A Profile of Psychologists' Views of Critical Risk Factors for Completed Suicide in Older Adults.

The ability to accurately and reliably predict whether an older adult will commit suicide has eluded clinicians and researchers. A random national sample of psychologists who work with older adults was surveyed regarding their perception of 36 risk factors for completed suicide and indirect self-destructive behavior in older adults. This study produced a profile of psychologists' assessment and treatment practices when working with suicidal older adults. Determining what psychologists consider to be the most salient risk factors for completed suicide is important in identifying a minimum standard that clinicians should follow when assessing older adults. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

An intelligent decision theoretic approach to producibility optimization in conceptual design

Product optimization involves selecting design, manufacturing, and support attributes that can produce the best system. Producibility or manufacturability is the term often used to describe the relative ease of manufacturing a product. In complex systems, productibility optimization is a very difficult process, particularly when the values of many attributes are restricted by constraints. One challenge is to develop more universal producibility metrics for the conceptual design phase when design information is limited and drawings are nondimensional. This paper develops a new method for producibility optimization in conceptual design based on a combination of both decision theoretic and expert system techniques. Decision theoretic techniques provide the means to model the design for producibility problem in a manner that can deal with risk, uncertainty, and user (or corporate) preferences, and can effectively integrate diverse factors to provide a measure of the overall worth of a design. The particular decision theoretic approach employed is based on multi-attribute utility theory. An illustrative example of the methodology is applied to the conceptual design of a structural composite part.     

Neuropsychological and psychosocial effects of the FMR-1 full mutation: Case report of monozygotic twins discordant for the fragile X syndrome.

An extensive evaluation was conducted with 16-yr-old monozygotic twins concordant for the fragile X full mutation but discordant for mental retardation. The clearly affected twin had an IQ score of 47; 77% of her neuropsychological z scores were at least 2 SDs below average. Her sister had an IQ score of 105 and average neuropsychological performance. However, each girl demonstrated relative verbal strengths and visual-spatial weaknesses. Their parents rated each girl as having significant problems with attention, conduct, anxiety-withdrawal, and hyperactivity. The girls did not rate themselves as having significant anxiety. These findings are consistent with group data on females with fragile X and demonstrate the wide range of effects associated with the fragile X full mutation. This case report implicates the importance of a psychosocial phenotype of fragile X independent of cognitive ability level. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

How infants perceive a simple causal event.

Four experiments examined 10-mo-old infants' causal event perception. Exp 1 replicated previous studies except that the specific objects used as agent and recipient varied from trial to trial. Under these conditions infants did not process the causality. Instead they keyed on specific temporal and spatial differences among the events. Exp 2 showed that infants notice a change in the particular agent performing either a causal or noncausal action. Exp 3 showed that infants do not notice a change in the type of action done to a particular recipient. Exp 4 demonstrated that infants do not pay attention to the object used as a recipient. As a whole, the results indicate that 10-mo-old infants perceive the causality of simple events by associating a specific agent with the causal action. These results provide more support for an information-processing view than for the view that infants have a causal module. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The location and tracking of swallowed dental appliances: the role of radiology

BACKGROUND: The effects of beta 2 adrenergic agonists on chemoreceptors remain controversial. This study was designed to examine whether fenoterol, a beta 2 adrenergic agonist, increases the ventilatory responses to hypercapnia (HCVR) and hypoxia (HVR) in normal subjects. METHODS: HCVR was tested with a rebreathing method and HVR was examined with a progressive isocapnic hypoxic method in 11 normal subjects. Both HCVR and HVR were assessed by the slope of occlusion pressure (P0.1) or ventilation (VE) plotted against end tidal carbon dioxide pressure and arterial oxygen saturation, respectively. Respiratory muscle strength, spirometric values and lung volume were measured. After a single oral administration of 5 mg fenoterol or placebo HCVR and HVR were evaluated. RESULTS: Fenoterol treatment did not change the specific airway conductance or forced expiratory volume in one second. Respiratory muscle strength did not change. Fenoterol increased the slope of the HCVR of both P0.1 (from 0.251 (0.116) to 0.386 (0.206) kPa/kPa, average increase 71%) and VE (from 10.7 (3.4) to 15.1 (4.2) l/min/kPa, average increase 52%), and shifted the response curves to higher values. For the HVR fenoterol increased the slopes of both P0.1 and VE (from -4.06 (2.00) x 10(-3) to -7.99 (4.29) x 10(-3) kPa/%, an average increase of 83%, and from -0.221 (0.070) to -0.313 (0.112) l/min/%, a 44.5% increase, respectively), and shifted the response curves to higher values. CONCLUSION: Acute administration of fenoterol increases the ventilatory responses to both hypercapnia and hypoxia in normal subjects.     

Effect of titanium substitution on the structure and properties of Fe3Al-based intermetallic alloys

Substitutions (0–16 at%) of titanium for iron in Fe₃Al-based alloys rapidly solidified by chill-block melt-spinning stabilize the D0₃ and B2 ordered structures. Rapid solidification results in total suppression of D0₃ order in binary alloys, whereas alloys containing titanium have D0₃ structure. D0₃ and B2 antiphase domain size, lattice parameter and hardness increase with increasing titanium content of the alloy. The deformation mode changes from single (unit) bcc dislocation in binary alloys to two-fold superdislocation configuration in D0₃Fe₃Al-Ti alloys. Mechanical antiphase boundaries are generated by the movement of these imperfect configurations. All the alloys exhibited cleavage tensile failure. The mechanical properties are correlated with the observed structural changes.     

Egg Thiamine Status of Lake Ontario Salmonines 1995–2004 with Emphasis on Lake Trout

Alewives (Alosa pseudoharengus), the major prey fish for Lake Ontario, contain thiaminase. They are associated with development of a thiamine deficiency in salmonines which greatly increases the potential for developing an early mortality syndrome (EMS). To assess the possible effects of thiamine deficiency on salmonine reproduction we measured egg thiamine concentrations for five species of Lake Ontario salmonines. From this we estimated the proportion of families susceptible to EMS based on whether they were below the ED20, the egg thiamine concentration associated with 20% mortality due to EMS. The ED20s were 1.52, 2.63, and 2.99 nmol/g egg for Chinook salmon (Oncorhynchus tshawytscha), lake trout (Salvelinus namaycush), and coho salmon (Oncorhynchus kisutch), respectively. Based on the proportion of fish having egg thiamine concentrations falling below the ED20, the risk of developing EMS in Lake Ontario was highest for lake trout, followed by coho (O. kisutch), and Chinook salmon, with the least risk for rainbow trout (O. mykiss). For lake trout from western Lake Ontario, mean egg thiamine concentration showed significant annual variability during 1994 to 2003, when the proportion of lake trout at risk of developing EMS based on ED20 ranged between 77 and 100%. Variation in the annual mean egg thiamine concentration for western Lake Ontario lake trout was positively related (p < 0.001, r² = 0.94) with indices of annual adult alewife biomass. While suggesting the possible involvement of density-dependent changes in alewives, the changes are small relative to egg thiamine concentrations when alewife are not part of the diet and are of insufficient magnitude to allow for natural reproduction by lake trout.     

Peristaltic pumping of solid particles

We simulate solid particle transport by peristalsis in a two-dimensional channel with sinusoidal waves. The fluid is regarded as viscous and incompressible, and the walls of the channel and the particle as neutrally buoyant elastic boundaries immersed in this fluid. Using the immersed boundary technique, we are able to computationally model fluid-particle interaction. To demonstrate the validity of our computational approach, we first present results of computations without solid particles and compare them with existing theory and computations. We then examine how the transport of the solid particle depends upon its diameter, the Reynolds number and its initial placement in the channel. We also present evidence that the mean transport speed of a particle increases geometrically as its diameter approaches the channel width.     

Hot-drawing of poly(methyl methacrylate) and simulation using a glass-rubber constitutive model

The large-deformation three-dimensional glass-rubber constitutive model for isotropic, amorphous, linear polymers near the glass transition, previously proposed, has been extended to include a spectrum of network relaxations. In addition, an experimental programme of uniaxial tension and compression tests was carried out on high molecular weight cast sheets of poly(methyl methacrylate) (PMMA), with varying strain-rate and temperature across the range from 114 to 190 °C, encompassing the thermoforming range of practical importance. The extended model was found to fit successfully the data for PMMA, provided a doublet network relaxation spectrum was employed. The original model, with only a single network relaxation, was found to be grossly inadequate when there was significant network relaxation by entanglement slippage. Parameters of the model for PMMA, obtained by fitting to the new data, were compared with values obtained by other routes.