LED环氧树脂封装材料研究进展

针对封装材料在使用中的缺陷,综述了对环氧树脂的增韧、提高耐热性、改善透明性、改善加工性能的研究现状,并介绍了LED环氧树脂封装材料的发展前景。     

六足气动机器人的结构设计与步态规划

本文设计了一种六足气动机器人,由本体、六条相同的腿部、足部等连接件组成。六条腿部对称呈对称分布与本体两侧。腿部具有柔性关节。通过控制向腿部气橡囊中通入气体的压力及方向的不同,可实现机器人腿部轴向伸缩和弯曲变形。并通过步态规划实现了机器人的前后移动,为气动柔性机器人的研究提供一定的理论基础。     

仪器仪表设备故障诊断

结合实践经验,提出了仪器仪表设备故障诊断的基本思路,并归纳出易引起故障的原因及故障诊断的方法.     

催化加氢法合成苯甲醛研究进展

综述了国内外苯甲酸及其酯催化加氢制备苯甲醛技术的研究进展,并针对当前研究状况,提出了改进办法以及新型苯甲醛生产综合途径。     

Characterization,Expression Profiling,and Biochemical Analyses of the Cinnamoyl-CoA Reductase Gene Family for Lignin Synthesis in Alfalfa Plants

Cinnamoyl-CoA reductase (CCR) is a pivotal enzyme in plant lignin synthesis, which has a role in plant secondary cell wall development and environmental stress defense. Alfalfa is a predominant legume forage with excellent quality, but the lignin content negatively affects fodder digestibility. Currently, there is limited information on CCR characteristics, gene expression, and its role in lignin metabolism in alfalfa. In this study, we identified 30 members in the CCR gene family of Medicago sativa. In addition, gene structure, conserved motif, and evolution analysis suggested MsCCR1–7 presumably functioned as CCR, while the 23 MsCCR-likes fell into three categories. The expression patterns of MsCCRs/MsCCR-likes suggested their role in plant development, response to environmental stresses, and phytohormone treatment. These results were consistent with the cis-elements in their promoters. Histochemical staining showed that lignin accumulation gradually deepened with the development, which was consistent with gene expression results. Furthermore, recombinant MsCCR1 and MsCCR-like1 were purified and the kinetic parameters were tested under four substrates. In addition, three-dimensional structure models of MsCCR1 and MsCCR-like1 proteins showed the difference in the substrate-binding motif H212(X)2K215R263. These results will be useful for further application for legume forage quality modification and biofuels industry engineering in the future.     

工程图档管理系统的开发

描述了工程图档管理系统在企业中的应用和在企业管理系统中的作用,分析了它的功能特点和组成,并简述了用VisualBasic设计开发一个工程图档管理系统的过程。     

Mebendazole-Induced Blood-Testis Barrier Injury in Mice Testes by Disrupting Microtubules in Addition to Triggering Programmed Cell Death

Mebendazole (MBZ) is a synthetic benzimidazole known for its antiparasitic properties. In recent years, growing evidence showed that MBZ was also used as an anti-tumor agent. However, whether (and to what extent) this drug treatment affected the male reproductive system was not well-understood. In this study, male C57BL/6 mice were injected with 40 mg/kg/day of MBZ. The treatment was for 3 and 7 days. Our results showed that the injected mice exhibited an abnormal spermatogenic phase with a significant decrease in sperm. We further detected microtubule disruption and transient functional destruction of the blood–testes barrier (BTB) in the MBZ-injected mice testes (BTB). Our data confirmed that MBZ suppressed the expression of the BTB junction-associated proteins and disrupted the Sertoli cells’ function in vivo. Moreover, MBZ-treated mice demonstrated an aberrant caspase-3 signalling pathway, which resulted in the apoptosis of the germ cells. Here, we present our data, indicating that MBZ impairs BTB by reducing the expression of the microtubules’ and BTB junction-associated proteins. The last leads to activating the caspase-3 pathway, which triggers extensive germ cell apoptosis.     

用核糖体工程技术二次开发海洋微生物菌株资源的研究

经对无活性的海洋来源放线菌B3054进行链霉素抗性筛选,获得了一株具有抗肿瘤活性的链霉素抗性突变株SY-1.从该突变株的发酵物中分离得到了4个活性化合物,其中1个为新天然产物.对该菌株突变前后的rpsL基因(编码核糖体蛋白S12)进行分析未发现发生突变,提示突变位点可能在核糖体的另外亚基上.实验结果表明,核糖体工程技术可用于无活性菌株资源的二次开发利用.