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排序方式: 共有668条查询结果,搜索用时 15 毫秒
41.
C Eder P Proksch V Wray K Steube G Bringmann RW van Soest Sudarsono E Ferdinandus LA Pattisina S Wiryowidagdo W Moka 《Canadian Metallurgical Quarterly》1999,62(1):184-187
Two samples of the marine sponge Stylissa carteri collected in Indonesia yielded two new bromopyrrole alkaloids: debromostevensine (1) and debromohymenin (2), as well as nine other known congeners (3-11). The structures of the new compounds were unambiguously established on the basis of their NMR and mass spectra. 相似文献
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Kiernan Michaela; Kraemer Helena C.; Winkleby Marilyn A.; King Abby C.; Taylor C. Barr 《Canadian Metallurgical Quarterly》2001,6(1):35
Identifying subgroups of high-risk individuals can lead to the development of tailored interventions for those subgroups. This study compared two multivariate statistical methods (logistic regression and signal detection) and evaluated their ability to identify subgroups at risk. The methods identified similar risk predictors and had similar predictive accuracy in exploratory and validation samples. However, the 2 methods did not classify individuals into the same subgroups. Within subgroups, logistic regression identified individuals that were homogeneous in outcome but heterogeneous in risk predictors. In contrast, signal detection identified individuals that were homogeneous in both outcome and risk predictors. Because of the ability to identify homogeneous subgroups, signal detection may be more useful than logistic regression for designing distinct tailored interventions for subgroups of high-risk individuals. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
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The advantages of mathematical simulations of the process of cured hide desalination are presented. Full three‐dimensional model is presented and then its one‐dimensional and a two‐dimensional special cases are considered and compared. In the case of one‐dimensional approximation, the solution can be obtained in an analytic form, while for the two‐dimensional case only numerical solution is available. A possible occurrence of a concentration shock is modelled, and a method of its prevention is proposed to reduce losses in the hide substance. The predictions of the mathematical model are then compared with experimental data and found to be in good agreement. 相似文献
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Tomas Selicky Matus Jurcik Barbora Mikolaskova Alexandra Pitelova Nina Mayerova Miroslava Kretova Michaela Osadska Jan Jurcik Roman Holic Lenka Kohutova Jana Bellova Zsigmond Benko Juraj Gregan Silvia Bagelova Polakova Peter Barath Lubos Cipak Ingrid Cipakova 《International journal of molecular sciences》2022,23(21)
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Nadine de Godoy Torso Marília Berlofa Visacri Julia Coelho Frana Quintanilha Maria Aparecida Cursino Eder de Carvalho Pincinato Patricia Moriel 《International journal of molecular sciences》2023,24(1)
Cisplatin is associated with dose-limiting nephrotoxicity, and the timely detection of acute kidney injury (AKI) can affect morbimortality. Therefore, this study aimed to investigate the tools for monitoring renal function in AKI. This was a retrospective, cohort study. Cisplatin-treated patients with head and neck cancer were included. Nephrotoxicity was assessed using serum creatinine, estimated creatinine clearance, serum electrolytic alterations, and plasma kidney injury molecule-1 (KIM-1). The toxicity severity was classified according to Common Terminology Criteria for Adverse Events (CTCAE), and AKI was classified by Risk, Injury, Failure, Loss, and End-stage kidney disease (RIFLE) and Acute Kidney Injury Network (AKIN). A total of 81 participants were included, of whom only 32 did not have AKI. Almost 90% of participants had a decreased estimated glomerular filtration rate five (D5) days after chemotherapy. The AKI estimate differs between AKIN and RIFLE; more participants were diagnosed by the RIFLE at D5, 19.5% versus 2.4% by AKIN, and fifteen had a discordance between these classifications. All laboratory markers showed significant changes on D5. KIM-1 appeared a possible biomarker when considering CTCAE or AKIN classifications (p < 0.05 on D5), but not when RIFLE classification was used (p = 0.0780). Further studies may seek to understand the profiles of different biomarkers together. 相似文献