流体阻尼器粘性发热对整星隔振的影响

在航天器发射过程中,流体粘度随温度变化而改变,流体阻尼器具有不同的阻尼比和共振频率。结合流体阻尼器在整星隔振中的应用,建立发射阶段的热动力学模型。通过数值模拟比较不同粘温系数、不同阻尼器参数下的整星隔振秒特性,并对粘性发热的作用进行了试验研究。理论分析和试验表明,随着时间的推移,阻尼器温度升高,隔振系统的共振频率发生偏移,共振峰值发生变化。     

一种抑制时差法超声流量计静态漂移的方法

时差式超声流量计的静态漂移过大会带来动态计量准确度和精度的下降,对接收到的超声信号的准确判断可以有效抑制静态瞬时流量的漂移.传统的阚值法抗干扰能力比较弱,存在较大的静态漂移,严重影响了流量计精度的提升.文中提出过零阈值平滑模型,对阈值法进行改进.实验证明该方法能够准确判断接收到的超声信号,有效抑制了静态瞬时流量的漂移,提高了计量精度.     

星载-机载混合双站SAR回波信号的仿真

对于星载-机载双站合成孔径雷达（SA-BiSAR）系统,回波模拟的关键是计算出卫星、飞机和目标这三者之间的距离。在考虑地球自转的情况下,提出了用坐标变换的方法,解决了近地空间与外太空之间距离的计算问题,实现了任意几何模型下更为精确的SA-BiSAR回波模拟。同时,利用此方法也可获得直达波信号。点目标的仿真展示了SAR回波信号的特征,该方法得到了验证。     

Roles and Applications of Red Blood Cell-Derived Extracellular Vesicles in Health and Diseases

Red blood cell-derived extracellular vesicles (RBCEVs) are vesicles naturally produced by red blood cells and play multiple roles such as acting as cell-to-cell communication messengers in both normal physiological and diseased states. RBCEVs are highly promising delivery vehicles for therapeutic agents such as biomolecules and nucleic acids as they are easy to source, safe, and versatile. RBCEVs autonomously target the liver and pass the blood–brain barrier into the brain, which is highly valuable for the treatment of liver and brain diseases. RBCEVs can be modified by various functional units, including various functional molecules and nanoparticles, to improve their active targeting capabilities for tumors or other sites. Moreover, the RBCEV level is significantly shifted in many diseased states; hence, they can also serve as important biomarkers for disease diagnoses. It is clear that RBCEVs have considerable potential in multiple medical applications. In this review, we briefly introduce the biological roles of RBCEVs, presented interesting advances in RBCEV applications, and discuss several challenges that need to be addressed for their clinical translation.     

Repetitive Sequence Barcode Probe for Karyotype Analysis in Tripidium arundinaceum

The barcode probe is a convenient and efficient tool for molecular cytogenetics. Tripidium arundinaceum, as a polyploid wild allied genus of Saccharum, is a useful genetic resource that confers biotic and abiotic stress resistance for sugarcane breeding. Unfortunately, the basic cytogenetic information is still unclear due to the complex genome. We constructed the Cot-20 library for screening moderately and highly repetitive sequences from T. arundinaceum, and the chromosomal distribution of these repetitive sequences was explored. We used the barcode of repetitive sequence probes to distinguish the ten chromosome types of T. arundinaceum by fluorescence in situ hybridization (FISH) with Ea-0907, Ea-0098, and 45S rDNA. Furthermore, the distinction among homology chromosomes based on repetitive sequences was constructed in T. arundinaceum by the repeated FISH using the barcode probes including Ea-0663, Ea-0267, EaCent, 5S rDNA, Ea-0265, Ea-0070, and 45S rDNA. We combined these probes to distinguish 37 different chromosome types, suggesting that the repetitive sequences may have different distributions on homologous chromosomes of T. arundinaceum. In summary, this method provide a basis for the development of similar applications for cytogenetic analysis in other species.     

极大节旋藻(Arthrospira maxima)生物钟基因kaiC的克隆及分析

以kaiC基因簇部分已知序列为引物设计位点,采用PCR反应池法从节旋藻基因组fosmid文库中筛选到kaiC基因克隆,通过步移测序获得了kaiC基因全长序列。kaiC基因编码区长1554bo,基因GC碱基含量平均为41．76％,密码子第三位明显偏向于U。在基因上游385bp范围内发现一个可能的启动子序列和一些基因调控元件。KaiC蛋白分析发现了Walker A、DXXG、不完整的Walker B等重要模体和具有催化作用的功能位点。Southem杂交的结果证明kaiC基因在极大节旋藻中为单拷贝。极大节旋藻kaiC基因的特殊结构特征为研究kai基因簇的进化提供了重要的启示。     

Cryogenic Exfoliation of 2D Stanene Nanosheets for Cancer Theranostics

Stanene(Sn)-based materials have been extensively applied in industrial production and daily life,but their potential biomedi-cal application remains largely un...     

基于TMP04的PIC单片机测温实现

数字化温度传感器可以直接将温度量以数字脉冲信号形式输出,具有测量精度高、抗干扰能力强、传输距离远、外围接口电路简单等诸多优点.同时数字温度传感器还可直接与微处理器进行接口,大大方便了传感器输出信号的处理.本文以PWM模式输出的TMP04型数字式温度传感器为例,介绍由PIC单片机实现的几种测温方案,并给出软件设计流程.