Computer-assisted design and synthesis of a highly selective smart adsorbent for extraction of clonazepam from human serum

A computational approach was applied to screen functional monomers and polymerization solvents for rational design of molecular imprinted polymers (MIPs) as smart adsorbents for solid-phase extraction of clonazepam (CLO) form human serum. The comparison of the computed binding energies of the complexes formed between the template and functional monomers was conducted. The primary computational results were corrected by taking into calculation both the basis set superposition error (BSSE) and the effect of the polymerization solvent using the counterpoise (CP) correction and the polarizable continuum model, respectively. Based on the theoretical calculations, trifluoromethyl acrylic acid (TFMAA) and acrylonitrile (ACN) were found as the best and the worst functional monomers, correspondingly. To test the accuracy of the computational results, three MIPs were synthesized by different functional monomers and their Langmuir–Freundlich (LF) isotherms were studied. The experimental results obtained confirmed the computational results and indicated that the MIP synthesized using TFMAA had the highest affinity for CLO in human serum despite the presence of a vast spectrum of ions.     

Characteristics of X-ray Hot Spots in a 3.5 kJ Plasma Focus Device at Different Pressures of Argon and Air

The present study examined the formation of hot spots in the plasma column of a 3.5 kJ Mather-type plasma focus device. Experiments were performed with air and argon as operating gases at 0.2–1.5 mbar of pressures. X-ray source images were obtained using a pinhole camera with dental X-ray film as X-ray detector. The objective was to investigate the effect of the operating conditions and gas type on formation and characteristics of the hot spots. Results showed that when using air in comparison to argon, the total X-ray emission is increased and therefore, the hot spots are covered by this high intensity emission and would be observed less frequently in the image. Using metal filters to attenuate the low-energy X-rays revealed that the most energetic or the most intense radiation was emitted from the hot spots region. The images of the X-ray source obtained using argon at the middle pressures (0.4–0.6 mbar) showed both the plasma column and the photons emitted from the anode surface. A pressure of 0.8–1.5 mbar using argon was most likely to observe the hot spots. For argon gas, the 0.9 mbar was the pressure in which the hot spots were more frequently observed with high reproducibility of location and number. Measurements revealed that the typical size of a hot spot was 10–300 µm and the distance from the anode surface was 0.5–20 mm.     

Simulating Unsaturated Zone of Soil for Estimating the Recharge Rate and Flow Exchange Between a River and an Aquifer

Coupling surface water and groundwater models dynamically based on a simultaneous simulation of saturated and unsaturated zones of soil is a useful method for determining the recharge rate and flow exchange between a river and an aquifer as well as simultaneous operation of water resources systems. Thus, the main objectives of this study are to investigate the effects of surface water and groundwater interactions through their systematic simulation and to create a dynamic coupling between surface water and groundwater resources of the area by relevant mathematical models. Accordingly, hydrologic soil moisture method and MODFLOW model were employed to simulate the unsaturated and saturated zones, respectively. The results revealed that simultaneous simulation of the saturated and unsaturated zones of the soil can illustrate the interaction between surface water and groundwater at any spatial and temporal intervals well through using complete hydroclimatological balance components in the form of a coupled model. The application of this method in the Loor-Andimeshk Plain, located in the southwest of Iran, showed that aquifer recharge through the plain area from November to March is due to precipitation. On the other hand, in the warm months (June to September), the plain is merely fed through irrigation water penetration. As the level of river water in both Dez and Balarood rivers is higher than the Loor-Andimeshk aquifer level, hence the exchange occurs as a leakage from the river to the aquifer. The highest and lowest values of average exchangeable water in Balarood River occur in March and April and in Dez River are from June to September.

     

Determination of height distribution on a rough interface by measuring the coherently transmitted or reflected light intensity

In this work it is shown theoretically and examined experimentally that the measurement of coherently transmitted or reflected monochromatic light intensity from a randomly rough interface as a function of incident angle provides the height distribution on the interface. It is also shown that the spectrum of coherently transmitted or reflected light from a rough interface is modified and the modified spectrum yields the height distribution. The experimental results obtained by applying both methods, in transmission and reflection, on rough surfaces prepared by roughening the sheet glasses by powders of different grain sizes are quite consistent. In addition, the effect of the surrounding medium's refractive index on the roughness measurement is studied by immersing the samples into liquids of different refractive indices. Also, the application range and limitations of the introduced methods are discussed.     

Effects of Packaging Materials,Modified Atmospheric Conditions,and Storage Temperature on Physicochemical Properties of Roasted Pistachio Nut

Pistachio is one of the most important non-oil export items for Iran and also has the ability to adapt itself to adverse conditions including salinity, moisture stress, soil, and low water irrigation. It is one of the economical crops of desertic and dry areas and is recommended for such places. In this research, the effect of different packaging materials including five layers of compound film, modified polypropylene and metallized plastic, and packaging atmosphere on the quality of roasted pistachio nut were investigated. Atmospheric conditions were N₂/CO₂, vacuum, and ambient air at temperatures of 20 °C and 40 °C. Samples were tested in defined time intervals and then data were statistically analyzed. Results showed that packaging pistachio nut in metallized film and five-layer films with gases N₂/CO₂ and vacuum conditions kept the quality of pistachio better and lengthened shelf-life. A temperature of 40 °C compared to 20 C was a favorable condition for pistachio quality.     

Fabrication of nanostructured and multicompartmental fabrics based on electrospun nanofibers

The fabrication of novel multilayer electrospun nanofiber web is demonstrated. Under optimized processing conditions, the interface between these webs can be sustained for long time, yielding layers with distinct compartments. Simultaneous control over internal fiber architecture makes these multilayer nano-webs potential candidates for applications such as clothing and industrial filters.     

A study on the effects of laminating temperature on the polymeric nanofiber web

The use of fine fiber has become an important design tool for filter media. Nanofibers-based filter media have some advantages such as lower energy consumption, longer filter life, high filtration capacity, easier maintenance, low weight rather than other filter media. The nanofibers-based filter media made up of fibers of diameter ranging from 100 to 1,000 nm can be conveniently produce by electrospinning technique. Common filter media have been prepared with a layer of fine fiber on typically forming the upstream or intake side of the media structure. The fine fiber increases the efficiency of filtration by trapping small particles, which increases the overall particulate filtration efficiency of the structure. Improved fine fiber structures have been developed in this study in which a controlled amount of fine fiber is placed on both sides of the media to result in an improvement in filter efficiency and a substantial improvement in lifetime. In the first part of this study, the production of electrospun nanofibers is investigated. In the second part, a different case studyis presented to show how they can be laminated for application as filter media. Response surface methodology (RSM) was used to obtain a quantitative relationship between selected electrospinning parameters and average fiber diameter and its distribution.