基于Copula函数的洪水峰量联合设计方法研究

为明晰洪水峰量联合设计的特点,以岗南水库洪水为例,基于Gumbel Copula函数,分析了AND、OR、Kendall、生存Kendall 4种重现期的优缺点,采用极大似然法、同频率法、条件最可能组合法3种方法计算了联合设计值。结果表明: ①AND和OR重现期在危险域和安全域的识别上存在局限性;相对而言,Kendall重现期更合理,但其安全域是无界的,这与实际不符;生存Kendall重现期则界定了有界的安全域,使得重现期的概念在逻辑上更科学合理。② 3种设计值计算方法的差别不大,但从简单实用角度出发,推荐采用同频率法计算设计值。③不同重现期标准的设计值差别比较明显,基于OR重现期计算的设计值总是最大的,生存Kendall、Kendall重现期设计值次之,AND重现期设计值最小。④推荐采用生存Kendall重现期进行两变量洪水设计,因其有比较严谨的理论基础,且设计结果兼顾了安全性与经济性。⑤两变量联合设计值与单变量设计值的差异受变量间相关性的影响较大,且变量相关性越弱,差异越大。研究显示,基于生存Kendall重现期、采用同频率法计算设计值是目前较为科学合理的洪水峰量联合设计途径。     

基于FPGA的开关量输入模块设计

在测控系统中,经常需要对各种现场信号进行采集;该模块主要实现对开关量状态信号进行实时监控,记录状态信息,为故障诊断提供依据;在设计中,采用了光耦隔离器件对输入信号进行了隔离和抗干扰处理,使用了FPGA实现了数据实时采集和中断处理,最后经PCI总线与主机进行数据交互;在故障诊断系统中,该信号采集板工作稳定、可靠,能够满足系统的实时性要求。     

文科《多媒体技术与应用》课程设置与教学研究

多媒体技术是以数字技术为基础的综合技术。本文结合文科学生的特点,探讨了《多媒体技术与应用》课程设置与教学。     

Mechanical properties of nano SiO2 filled gypsum particleboard

Nano SiO2 was filled into gypsum particleboard. Effect of the amount of nano SiO2 particles filled, ultrasonic dissipating duration and treating the nano particles with different coupling agents on the mechanical properties of the board were studied respectively. The results show that nano SiO2 is helpful for the improvement of the properties. Adding 3%（mass fraction） nano SiO2 is the best for the improvement of both modulus of rupture（MOR） and modulus of elasticity（MOE） of the boards formed at 30 ℃ or 40 ℃. For the boards formed at 30 ℃, their MOR and MOE can be improved by 8.77% and 12.24%, and MOR and MOE of the boards formed at 40 ℃ can be improved by 44.44% and 108.38%.3% is also the best addition proportion to improve internal bond（IB） of the boards formed at 30 ℃, while 5% is the best for that of the boards formed at 40 ℃. At room temperature, dissipating nano Si02 into flake by ultrasonic has better effect on the properties of the final products. Through ultrasonic treating for 1 h and the best treating duration, the MOR and MOE can be increased by 41.99% and 47.80%. In addition, different coupling agents have different effects on the final properties too, and silane coupling agent KH570 is better for the improvement of properties of the boards formed at room temperature.     

Dysregulated CD38 Expression on Peripheral Blood Immune Cell Subsets in SLE

Given its uniformly high expression on plasma cells, CD38 has been considered as a therapeutic target in patients with systemic lupus erythematosus (SLE). Herein, we investigate the distribution of CD38 expression by peripheral blood leukocyte lineages to evaluate the potential therapeutic effect of CD38-targeting antibodies on these immune cell subsets and to delineate the use of CD38 as a biomarker in SLE. We analyzed the expression of CD38 on peripheral blood leukocyte subsets by flow and mass cytometry in two different cohorts, comprising a total of 56 SLE patients. The CD38 expression levels were subsequently correlated across immune cell lineages and subsets, and with clinical and serologic disease parameters of SLE. Compared to healthy controls (HC), CD38 expression levels in SLE were significantly increased on circulating plasmacytoid dendritic cells, CD14⁺⁺CD16⁺ monocytes, CD56⁺ CD16^dim natural killer cells, marginal zone-like IgD⁺CD27⁺ B cells, and on CD4⁺ and CD8⁺ memory T cells. Correlation analyses revealed coordinated CD38 expression between individual innate and memory T cell subsets in SLE but not HC. However, CD38 expression levels were heterogeneous across patients, and no correlation was found between CD38 expression on immune cell subsets and the disease activity index SLEDAI-2K or established serologic and immunological markers of disease activity. In conclusion, we identified widespread changes in CD38 expression on SLE immune cells that highly correlated over different leukocyte subsets within individual patients, but was heterogenous within the population of SLE patients, regardless of disease severity or clinical manifestations. As anti-CD38 treatment is being investigated in SLE, our results may have important implications for the personalized targeting of pathogenic leukocytes by anti-CD38 monoclonal antibodies.     

离子液体/NMP对双马萃余煤的结构和萃取性能影响

为研究离子液体/NMP对双马萃余煤的结构和萃取性能影响,首先分别用乙醇和丙酮对宁东双马煤样(SM)进行分步萃取,得到萃余煤(SMEC),然后将不同种类的离子液体(ILs)分别与N-甲基吡咯烷酮(NMP)混合后对SMEC进行萃取.用TG研究ILs/NMP萃取前后煤样热分解特性的变化,用FT-IR研究ILs/NMP萃取前后煤样官能团的变化,用GC/MS分析萃取物的种类.结果表明,ILs/NMP萃取后煤样的热失重增大,萃余煤中含氧官能团含量下降.另外,疏水型离子液体/NMP对SMEC煤的累积萃取率大于亲水型离子液体/NMP的累积萃取率.亲水型离子液体[Bmim]Cl/NMP和[Bmim]BF4/NMP分别萃取出51种和44种有机物质;疏水型离子液体[Bmim]NTf2/NMP和[Bmim]PF6/NMP分别萃取出28种和29种有机物质.疏水型离子液体/NMP对SMEC煤中含氧官能团化合物的萃取能力强于亲水型离子液体/NMP;疏水型离子液体/NMP对SMEC煤中含杂原子化合物的萃取能力小于亲水型离子液体/NMP.     

热压烧结Ti3AlC2材料的制备、结构与性能研究

采用热压工艺研究了不同工艺制度和原料中不同的Si含量对Ti3AlC2合成的影响.研究表明在1 300℃～1 500℃,30MPa压力和Ar气氛中热压摩尔比为n(TiC)n(Ti)n(Al)n(Si)=2110.2的混合粉末,可以得到纯度达98%(质量分数)以上的致密块体Ti3AlC2材料;添加的Si均匀分布在基体中,形成固溶体,当添加Si的摩尔比为0.2时,固溶体的化学式为Ti2 76Al0 78Si0.22C2.烧结试样的晶体为层片状结构,1 300℃和1 400℃时,烧结试样的晶粒尺寸分别为10μm～15μm和20μm～30μm.材料的维氏硬度为3.3 GPa～5.0 GPa,弹性模量为289 GPa,抗压强度为785 MPa,抗弯强度为375 MPa,断裂韧性为7.0 MPa·m1/2;25℃时,电导率为3.1×106 S·m-1,热容为125.4 J/mol·K,热导率为27.5 W/m·K;热膨胀系数为8.8×10-6 K-1.     

含硼金刚石的金属包膜成分及其物相的研究

本文采用铁基触媒加入硼铁的方法，在高温高压条件下合成了含硼金刚石，利用电子探针（EPMA），透射电子显微镜（TEM）两种检测手段，分析了含硼金刚石金属包膜的微观组织结构，化学组成成分，各组成成分的物相及其可能形成的原因。研究结果表明：金属包膜的成分及其物相由正交立方结构的（Fe,Ni）3C，面心立方的γ-（Fe,Ni），面心立方的Fe23（C，B）。及少量的FeB,Ni3B组成，这些成份主要来源于原材料，其含量在高温压过程中是瞬间变化的。     

Microstructure of Titanium after Hydrogenation

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工作流技术在ASP公共服务平台中的应用研究*

根据项目特点,建立了适合ASP平台的基于协调理论和反馈机制的扩展活动网络模型,采用XML模式的XPDL规范实现过程定义;然后通过DOM解析XML数据文档和J2EE的技术支持实现了系统的轻量级工作流引擎.详细介绍了系统实现中解决的两个关键问题:事务型操作的处理和并发控制,并提出了基于优先级的锁绑定机制.