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61.
F Würschmidt H Bünemann C Bünemann HP Beck-Bornholdt HP Heilmann 《Canadian Metallurgical Quarterly》1994,170(5):302-304
BACKGROUND: The influence of tumor and patient characteristics on survival as well as acute normal tissue toxicity was retrospectively analyzed. PATIENTS AND METHODS: 427 patients with inoperable non-small cell lung cancer were retrospectively analyzed. Two thirds received a total dose of at least 70 Gy, and one third was irradiated with 60 to 66 Gy (2.0 to 2.5 Gy per fraction; split-course technique). 92% had a Karnofsky performance index of > or = 80%. Kaplan-Meier survival curves were generated and comparisons were made by the log-rank test. Prognostic factors were adjusted for by a proportional hazards analysis. RESULTS: Five-year survival rates (+/- SE) and the median survival times (95% confidence interval) were 2 +/- 2% and 11.1 months (9.1 ... 14.5) after 60 to 66 Gy; 8 +/- 2% and 14.9 months (13.3 ... 16.5) after 70+ Gy. The difference was significant in univariate (p = 0.0013) and multivariate analysis (p = 0.0006). Tumor stage (p = 0.0029: I + II > III; IIIA > IIIB) and gender (p = 0.0387: female > male patients) reached significance in multivariate analysis. Acute pneumonitis and esophagitis were observed in 11% and 9% of cases. CONCLUSIONS: Inoperable non-small cell lung cancer stage I to IIIA should be treated in a curative intention with total doses of about 70 Gy. This is feasible with acceptable normal tissue toxicity. Stage IIIB patients have a particular bad prognosis and should only be treated palliatively. 相似文献
62.
HP Raghuveer 《Canadian Metallurgical Quarterly》1994,8(3):107-109
A case of Solitary Central Neurofibroma in a 53 years old female is reported. This is an apparently single primary lesion, in which physical and Radiological examination failed to reveal other bony lesions or the stigmata of multiple neurofribomatosis. 相似文献
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With the aid of a double-tilt holder in a transmission electron microscope, a new method for a rapid and precise determination of the misorientations of a large number of subgrain or grain boundaries is given in this article. By use of the method, the continuous recrystallization can be rapidly and precisely evaluated when compared to the other conventional methods. 相似文献
65.
It is shown that a superconductor cannot be simply treated as a low-loss conductor; rather, it should be treated as a negative dielectric material (with a negative dielectric constant). This approach is good only for vanishingly small field application with frequency significantly smaller than gap frequency and temperature not too close to the critical temperature of the superconductor. The electromagnetics of negative dielectric materials are discussed in terms of causality, perturbation technique, surface impedance, time-domain interpretation of current components, and computational electrodynamics 相似文献
66.
A modification to the time-domain finite-difference method (TDFDM) that uses a variable step size is investigated. The entire computational volume is divided into a coarse grid with a large step size. A fine grid with a small step size is introduced only around discontinuities. The corresponding time increments are related to the spatial increments with the same ratio in order to minimize the numerical dispersion. The fields within the coarse and fine grids are found using the TDFDM, while an interpolation in space and time is utilized to calculate the tangential electric field on the coarse-fine grid boundary. This subgridding decreases the required computer memory and therefore expands the capability of the TDFDM. The technique is shown to be numerically stable and does not entail any extra numerical error. The method is applied to the calculation of waveguides and microstrips 相似文献
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