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51.
A major problem in the design and manufacturing of surface mounted permanent magnet machines is reliably holding the permanent magnets in place at high speeds. This paper evaluates a unique rotor lamination design for a high pole number, permanent magnet alternator. This buried magnet design, which is capable of reliably holding the permanent magnets in place at high speeds, offers both easier and cheaper assembly when compared with the methods currently used in surface mounted permanent magnet machines. Finite element analysis is used to compare the buried magnet design with equivalent surface mounted designs and shows that the performance of the alternator is not significantly affected by the iron over the magnets. Experimental results from a prototype alternator further corroborate the FEA and show that the design is capable of operating at high speeds with no other means of magnet retention. In addition, an improvement in the buried magnet design which can reduce the lamination complexity is suggested and examined  相似文献   
52.
This paper presents a synchronous frame flux-based control method for a parallel active filter application. The flux-based controller directly implements the inverter switchings in the synchronous reference frame by a hysteresis rule-based carrier-less pulse-width modulation (PWM) strategy to achieve high current bandwidth. This paper addresses the issues and impact on parallel active filtering requirements for utility interface of commonly used harmonic front-ends. The synchronous frame flux-based controller provides additional insights for harmonic current compensation requirements. Simulation results provide the validation of the flux-based active filter controller to meet IEEE Standard 519 recommended harmonic standards for large rated nonlinear loads under balanced and unbalanced supply conditions  相似文献   
53.
We present thermal expansion measurements on a La1.85Sr0.15CuO4 single crystal in external magnetic fields. Clear anomalies of the thermal expansion are observed at the superconducting transition. We have studied in detail the anisotropic influence of external fields on the anomalies. As expected, the field dependence is maximum for B c and minimum for B c. The measured angular dependence corresponds to that of an anisotropic 3d superconductor with an anisotropy parameter 18.  相似文献   
54.
R. Todd Lorenz  L. W. Parks 《Lipids》1991,26(8):598-603
There is an intimate association between sterol biosynthesis in yeast and aerobicity. Besides the requirement for molecular oxygen for the epoxidation of squalene, cytochrome hemoproteins are involved in demethylation and desaturation steps. Regulatory effects of hemes on sterol formation have been demonstrated using specifically defective mutants of yeast. Heme competency participates in a mechanism whereby wild-type cells are prevented from taking exogenous sterols from the growth media. The multiple interactions of hemes and sterols appear to be associated with the variously defined functions for sterols in the yeast cells. Based on a paper presented at the Symposium on Plant and Fungal Sterols: Biosynthesis, Metabolism and Function, held at the AOCS Annual Meeting, Baltimore, MD, April 1990.  相似文献   
55.
The effective clinical use of the anticancer drug 5-fluorouracil (5-FU) requires the non-invasive assessment of its transport and metabolism, particularly in the tumor and the liver, where the drug is catabolized to alpha-fluoro-beta-alanine (FBAL). In this study, the potentials and limitations of dynamic 18F PET and metabolic 19F MRI examinations for noninvasive 5-FU monitoring were investigated in ACI and Buffalo rats with transplanted MH3924A and TC5123 Morris hepatomas, respectively. Selective 5-[19F]FU and [19F]FBAL MR images were acquired 5 and 70 min after 5-FU injection using a CHESS MRI sequence. After administration of 5-[18F]FU, the kinetics of the regional 5-[18F]FU uptake were measured by dynamic PET scanning over 120 min. To allow a comparison between PET and MRI data, standardized uptake values (SUV) were computed at the same points in time. The TC5123 hepatoma showed a significantly (p < 0.002) higher mean SUV at 5 and 70 min post-5-FU injection than the MH3924A cell lines, whereas there were no significant differences between the mean SUV measured in the liver of both animal populations. In contrast to the PET data, no significant differences in the mean 5-[19F]FU and [19F]FBAL MR signal values in the tumor of both models were observed. The MR images, however, yielded the additional information that 5-FU is converted to FBAL only in the liver and not in the hepatomas.  相似文献   
56.
57.
Nitrogen-starved diploid cells of the yeast Saccharomyces cerevisiae differentiate into a filamentous, pseudohyphal growth form. Recognition of nitrogen starvation is mediated, at least in part, by the ammonium permease Mep2p and the Galpha subunit Gpa2p. Genetic activation of the pheromone-responsive MAP kinase cascade, which is also required for filamentous growth, only weakly suppresses the filamentation defect of Deltamep2/Deltamep2 and Deltagpa2/Deltagpa2 strain. Surprisingly, deletion of Mep1p, an ammonium permease not previously thought to regulate differentiation, significantly enhances the potency of MAP kinase activation, such that the STE11-4 allele induces filamentation to near wild-type levels in Deltamep1/Deltamep1 Deltamep2/Deltamep2 and Deltamep1/Deltamep1 Deltagpa2/Deltagpa2 strains. To identify additional regulatory components, we isolated high-copy suppressors of the filamentation defect of the Deltamep1/Deltamep1 Deltamep2/Deltamep2 mutant. Multicopy expression of TEC1, PHD1, PHD2 (MSS10/MSN1/FUP4), MSN5, CDC6, MSS11, MGA1, SKN7, DOT6, HMS1, HMS2, or MEP2 each restored filamentation in a Deltamep1/Deltamep1 Deltamep2/Deltamep2 strain. Overexpression of SRK1 (SSD1), URE2, DAL80, MEP1, or MEP3 suppressed only the growth defect of the Deltamep1/Deltamep1 Deltamep2/Deltamep2 mutant strain. Characterization of these genes through deletion analysis and epistasis underscores the complexity of this developmental pathway and suggests that stress conditions other than nitrogen deprivation may also promote filamentous growth.  相似文献   
58.
Corrosion systems exhibiting discontinuous anodic polarization curves have been investigated by steady state polarization, linear sweep polarization, large and small signal pulse polarization, a.c. impedance measurements and solution analysis. It is shown that the true corrosion current density can only be determined if the non-linearity of the system is avoided. This is not possible from analysis of a.c. impedance results without model assumptions.  相似文献   
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60.
Burnout is generally defined as a state of severe exhaustion. So far, research has predominantly focused on relatively mild burnout in employees able to work despite their complaints. This study examines energy depletion in clinical burnout (e.g., the severest cases on extended sick leave) by comparing the diurnal patterns of fatigue and exhaustion with those of healthy individuals. Sixty clinically burned-out and 40 healthy participants kept an electronic diary for 14 days, 7 times a day, yielding a total of 8,116 diary entries. This study shows that burned-out individuals typically suffer continuously from a severe fatigue throughout the day. The resulting flattened diurnal cycles mark a stable exhaustion that is uncommon in healthy persons. The current results provide novel support for the existence of severe energy erosion in clinical burnout. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   
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