Carbohydrate tolerance in the puerperium during suppression of lactation with bromocriptine and oestrogens

The influence of bromocriptine on carbohydrate tolerance in the puerperium was examined and its effects compared with those of an oestrogenic compound. Sixteen patients were studied in each group. The controls consisted of 16 women who were breast-feeding. Compared with the controls, no significant difference was found in the oral glucose tolerance test in patients who had oestrogen, but blood glucose values in women receiving bromocriptine were significantly lower. Inhibition of lactation with bromocriptine may obscure abnormal glucose tolerance.     

Hospital resource consumption among older adults: a prospective analysis of episodes, length of stay, and charges over a seven-year period

After linking their administrative records and interview data, the consumption of Medicare-reimbursed hospital resources during 1984 through 1990 by the 7,527 LSOA respondents was prospectively assessed using a two-part design. First, logistic regression was used to model whether a hospital episode occurred. Second, among those having had hospital episodes, OLS regression was used to model the number of episodes, as well as the natural logarithms of the total length of stay and the total charges. The risk of hospitalization was mostly associated with being male, prior hospital and physician utilization, and lower body limitations. Among those hospitalized: (a) greater numbers of episodes were mostly associated with prior hospital and physician utilization, and poorer perceived health; (b) longer lengths of stay were mostly associated with prior hospital and physician utilization, and poorer perceived health; and, (c) higher charges were mostly associated with population density, poorer perceived health, and prior physician and hospital utilization. Decedents consistently consumed substantially more hospital resources than survivors.     

Cephalic tetanus: demonstration of a dual lesion

A clinical and electrophysiological study of 15 cases of cephalic tetanus is reported. This condition is a form of local tetanus which commonly follows an injury to the face or head. It is characterised by muscle paralysis which is maximal close to the site of injury, while spasm is evident at mroe distant sites. As muscle paralysis improves with time it is succeeded by spasm. It is argued that paralysis is due to high local concentrations of toxin in the brainstem while lesser concentrations cause spasm by abolishing inhibition. Electrophysiological studies indicate that paralysis is of lower motor neurone type with denervation potentials, hyperirritability, loss of motor units, and marginally increased distal latencies being the features recorded.