Revised cutoff values of serum aminotransferase in detecting viral hepatitis among CAPD patients: experience from Taiwan, an endemic area for hepatitis B

BACKGROUND: To determine the best cutoff values of aspartate aminotransferase (AST) and alanine amino-transferase (ALT) in detecting viral hepatitis C infection among patients of continuous ambulatory peritoneal dialysis (CAPD). METHODS: 90 (44 male and 46 female) CAPD patients and 526 adult controls (266 male, 260 female) were enrolled. Serum AST and ALT were measured by an auto-analyser monthly. Serum HBsAg was examined using a RIA method and anti-HCV by an second-generation EIA method. The best cutoff values of AST and ALT for detecting viral hepatitis were obtained from the ROC (receiver-operating characteristic) curve. RESULTS: The prevalence of anti-HCV(+) was significantly higher in CAPD patients (16.7%) than in normal controls (4.9%), while that of HBsAg(+) was similar in both groups. CAPD patients had significantly lower levels of serum aminotransferases compared to normal controls. Mean AST were 23.8 IU/l in normal control and 18.8 IU/l in the CAPD patients (P < 0.001). Mean ALT were 21.9 IU/l in normal controls and 15.3 IU/l in the CAPD patients (P < 0.001). CAPD patients with HCV infection had higher serum AST and ALT levels than those without. However, HBV infection did not cause significant serum aminotransferase elevation in patients. The conventional cutoff values of AST (40 IU/l) and ALT (40 IU/l) for detecting viral hepatitis yielded only a sensitivity of 27.3 and 18.2% respectively; on the contrary, our revised cutoff values of AST (24 IU/l) and ALT (17 IU/l) had better sensitivities (AST, 72.7%; ALT, 63.6%). For serial aminotransferase values, the sensitivity of AST and ALT for detecting HCV were 36.4 and 27.3% by conventional criteria, and were both 81.8%, by our newly revised criteria. CONCLUSIONS: Serum aminotransferase cutoff values should be modified for screening viral hepatitis in a CAPD population. Our new cutoff criteria had important clinical implications in providing benefits of earlier detection and possible prevention from chronic hepatic deteriorations.     

埋地管道涂层检测技术现状

文章对各种埋地管道涂层检测技术进行了综述,并指出了各种技术的优缺点及应用前景.     

移动式宽频带高产额中子发生器

多用途中子发生器有着广阔的市场和应用领域 ,文章对移动式宽频带高产额中子发生器 ,在设计制造过程中所涉及到的技术难点 :绝缘尺寸小、频率适应范围宽、为中子管提供靶压的高压负载特性好等作了技术分析 ,使多用途中子发生器在更广阔的范围内应用 ,提供了广阔前景。     

Handling multimedia information with VLSI

Identifies the basic technological components of multimedia communications. Among these technologies, multimedia processing and transmission already benefit heavily from VLSI advances. in fact, these two technologies could not have matured without special-purpose VLSI chips. We have examined basic processing required in these technologies and some VLSI architectures. The focus has been on standard-compliant VLSI chips, because the eventual goal of communications is to allow everyone to reach others without constraints. There are still a number of evolving standards, which means that we might witness yet another wave of VLSI chips for multimedia communications     

L－B膜修饰电极循环伏安行为模拟──（Ⅰ）电荷转移速度常数对循环伏安性能的影响

本文用计算机数字模拟方法研究了电活性分子多层Ｚ型Ｌ－Ｂ膜修饰电极的循环伏安行为。计算了电极与修饰Ｌ－Ｂ膜分子第一层之间的电荷转移速度常数Ｋ_ｏ，Ｌ－Ｂ膜分子层间的电荷转移速度常数ｋ_ｉ；对峰电位差△Ｅ_ｐ及阳极峰面积Ｑ的影响，以及在不同条件下各层分子的氧化态分数随扫描时间的变化。为研究和设计电活性分子修饰电极的实际体系提供了大量数据和信息。     

单片机仿真系统

本文讨论单片机离线仿真系统的设计方法，其关键技术是：单片机硬件系统（ＲＡＭＲＥＧＩＳＴＥＲＳ）仿真，指令系统仿真，中断系统仿真，应用系统硬件仿真。     

参数化图形库技术

本文论述了参数化图形库的实现原理，建立了以尺寸叠加算法为基础的参数化图形库开发工具，利用这种开发工具建立的图形数据可以由数据库管理，方便有效。     

Windows系统中两种动态交换数据的方法

本文介绍了Ｗｉｎｄｏｗｓ环境下基于消息的ＤＤＥ和基于动态链接库的ＤＤＥＭＬ的区别，并详细叙述了如何使用ＤＤＥＭＬ编制Ｗｉｎｄｏｗｓ应用程序。     

Hierarchical models for analysis and recognition of handwritten characters

Different hierarchical models in pattern analysis and recognition are proposed, based on occurrence probability of patterns. As an important application of recognizing handprinted characters, three typical kinds of hierarchical models such asM _89-89,M _89-36 andM _36-36 have been presented, accompanied by the computer algorithms for computing recognition rates of pattern parts. Moreover, a comparative study of their recognition rates has been conducted theoretically; and numerical experiments have been carried out to verify the analytical conclusions made. Various hierarchical models deliberated in this paper can provide users more or better choices of pattern models in practical application, and lead to a uniform computational scheme (or code). The recognition rates of parts can be improved remarkably by a suitable hierarchical model. For the modelM _89-36 in which case some of the Canadian standard handprinted characters have multiple occurrence probabilities, the total mean recognition rates of the given sample may reach 120% of that by the model proposed by Li et al., and 156% of that obtained from the subjective experiments reported by Suen.     

中国古典园林三维造型研究

论述了采用层次结构化及参数化三维造型方法，建立一个以造型函数库为核心，从而构造各类、各级园林景观构件表面模型的方法和过程。对于某些非建筑类的园林配景构件，采用了Ｆｒａｃｔａｌ方法进行造型。