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Short communication: Effects of subacute ruminal acidosis on free-choice intake of sodium bicarbonate in lactating dairy cows

The effect of inducing subacute ruminal acidosis (SARA) on the free-choice intake of sodium bicarbonate (SB) was investigated in four midlactation Holstein cows in a switchover experiment with four 1-wk periods. The SARA was induced by replacing 25% of the ad libitum intake of total mixed ration (TMR) with pellets containing 50% ground wheat and 50% ground barley and restricting access to TMR from 0700 to 1700 h. Control consisted of feeding TMR ad libitum. Powdered SB was provided for ad libitum consumption. Rumen pH was measured continuously using indwelling pH probes. Induction of SARA reduced (P < 0.05) the average daily rumen pH from 6.08 to 5.87, increased (P < 0.05) the average duration of rumen pH below 6 from 547 min x d(-1) to 916 min x d(-1), and increased (P < 0.05) the average duration of rumen pH below 5.6 from 132 min x d(-1) to 397 min x d(-1) (P < 0.05) but did not significantly affect SB intake. Average intake of SB was 26.8 g x d(-1) during SARA and 34.5 g x d(-1) during control. These low SB intakes must not have substantially affected rumen pH. Sodium bicarbonate intake differed significantly (P < 0.05) between cows. These data indicate that cows did not select SB in order to attenuate SARA.     

Assembly of Copper Column Interconnect Flip Chip

This paper addresses a new flip chip interconnection technology, flexible flip chip connection (F2C2) technology, for attaching silicon chips to a chip carrier using flexible copper wires. F2C2 is a novel approach to create area array flip chip interconnections using a matrix block of wires encapsulated with a heat-resistant, dissolvable substance. A slice from the wire matrix ingot is first attached to the chip using solder. The other end of the slice is then matched and soldered to the footprint of a substrate. Finally, the encapsulating, dissolvable substance is removed from the body of the slice, leaving the chip attached to the carrier by the inter- disposed, flexible copper wires. The compliant copper wire interconnections can accommodate the coefficient of thermal expansion (CTE) mismatch problem between die and substrate, thus eliminating the need for underfill.     

Exploring mathematical approximation for the time spans of transfer operations in parcel transshipment terminals

The parcel delivery industry (PDI) is a very labor intensive industry, from the drivers of the pickup and delivery vans, to the unloaders, sorters, and loaders in the transshipment terminals. The labor efficiency is a key performance measure in the PDI. In this study, the focus is on developing a framework for improving labor efficiencies in a parcel transshipment terminal. The objective is to minimize the time required to transfer parcels from inbound trailers to outbound trailers. This paper is an exploratory study to developing a framework for a solution approach to solve large-scale parcel hub scheduling problems (PHSP). A binary integer programming (BIP) model is proposed along with a branch and bound (BaB) algorithm with lower and upper bounds. The computational study shows that the BaB algorithm is able to generate solutions for small-size problems. The proposed BIP model sets the ground work for developing solution approaches to much larger size problems.     

Ethology and comparative psychology.

An analysis of the relationship between ethology and comparative psychology is presented by an ethologist whose background was in agriculture, animal breeding, and evolutionary genetics. The view is presented that today, comparative psychology is largely an American name for the ethological work taking place in psychology departments throughout the world. Generally, those studying animal behavior or human ethology fill an important niche in psychology departments, providing the biological, particularly the evolutionary, complement to other fields of psychology. This role is functional, rather than having a theoretical foundation different from ethology. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The importance of generalizability for anomaly detection

In security-related areas there is concern over novel “zero-day” attacks that penetrate system defenses and wreak havoc. The best methods for countering these threats are recognizing “nonself” as in an Artificial Immune System or recognizing “self” through clustering. For either case, the concern remains that something that appears similar to self could be missed. Given this situation, one could incorrectly assume that a preference for a tighter fit to self over generalizability is important for false positive reduction in this type of learning problem. This article confirms that in anomaly detection as in other forms of classification a tight fit, although important, does not supersede model generality. This is shown using three systems each with a different geometric bias in the decision space. The first two use spherical and ellipsoid clusters with a k-means algorithm modified to work on the one-class/blind classification problem. The third is based on wrapping the self points with a multidimensional convex hull (polytope) algorithm capable of learning disjunctive concepts via a thresholding constant. All three of these algorithms are tested using the Voting dataset from the UCI Machine Learning Repository, the MIT Lincoln Labs intrusion detection dataset, and the lossy-compressed steganalysis domain. Gilbert “Bert” Peterson is an Assistant Professor of Computer Engineering at the Air Force Institute of Technology. Dr. Peterson received a BS degree in Architecture, and an M.S. and Ph.D. in Computer Science at the University of Texas at Arlington. He teaches and conducts research in digital forensics and artificial intelligence. Brent McBride is a Communications and Information Systems officer in the United States Air Force. He received a B.S. in Computer Science from Brigham Young University and an M.S. in Computer Science from the Air Force Institute of Technology. He currently serves as Senior Software Engineer at the Air Force Wargaming Institute.     

Treatment of dairy cows with recombinant bovine somatotropin: genetic and phenotypic aspects

Thirty-four multiparous and primiparous Holstein cows were utilized to examine the association between the response to long-term administration of recombinant bovine somatotropin and the cow's phenotypic and genetic production potential. Cows representing a range of phenotypic and genetic production potentials were assigned to one of four treatment groups: 0, 12.5, 25.0, or 50.0 mg recombinant bovine somatotropin daily. They were injected daily for 266 d beginning on d 24 to 35 postpartum. Pretreatment milk and fat yields were used to predict daily yields over the lactation and allowed treatment groups to serve as their own controls. Actual minus predicted yield estimated the response to treatment for milk, fat, and FCM for each cow. Milk composition (fat, protein, and lactose percentage) was not significantly affected by treatment. Response in yield for milk, fat, and FCM was significant during the treatment period (266 d). Milk yield increased by 18.5, 19.9, and 21.4%; fat yield increased by 13.4, 20.3, and 18.1%; and FCM increased by 16.3%, 19.7%, and 21.1% after receipt of 12.5, 25.0 and 50.0 mg recombinant bovine somatotropin, respectively. Differences in response were not significant. The dramatic effect recombinant bovine somatotropin has on production requires that alternative approaches be adopted in the future for accurate genetic evaluation of sires and dams if somatotropin is discriminantly used in the national herd.     

Intermittency phenomena in electrical connectors

Fretting is known to be a major cause of contact deterioration and failure, particularly in tin-plated contacts. During fretting the contact resistance generally increases slowly with time. Superimposed on this slow increase in contact resistance are rapid changes in contact resistance within fractions of a second, called intermittences or short duration discontinuities. Although intermittences have been reported by several authors, they are frequently overlooked in traditional fretting experiments and not much is known about their origin. The present study aims at filling this gap. A test apparatus has been built to measure the contact voltage-drop profile during an intermittence and fretting experiments on tin-plated copper contacts have been carried out. The results lead to a set of requirements for a model to explain intermittency phenomena     

Thermally induced changes in metal solubility of contaminated soils is linked to mineral recrystallization and organic matter transformations

Soils are biogeochemical systems under continual modification by biological and chemical processes. Trace element solid-solution partitioning is thus influenced by long-term changes to these solid phases. We study Pb, Cd, Zn, and Cu solution speciation and solid-phase dynamics in two soils of volcanic origin (Te Akatea and Egmont, high in noncrystalline aluminosilicates), an oxisol from Brazil (Oxisol, high in oxides of Al and Fe), and several sludge-treated soils (labeled NYS soils, high in organic materials). Total soluble (by ICP) and labile (by ASV) concentrations of Pb, Cd, Zn, and Cu were determined after incubation of the soils for about 1.5 yr at room (23 degrees C) and elevated (70 degrees C) temperatures. Changes occurring to the solid phases were monitored by FTIR and extraction with oxalate and pyrophosphate. It is shown that induced hydrolysis or decomposition of organic materials in soils results in increases in both labile and total soluble concentrations of Pb, Cd, Cu, and Zn in solution. Labile and total soluble concentrations of Cu and Zn increase concomitantly with dissolved organic carbon (DOC); the nonlabile soluble fraction also increases with increasing DOC. Similarly, the concentration of Cd and Pb in solution increases with increasing DOC; however, most soluble Cd and Pb is asv-labile. Only in the Egmont soil (mineralogy dominated by proto-imogolite allophane) was reduced Pb solubility observed after prolonged equilibration and heating. Lead solubility increased after partial crystallization of amorphous minerals in the Te Akatea and the Oxisol. Thus, for most of the metal-soil systems studied, prolonged thermal treatment at 70 degrees C increased total soluble and asv-labile metals, suggesting that aging effects on metals in contaminated soils could release metals to labile forms in some cases.     

The cholecystokinin-A receptor mediates inhibition of food intake yet is not essential for the maintenance of body weight

Food intake and body weight are determined by a complex interaction of regulatory pathways. To elucidate the contribution of the endogenous peptide cholecystokinin, mice lacking functional cholecystokinin-A receptors were generated by targeted gene disruption. To explore the role of the cholecystokinin-A receptor in mediating satiety, food intake of cholecystokinin-A receptor-/- mice was compared with the corresponding intakes of wild-type animals and mice lacking the other known cholecystokinin receptor subtype, cholecystokinin-B/gastrin. Intraperitoneal administration of cholecystokinin failed to decrease food intake in mice lacking cholecystokinin-A receptors. In contrast, cholecystokinin diminished food intake by up to 90% in wild-type and cholecystokinin-B/gastrin receptor-/- mice. Together, these findings indicate that cholecystokinin-induced inhibition of food intake is mediated by the cholecystokinin-A receptor. To explore the long-term consequences of either cholecystokinin-A or cholecystokinin-B/gastrin receptor absence, body weight as a function of age was compared between freely fed wild-type and mutant animals. Both cholecystokinin-A and cholecystokinin-B/gastrin receptor-/- mice maintained normal body weight well into adult life. In addition, each of the two receptor-/- strains had normal pancreatic morphology and were normoglycemic. Our results suggest that although cholecystokinin plays a role in the short-term inhibition of food intake, this pathway is not essential for the long-term maintenance of body weight.