Reactive lesions of the gingiva. A clinicopathological study of 741 cases

A series of 741 consecutive cases of localized hyperplastic lesions of the gingiva were studied. The lesions were reclassified into four groups: pyogenic granuloma, peripheral giant cell granuloma, fibrous hyperplasia and peripheral fibroma with calcification. This study indicates that there are some differences between these groups in age and sex distribution as well as in location and size of the lesion. Fibrous hyperplasia was the most common type, followed in descending order by pyogenic granuloma, peripheral fibroma with calcification and peripheral giant cell granuloma. The peripheral giant cell granuloma showed no sex predilection while fibrous hyperplasia, pyogenic granuloma and peripheral fibroma with calcification were more common in females. Pyogenic granuloma and peripheral fibroma with calcification occur in younger patients more often than fibrous hyperplasia, and thus may represent a stage in the development of fibrous hyperplasia.     

Self-reported mental distress under the shifting daylight in the high north

Our knowledge of airways reactivity to inflammatory agonists is derived predominantly from tests dominated by large airway responsiveness. To determine directly, the histamine responsiveness of the smallest airways, eight normal and 11 asymptomatic asthmatic subjects were studied utilizing a wedged bronchoscope technique. A fiberoptic bronchoscope was wedged in the anterior segment of the right upper lobe and a double-lumen catheter was advanced through the working channel to its tip. With a constant flow of gas (5% CO2 in air) through one lumen of the catheter, pressure at the tip of the bronchoscope was measured with the subject breath-holding at FRC. Peripheral airways resistance (Rp) was measured at baseline and after saline, histamine (10, 50, 100 mg/ml) and isoproterenol (2 mg/ml) challenge through the bronchoscope. Baseline Rp of asthmatics (0.041 +/- 0.015 cm H2O/ml/min; mean +/- SE) was significantly greater than normal subjects (0.011 +/- 0.003 cm H2O/ml/min; p = 0.019). The log of the concentration of histamine that caused a 100% increase in peripheral airways response was greater in the normal subjects than in the asthmatic subjects (p = 0.0114) and correlated with whole lung responsiveness to histamine in asthmatics (r = 0.847, p < 0.05). Isoproterenol reversed completely the increase in Rp in normal subjects but not asthmatic subjects. The results of this study demonstrate that the resistance of the smallest peripheral airways, when measured directly, increased when challenged locally with histamine in both normal subjects and asthmatic subjects. However, the peripheral airways responsiveness was significantly enhanced in asthmatic subjects relative to normal controls.     

Finite element operators: Inexpensive evaluation of upwind schemes

This paper introduces the notion of the finite element operator, and shows its application to the evaluation of several upwind finite element schemes. It is demonstrated that these operators supply good qualitative information on the performance of these schemes in an inexpensive as well as visual manner. In addition, this method gives insight into grid dependent effects which often characterize finite element solutions.     

Adherence-health status relationships in childhood diabetes.

Examined the relationship between adherence (ADH) behavior (to a diabetes regimen) and health status in 78 6–19 yr olds with insulin-dependent diabetes mellitus. 13 ADH measures were grouped into 6 ADH factors (Injection, Exercise, Diet Type, Testing/Eating Frequency, Calories Consumed, and Concentrated Sweets). Prevailing glucose levels were indexed, and fasting triglycerides (TRIG) and total cholesterol (CHOL) assays were used to estimate lipid metabolism. Adolescents were generally less adherent than younger Ss. Only Calories Consumed showed any predictive power. No significant regression equations emerged for CHOL. In contrast, TRIG was significantly associated with most ADH factors; in all cases, ADH interacted with the Ss' metabolic status, suggesting that ADH had different effects for Ss in good vs poor diabetes control. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Therapeutic control of plasma concentrations and long-term effect of nortriptyline in recurrent affective disorders

Based on the evidence that therapeutic plasma concentration range in fact exists for the tricyclic antidepressant drug, Nortriptyline (range 50-150 ng/ml), three different investigations were under taken in order to clarify some clinical pharmacological problems during long-term treatment with this drug. The possible prophlactic effect of the drug in recurrent affective disorders was specially examined in a group of patients with a high risk of episodes in their unipolar manic-depressive disease. The results highly demonstrate the value of monitoring plasma levels in achieving therapeutic control. Depressive relapses during treatment, for months and years, were only related to therapeutic insufficient plasma levels of the drug.     

A direct spectrophotometric determination of butylated hydroxyanisole in lard and in hardened lard

Summary A direct spectrophotometric method for the determination of butylated hydroxyanisole has been presented. This procedure allows good precision in the analysis of lard and hardened lard containing from 0 to 100 p.p.m. of BHA and is more reliable than existing colorimetric techniques, especially in the lower range of antioxidant concentrations.