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排序方式: 共有521条查询结果,搜索用时 817 毫秒
481.
建立加速度计静态模型方程并根据工程应用对方程进行简化,针对加速度计静态模型的参数辨识提出一种新的方法--数据融合,使模型参数的精度有明显的提高.该方法的提出为控制系统的实时补偿提供了更好的条件. 相似文献
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The objective of this research was to develop novel polymer coated magnetic nanoparticles for controlled drug delivery applications. To form these novel nanoparticles, silane-coated magnetic nanoparticles (MNPs) were used as a template for a free radial polymerization of three monomers, N-isopropylacrylamide, acrylamide, and allylamine (NIPA-AAm-AH), on the surface of MNPs. Transmission electron microscope results indicated that the size of the NIPA-AAm-AH coated MNPs was approximately 100 nm. To investigate the chemical composition and chemical state of our nanoparticles, FTIR and XPS were used. Results from chemical analysis illustrated the presence of the constituent functional groups of the NIPA-AAm-AH coated MNPs. In addition, the magnetic properties of different layers on the MNPs, analyzed by SQUID, indicated a decrease in saturation magnetization after each layer of coating. The nanoparticles were successfully conjugated to fluorescent PEG to prolong their circulating half life. Furthermore, bovine serum albumin (BSA) was used in order to investigate the protein release profile of the nanoparticles as a function of the temperature. The protein release profile indicated that the NIPA-AAm-AH coated MNPs have a significantly higher percent release at 41 degrees C compared to those of 4 degrees C and 37 degrees C, which demonstrates their temperature sensitivity. In the future, the release profile of therapeutic drugs from nanoparticles at various temperatures and pHs as well as targeted capability of the synthesized nanoparticles for possible applications in controlled and targeted delivery will be investigated. 相似文献
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485.
喷气涡流纺喷嘴内气流流动的二维数值模拟 总被引:3,自引:1,他引:2
为探讨喷嘴内部气流流动特征对纤维加捻成纱的作用,建立计算流体动力学(CFD)模型,对喷气涡流纺喷嘴中的气流流动进行二维数值模拟,并根据计算结果分析喷嘴内高速气流的速度场和压力场分布。模拟结果表明:气流的最大速度可达超音速,由于切向速度所产生的离心力和加捻作用,纤维的尾端从纤维束中分离出来,并旋转加捻到纤维束上,形成具有真捻的纱线;喷嘴入口区域的压力小于外界气压,这有利于由前罗拉钳口处输出的纤维束吸入喷嘴。研究还表明CFD技术是研究喷气涡流纺喷嘴内气流流动的重要手段。 相似文献
486.
Jia Haiqiang Wang Changhe Li Xiaobai The th Institute Ministry of EI Shijiazhuang ) 《微纳电子技术》1994,(4)
描述了高电子迁移率晶体管的作用、工作原理及发展概况,叙述了器件特性。制作出了栅长为1μm的PHEMT样品,它的最大跨导为170mS/mm,击穿电压为4V,最大电流密度为270mA/mm,阈值电压为1.5V。 相似文献
487.
Increasing plasma free fatty acids decreased the degree of glycogen depletion, and increased the citrate concentration, in slow-red (soleus) and fast-red (deep portion of vastus lateralis) muscle during exercise (approx. 50% depletion of glycogen, as against 75% in control animals). There was no effect in fast-white muscle (superficial portion of vastus lateralis). Glycogen concentration in the liver decreased by 83% in controls, but only by 23% in animals with increased free fatty acids during exercise. The decreased glycogen depletion may be partly explained by the findings that (a) plasma-insulin concentration was two- to three-fold higher in animals with increased plasma free fatty acids and (b) the exercise-induced increase in plasma glucagon was lessened by increased free fatty acids. Blood glucose was higher in the animals with increased free fatty acids after the exercise. The rats with increased plasma free fatty acids utilized approx. 50% as much carbohydrate as did the controls during the exercise. 相似文献
488.
SM Prasad Y Yin E Rodzinski EI Tuomanen HR Masure 《Canadian Metallurgical Quarterly》1993,61(7):2780-2785
The adherence of Bordetella pertussis to ciliated cells and macrophages is critical to colonization and infection of the respiratory tract. Adherence to both types of cells involves the recognition of eukaryotic carbohydrates by the bacterial adhesin filamentous hemagglutinin (Fha). The carbohydrate recognition domain (CRD) of Fha is considered an important antigen for subcomponent vaccines to maximize the generation of antiadherence antibodies capable of protecting against colonization. For identification of the CRD of Fha, a bank of eight monoclonal antibodies (MAbs) that mapped to four contiguous regions were tested for their ability to block Fha binding to lactosylceramide or to block bacterial binding to ciliated cells. Only MAb 12.5A9, which maps to amino acid residues 1141 to 1279, blocked both Fha binding to lactosylceramide and bacterial binding to ciliated cells. An 18-kDa polypeptide corresponding to this region was expressed in Escherichia coli. Cell lysates containing this protein bound to lactosylceramide in a manner identical to that of native Fha. Mutant strains of B. pertussis that contained an in-frame deletion of the coding sequence for this region produced a truncated Fha that showed negligible cross-reactivity with MAb 12.5A9. In an adherence assay, these mutant strains failed to bind efficiently to either ciliated cells or macrophages. The numbers of adherent bacteria for these strains were reduced to the number obtained with a nonadherent strain. We conclude that the region defined by residues 1141 to 1279 of Fha constitutes a CRD critical for bacterial adherence and represents a potential candidate for a subcomponent vaccine. 相似文献
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490.