Disinfection of surgical silk with decamethoxin, antibiotics and their combinations

The disinfecting effect of decametoxin, antibiotics, such as bensylpenicillin, streptomycin, monomycin and their combinations was studied on surgical threads of various thickness previously infected with Staph. aureus, Pr. vulgaris, Bac. anthracis, E. coli, Ps. aeruginosa and Bac. subtilis. It was shown that disinfection of the surgical silk with 0.1% solution of decametoxin for 15 minutes followed by its treatment with an antibiotic solution for 105 minutes provided absolute sterility. Treatment of the surgical silk with decametoxin and antibiotic combinations alone did not provide absolute destruction of the above test-microbes. It was found that treatment of the silk with 0.1% decametoxin solution for 24 hours did not decrease its strength.     

Effects of pinealectomy of rams on secretory profiles of luteinizing hormone, testosterone, prolactin and cortisol

In a study of pineal gland influences on hormone secretory profiles, blood samples were collected at 20 min intervals for 26 h from 4 pinealectomized and 4 sham-operated rams which were subjected to a 14.5 h daily photoperiod. Plasma levels of luteinizing hormone (LH) and testosterone (T) underwent rapid pulsatile fluctuations in all rams. Pinealectomized rams produced more LH than the sham-operated rams and a similar trend was recorded for plasma T data, since T secretion closely followed that of LH. A nocturnal elevation of plasma prolactin (Prl) levels displayed by sham-operated rams was substantially abolished by pinealectomy. Also a rise in cortisol secretion during the morning hours recorded from 3 of the sham-operated rams was absent in 2 of the pinealectomized rams. The possible significance of the pineal gland in the regulation of secretion of these hormones is discussed.