Fabrication of microstructures on different materials by diode-pumped solid state laser writing for microfluidics applications

Laser writing attached many attentions for fabrication micro-channels in microfluidics devices and lab-on-chip devices for biomedical applications. In this study, micro-channels were fabricated on different materials as masters using nanosecond diode-pumped solid state (DPSS) laser writing for imprinting on glass and polymer microfluidics devices. Good quality microstructures were fabricated on silicon, nickel alloy, cooper/brass and alumina, respectively by laser writing which proved that the nanosecond DPSS laser is suitable for rapid prototyping and rapid manufacturing of surface microstructures on different substrates as mask-less exposure system of imprinting.     

Sex-Related Differences in Murine Models of Chemically Induced Pulmonary Fibrosis

We developed two models of chemically induced chronic lung injury and pulmonary fibrosis in mice (intratracheally administered hydrochloric acid (HCl) and intratracheally administered nitrogen mustard (NM)) and investigated male–female differences. Female mice exhibited higher 30-day survival and less weight loss than male mice. Thirty days after the instillation of either HCl or NM, bronchoalveolar lavage fluid displayed a persistent, mild inflammatory response, but with higher white blood cell numbers and total protein content in males vs. females. Furthermore, females exhibited less collagen deposition, milder pulmonary fibrosis, and lower Ashcroft scores. After instillation of either HCl or NM, all animals displayed increased values of phosphorylated (activated) Heat Shock Protein 90, which plays a crucial role in the alveolar wound-healing processes; however, females presented lower activation of both transforming growth factor-β (TGF-β) signaling pathways: ERK and SMAD. We propose that female mice are protected from chronic complications of a single exposure to either HCl or NM through a lesser activation of TGF-β and downstream signaling. The understanding of the molecular mechanisms that confer a protective effect in females could help develop new, gender-specific therapeutics for IPF.     

3D Face Recognition Using Simulated Annealing and the Surface Interpenetration Measure

This paper presents a novel automatic framework to perform 3D face recognition. The proposed method uses a Simulated Annealing-based approach (SA) for range image registration with the Surface Interpenetration Measure (SIM), as similarity measure, in order to match two face images. The authentication score is obtained by combining the SIM values corresponding to the matching of four different face regions: circular and elliptical areas around the nose, forehead, and the entire face region. Then, a modified SA approach is proposed taking advantage of invariant face regions to better handle facial expressions. Comprehensive experiments were performed on the FRGC v2 database, the largest available database of 3D face images composed of 4,007 images with different facial expressions. The experiments simulated both verification and identification systems and the results compared to those reported by state-of-the-art works. By using all of the images in the database, a verification rate of 96.5 percent was achieved at a False Acceptance Rate (FAR) of 0.1 percent. In the identification scenario, a rank-one accuracy of 98.4 percent was achieved. To the best of our knowledge, this is the highest rank-one score ever achieved for the FRGC v2 database when compared to results published in the literature.     

A fast time-domain algorithm for the simulation of switching powerconverters

An efficient algorithm for the simulation of switched-mode power converters is developed. A Chebyshev series expansion is used to effectively solve the differential equations describing the system in each topology. The power of the new simulation technique lies both in the simple, but accurate, polynomial approximation for the state transition matrices and in the ability to explicitly obtain the instants at which the switching of the circuit topology takes place. The simulation technique is illustrated with reference to a simple Buck converter operating at a constant frequency. The derivation of the new algorithm is presented and its performance is analyzed. The case of a rapidly varying input forcing function is analyzed. Examples illustrating the generality and the computational efficiency of the algorithm are presented     

Thermo-Elastic Dynamic Instability (TEDI)—a review of recent results

Frictional instabilities arise in a number of engineering and scientific contexts, when the presence of friction renders unstable the uniform motion between parts under nominally uniform conditions. Various classes of friction instabilities exist, those involving friction weakening with speed, and those at constant coefficient of friction. In the latter class, in turn, there are Dynamic Instabilities (DI) and Thermo-Elastic Instabilities (TEI). Recently, by including inertia terms in the formulations of the simple models already studied, the merging of TEI and DI has shown that, although the coupling of dynamic and thermal terms is generally weak (given the significant difference in the typical time scales of the two processes), thermal effects are capable of making otherwise neutrally stable dynamic modes unstable, rendering the new form of instability TEDI (ThermoElastoDynamic Instability) potentially interesting in a number of applications. Some results involving 1D and 2D models of TEDI are reviewed.     

Color‐separating backlight for improved LCD efficiency

Abstract— A large part of the light generated in a backlight is usually absorbed in the color filters of the liquid‐crystal display. A new backlight system that uses a grating to split the white light into different colors and a lens array to focus this light onto the pixels is presented. The absorbing filters can be eliminated and efficiency is improved. The system is characterized, as well as its different components.