Turing's three philosophical lessons and the philosophy of information

In this article, I outline the three main philosophical lessons that we may learn from Turing's work, and how they lead to a new philosophy of information. After a brief introduction, I discuss his work on the method of levels of abstraction (LoA), and his insistence that questions could be meaningfully asked only by specifying the correct LoA. I then look at his second lesson, about the sort of philosophical questions that seem to be most pressing today. Finally, I focus on the third lesson, concerning the new philosophical anthropology that owes so much to Turing's work. I then show how the lessons are learned by the philosophy of information. In the conclusion, I draw a general synthesis of the points made, in view of the development of the philosophy of information itself as a continuation of Turing's work.     

Antimicrobial packaging based on ɛ‐polylysine bioactive film for the control of mycotoxigenic fungi in vitro and in bread

?‐Poly‐l‐ lysine (?‐PL) is a cationic peptide with a broad‐spectrum antimicrobial activity. This study investigates the use of ?‐PL as natural antimicrobial to inhibit fungal growth and to reduce aflatoxins (AFs) production. Antifungal activity of starch biofilms with different concentrations of ?‐Poly‐l‐ lysine (?‐PL) was determined in solid medium against Aspergillus parasiticus (AFs producer) and Penicillium expansum. Then, biofilms were tested as antimicrobial devices for the preservation of bread loaf inoculated with A. parasiticus CECT 2681 and P. expansum CECT 2278. Shelf life and AFs content were examined. Biofilms with concentrations of ?‐PL less than 1.6 mg/cm² showed no fungal growth inhibition in solid medium, while the antifungal activity of the films with greater than 1.6 mg/cm² of ?‐PL was dose dependent. The shelf life of bread inoculated with A. parasiticus was increased by 1 day with the use of films containing 1.6–6.5 mg ?‐PL/cm², while shelf life of bread tainted with P. expansum was increased by 3 day with 6.5 mg ?‐PL/cm². AFs production was greatly inhibited by ?‐PL biofilms (93–100%). Thus, ?‐PL biofilms could be potentially used as antimicrobial device during bread storage as a natural alternative to the synthetic preservatives.

Practical applications

?‐Polylysin is a natural substance from microbial metabolism. Polylysine has a function to prevent a microbe from proliferating by ionic adsorption in the microbe. ?‐polylysine has a wide antibacterial spectrum and has an obvious lethal effect on Gram‐positive and Gram‐negative bacteria, yeast, mold, viruses, etc. It has a good antibacterial effect on the Gram‐negative bacteria E. coli and Salmonellae, which are difficult to control with other natural preservatives. ?‐Polylysine has already been used generally as a food additive in Japan, Korea and other part of world. In the United States, FDA has recognized the polylysine as a GRAS material. Considered the positive results obtained in the study, this compound could be used for the production of antimicrobial biofilms, applied as separator slices in the loaf bread production, to prevent the growth of the mycotoxigenic fungi A. parasiticus and P. expansum, contributing to reduce the use of the synthetically preservatives in bakery industry and also of the negative impact that these compounds could generate on the health of the end users.     

Ferritic stainless steel welding with the A-TIG process

The main advantage of the TIG with flux process (A-TIG welding) is the possibility of obtaining greater penetration of the weld bead while employing the same welding parameters as conventional TIG welding. Various studies have shown the influence of active fluxes on the geometric characteristics of stainless steel austenitic welds. However, little is known about the influence of this process on the geometric and metallurgical characteristics of the weld beads in ferritic stainless steels. In this work, different types of flux are applied when welding ferritic stainless steel with the objective of verifying possible influences on the weld bead's profile, on its visual appearance, on the microstructure, on the hardness of the welded zone and on the impact resistance (Charpy test). The bead-on-plate welds were produced without using any addition metal. Six types of flux were used – one being an oxide produced in a laboratory (TiO₂) and five commercial fluxes. The results showed that use of the flux allows an increase in penetration with significant changes in the appearance of the weld bead. It was also confirmed that the microstructure and the hardness of the weld bead for the steel studied were not affected by the type of flux used, with the microstructure analysed under an optical microscope. The steel in the study showed a high degree of fragility at ambient temperature.     

A portable wireless biometric multi-channel system

This article presents an 8-channel system for capturing bioelectric signals and transmitting them by the ZigBee protocol. It is a small, portable system with optimised power supply so that it can be battery fed. One of its main advantages is its versatility, since it enables each channel to be configured, in a dynamic and individualised way. This makes it possible to capture diverse bioelectric signals simultaneously, such as electrocardiogram (ECG), electroencephalogram (EEG), electrooculogram (EOG), etc. The developed system can be easily integrated into a Wireless Sensor Network based on ZigBee technology.     

Isolation and Characterization of Microsatellite Markers for Passiflora contracta

Passiflora contracta Vitta (Passifloraceae) is an endemic species of the Atlantic Rainforest, one of the most species-rich ecoregions in the world, although extremely endangered. We have developed an enriched microsatellite library in order to fine-scale studies of the genetic structure of P. contracta. Twelve pairs of microsatellite primers were designed, and seven loci were successfully amplified and characterized by genotyping two wild populations of P. contracta. All seven loci were polymorphic, with an average number of alleles found being 4.8 and 5 per population. The cross-species transferability was tested using sister species Passiflora ovalis Vell. Ex Roemer. The development of these markers will contribute to the studies of population genetics in P. contracta as well as future studies concerning diversity patterns in the Atlantic Rainforest, and may also help to establish strategies for the conservation of this species.     

Iron reduction potentiates hydroxyl radical formation only in flavonols

Flavonoids, substantial components of the human diet, are generally considered to be beneficial. However, they may possess possible pro-oxidative effects, which could be based on their reducing potential. The aims of this study were to evaluate the ability of 26 flavonoids to reduce ferric ions at relevant pH conditions and to find a possible relationship with potentiation of hydroxyl radical production. A substantial ferric ions reduction was achieved under acidic conditions, particularly by flavonols and flavanols with the catecholic ring B. Apparently corresponding bell-shaped curves displaying the pro-oxidant effect of flavonols quercetin and kaempferol on iron-based Fenton reaction were documented. Several flavonoids were efficient antioxidants at very low concentrations but rather inefficient or pro-oxidative at higher concentrations. Flavonols, morin and rutin were progressively pro-oxidant, while 7-hydroxyflavone and hesperetin were the only flavonoids with dose-dependent inhibition of hydroxyl radical production. Conclusively, administration of flavonoids may lead to unpredictable consequences with few exceptions.