伊拉克某油田注水站设计方案优化

伊拉克鲁迈拉油田CP00注水站设计规模为1 000 m3/h,注水压力为20 MPa。该注水站的设计方案及优化考虑了安全、环保、节能、节省投资等因素。重点介绍了CP00内向注水泵喂水的方案选择及设计优化,以及整体工艺流程的设计。     

Size Control and Characterization of Sn-Ag-Cu Lead-Free Nanosolders by a Chemical Reduction Process

Sn-3.0Ag-0.5Cu nanosolders were synthesized via a chemical reduction method. Polyvinyl pyrrolidone (PVP) and sodium borohydride (NaBH₄) were employed as surfactant and reducing agent, respectively. Ultraviolet–visible (UV–visible) absorption and x-ray diffraction patterns revealed that alloying had successfully taken place during the reduction process. Different amounts of PVP and NaBH₄ additions influenced the nanosolder particle size. Under varying reaction temperatures and pH values, various ranges of nanosolder size were obtained. Optimized nanosolders were studied by differential scanning calorimetry to investigate the depression of the melting temperature, and were analyzed by transmission electron microscopy to measure actual particle sizes. The dependence of the particle size on the melting temperature was observed. The melting point was depressed to 204.4°C when the average diameter of the nanosolders was 20 nm. Although SnO₂ was formed on the nanosolders, it could be cleaned by citric acid. These low-melting-temperature Sn-Ag-Cu nanosolders are candidates for use in lead-free interconnect applications.     

Amphiphilic drug interactions with model cellular membranes are influenced by lipid chain-melting temperature

Small-molecule amphiphilic species such as many drug molecules frequently exhibit low-to-negligible aqueous solubility, and generally have no identified transport proteins assisting their distribution, yet are able to rapidly penetrate significant distances into patient tissue and even cross the blood–brain barrier. Previous work has identified a mechanism of translocation driven by acid-catalysed lipid hydrolysis of biological membranes, a process which is catalysed by the presence of cationic amphiphilic drug molecules. In this study, the interactions of raclopride, a model amphiphilic drug, were investigated with mixtures of biologically relevant lipids across a range of compositions, revealing the influence of the chain-melting temperature of the lipids upon the rate of acyl hydrolysis.     

Dynamic stiffness removal for direct numerical simulations

A systematic approach was developed to derive non-stiff reduced mechanisms for direct numerical simulations (DNS) with explicit integration solvers. The stiffness reduction was achieved through on-the-fly elimination of short time-scales induced by two features of fast chemical reactivity, namely quasi-steady-state (QSS) species and partial-equilibrium (PE) reactions. The sparse algebraic equations resulting from QSS and PE approximations were utilized such that the efficiency of the dynamic stiffness reduction is high compared with general methods of time-scale reduction based on Jacobian decomposition. Using the dimension reduction strategies developed in our previous work, a reduced mechanism with 52 species was first derived from a detailed mechanism with 561 species. The reduced mechanism was validated for ignition and extinction applications over the parameter range of equivalence ratio between 0.5 and 1.5, pressure between 10 and 50 atm, and initial temperature between 700 and 1600 K for ignition, and worst-case errors of approximately 30% were observed. The reduced mechanism with dynamic stiffness removal was then applied in homogeneous and 1-D ignition applications, as well as a 2-D direct numerical simulation of ignition with temperature inhomogeneities at constant volume with integration time-steps of 5-10 ns. The integration was numerically stable and good accuracy was achieved.     

Global instability of elliptical hollow section beam-columns under compression and biaxial bending

The global instability of elliptical hollow section members under combined compression plus biaxial bending is studied in this paper by means of laboratory testing and numerical simulations. A total of 9 beam-column tests were carried out under different combinations of compression and bending about both principal axes. The material properties of the tested sections were determined by means of tensile coupon tests. All tested elliptical hollow sections were EHS 150×75×5, and three nominal member lengths of 1 m, 2 m and 3 m were considered. Graphs of applied load versus mid-span bending moment, based on theoretical first and second order elastic considerations and the experimental second order inelastic response, are presented and described. Numerical models were initially validated against the experimental data using measured material and geometric properties, including imperfections. The models were subsequently employed in parametric studies to assess the influence of member slenderness and cross-sectional aspect ratio on the structural response. Finally, based on the experimental and numerical findings, design rules for hot-finished EHS beam-columns were assessed and statistically verified.     

Development and performance advantages of industrial,automotive and aviation synthetic lubricants

The study and use of some types of syntbetic lubricants can be traced back 50 years.¹ Within the past twenty years, rapid advances in technology have resulted in syntbetic lubricants that can operate satisfactorily over temperature extremes well beyond the capabilities of conventional petroleum-based oils. Current emphasis is on the ability of some types of synthetic lubricants to allow more efficient system operation, with concomitant energy savings and extended equipment and oil life. Several definitions have been proposed for synthetic lubricants. In this paper, the authors define a synthetic lubricant as a product which consists of base fluids manufactured by chemical synthesis and containing necessary performance additives. Thus the base fluids are tailored, through specific chemical reactions, to meet predetermined physical and chemical quality targets. In this paper, discussion will be limited to (a) a review of the types of chemicals which have been studied for use in synthetic lubricants and (b) selected application data which dramatise some of the advantages gained through use of the synthetic lubricant.     

CD26 Induces Colorectal Cancer Angiogenesis and Metastasis through CAV1/MMP1 Signaling

CD26 has been reported as a marker for colorectal cancer stem cells endowed with tumor-initiating properties and capable of colorectal cancer (CRC) metastasis. In this study, we investigated the functional effect of CD26 on CRC angiogenesis and metastasis, and the potential underlying mechanism. The functional effects of CD26 overexpression or repression were determined by a wound healing experiment, and cell migration and invasion assays in vitro and in mouse models. Differentially expressed genes regulated by CD26 were identified by genome-wide mRNA expression array and validated by quantitative PCR. CD26 functionally regulated CRC cell migration and invasion in vitro and angiogenesis and metastasis in vivo. Genome-wide mRNA expression array and qPCR showed that MMP1 was up-regulated in CD26+ subpopulation, and a subsequent experiment demonstrated the regulatory effect of CD26 on MMP1 in CRC cell lines with CD26 repression or overexpression. Furthermore, overexpression of CAV1 abrogated the CD26-regulated MMP1 induction in CRC cell lines. This study demonstrated the functional roles of CD26 in inducing CRC migration, invasion, angiogenesis and metastasis and identified the potential involvement of MMP1 and CAV1 in such process. CD26 is an attractive therapeutic target for combating tumor progression to improve the prognosis of CRC patients.     

Drying Kinetics,Texture, Color,and Determination of Effective Diffusivities During Sun Drying of Chempedak

Sun drying of chempedak (Artocarpus integer) was carried out on different sample sizes to investigate the effects on product quality. Fick's second law model was used to determine the effective diffusivities of sun–dried chempedak slabs based on the drying rate versus moisture content plots. In addition, texture degradation and total color changes were investigated. The texture and color changes of dried chempedak were relatively significant (p < 0.05) compared to fresh chempedak. There was an increase in dried fruit hardness and chewiness but a decrease in springiness and cohesiveness during drying.     

Effects of buffer gas composition on low temperature ignition of iso-octane and n-heptane

Experimental and numerical studies have been performed on the thermal and chemical effects of buffer gas composition on low temperature ignition of iso-octane and n-heptane. Experiments were conducted using a recently developed rapid compression machine in the temperature range of 600–850 K. Three buffer gases were studied including nitrogen (N₂), argon (Ar), and a mixture of Ar and carbon dioxide (CO₂) at a mole ratio of 65.1%/34.9%. Iso-octane was studied at 20 bar, ? = 1, and a dilution level of buffer gas to O₂ of 3.76:1 (mole ratio). n-Heptane was studied at 9 bar, ? = 1, and a dilution level of buffer gas to O₂ of 5.63:1 (mole ratio). For experiments where two-stage ignition was observed, the buffer gas composition had no impact on the first-stage ignition time but, as expected, it caused differences in the total heat release, pressure and temperature rise after the first-stage ignition. As a consequence, significant differences were observed for the total ignition delay time as a function of the buffer gas composition, with up to 40% and 42.5% faster total ignition time for iso-octane and n-heptane, respectively, by using Ar instead of N₂. The chemical effects of the buffer gas composition were studied experimentally by comparing the results of the N₂ and Ar/CO₂ (65.1%/34.9%) mixtures, recognizing that while the Ar/CO₂ mixture has the same heat capacity as N₂, its predicted combined third-body collision efficiency is about 76% higher than N₂. The experimental results showed negligible chemical effects on the first-stage and total ignition delay times. Numerical simulations were carried out over a wider range of temperatures for pure N₂, Ar, and CO₂ as buffer gases. Results showed that thermal effects are very pronounced and dominated at the negative temperature coefficient and two-stage ignition conditions, which is consistent with the experimental results and previous studies in the literature. However, the simulation results also showed at temperatures higher than 850 K, the chemical effects of CO₂ became more important than the thermal effects.