatial resolution of approximately 0.5 × 0.5 × 1 μm3 and can probe tens to hundreds of microns below a sample surface, depending on the composition of the sample. For each volume element measured, the microscope can determine between 10 and 16 parameters. The measured parameters are the local crystallographic phase (1 deg of freedom), the Eulerian angles of crystal orientation (3 deg of freedom), and the plastic and/or elastic strain-tensor elements (6 to 12 deg of freedom). The time required to collect each volume element varies between 1 and 14 seconds, depending on the precision of the parameters and the sample complexity. Much faster data acquisition and much better spatial resolution are certain in the near future. Some initial results are presented to illustrate how the 3-D X-ray crystal microscope can provide unprecedented information about the 3-D structure of materials. This article is based on a presentation made at the symposium “Characterization and Representation of Material Microstructures in 3-D” held October 8–10, 2002, in Columbus, OH, under the auspices of ASM International’s Phase Transformations committee.  相似文献   
97.
Standard atom probe tomography spatial reconstruction techniques have been reasonably successful in reproducing single crystal datasets. However, artefacts persist in the reconstructions that can be attributed to the incorrect assumption of a spherical evaporation surface. Using simulated and experimental field evaporation, we examine the expected shape of the evaporating surface and propose the use of a variable point projection position to mitigate to some degree these reconstruction artefacts. We show initial results from an implementation of a variable projection position, illustrating the effect on simulated and experimental data, while still maintaining a spherical projection surface. Specimen shapes during evaporation of model structures with interfaces between regions of low- and high-evaporation-field material are presented. Use of two-and three-dimensional projection-point maps in the reconstruction of more complicated datasets is discussed.  相似文献   
98.
99.
Objectives: A new improved mometasone furoate (Elocon?) cream with an emulsification system that produces a stable emulsion has been developed. In order to register the product in various markets, it was essential to ensure the cream was topically well tolerated and that it was bioequivalent to the reference product.

Methods: Phase I clinical studies were performed to assess the local safety and tolerability upon multiple dosing of this new cream as well as to assess the single-dose bioequivalence relative to the marketed product. Bioequivalence was assessed using a vasoconstrictive assay (VCA) after a dose-duration pilot study was completed with the marketed Elocon cream.

Key findings: The new mometasone cream and its vehicle were nonirritating in healthy subjects during 21-day patch application (MCII <0.025). The positive control was moderately irritating in the same study. The pivotal VCA study enrolled 162 subjects with 105 detectors included in the analysis of bioequivalence. In the 105 detectors, the ratio (×100%) of AUEC values at ED50 for test vs. standard (90% CI) was 112.91% (105.55, 120.87), within the bioequivalence criteria of (80, 125).

Conclusions: These studies supported the registration of reformulated mometasone cream in various markets.  相似文献   
100.
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