This study has been undertaken to develop a controlled-release tablet dosage form of naproxen using ethocel (ethyl cellulose) as the rate-controlling polymer. The formulations were made by employing the conventional wet-granulation method and the solid-dispersion method. Tablets made by both methods were compared for their controlled-release dissolution profiles. Both methods were useful in developing the controlled-release formulations of naproxen with desirable properties. However, the amount of polymer required to make a formulation with the desired release profile was 33% less via solid dispersion than via wet granulation. A cumulative 88% of naproxen was released from the solid-dispersion formulation, compared with 84% from the wet-granulation formulation. 相似文献
This paper reports an enhancement of the electrical properties of micro-silicon carbide/silicone elastomer (m-SiC/SE) composites by adding nano-aluminum nitride (n-AlN) for the next-generation power module encapsulation applications. The electrical properties, such as nonlinear conductivity, DC breakdown strength, dielectric spectroscopy, and thermally stimulated discharge current, of the pure SE, m-SiC/SE microcomposite, and m-SiC/n-AlN/SE hybrid composites added with 1 wt%, 3 wt%, and 5 wt% n-AlN fillers are investigated. The m-SiC/n-AlN/SE hybrid composites exhibit better nonlinear conductivity characteristics and enhanced DC breakdown strength than the m-SiC/SE microcomposite. Amongst all materials, the 3 wt% n-AlN addition in the hybrid composite has the best enhancement effect on the nonlinear conductivity characteristics and DC breakdown strength. However, it has the lowest low-frequency real and imaginary permittivities among the SE micro and hybrid composites. Furthermore, a m-SiC/n-AlN heterogenous interface model is proposed to explain the mechanism of enhanced electrical properties of the m-SiC/n-AlN/SE composites. It is found that higher m-SiC/n-AlN heterogenous interface barriers are constructed after adding n-AlN fillers, thereby inhibiting the charge carrier transport at low electric fields. In contrast, more conductive paths are activated at high electric fields by the contacted m-SiC fillers via n-AlN fillers, promoting the charge carrier transport at high electric fields.
In recent years, the number of Gun-related incidents has crossed over 250,000 per year and over 85% of the existing 1 billion firearms are in civilian hands, manual monitoring has not proven effective in detecting firearms. which is why an automated weapon detection system is needed. Various automated convolutional neural networks (CNN) weapon detection systems have been proposed in the past to generate good results. However, These techniques have high computation overhead and are slow to provide real-time detection which is essential for the weapon detection system. These models have a high rate of false negatives because they often fail to detect the guns due to the low quality and visibility issues of surveillance videos. This research work aims to minimize the rate of false negatives and false positives in weapon detection while keeping the speed of detection as a key parameter. The proposed framework is based on You Only Look Once (YOLO) and Area of Interest (AOI). Initially, the models take pre-processed frames where the background is removed by the use of the Gaussian blur algorithm. The proposed architecture will be assessed through various performance parameters such as False Negative, False Positive, precision, recall rate, and F1 score. The results of this research work make it clear that due to YOLO-v5s high recall rate and speed of detection are achieved. Speed reached 0.010 s per frame compared to the 0.17 s of the Faster R-CNN. It is promising to be used in the field of security and weapon detection. 相似文献
To determine the individual circumstances that account for a road traffic accident, it is crucial to consider the unplanned connections amongst various factors related to a crash that results in high casualty levels. Analysis of the road accident data concentrated mainly on categorizing accidents into different types using individually built classification methods which limit the prediction accuracy and fitness of the model. In this article, we proposed a multi-model hybrid framework of the weighted majority voting (WMV) scheme with parallel structure, which is designed by integrating individually implemented multinomial logistic regression (MLR) and multilayer perceptron (MLP) classifiers using three different accident datasets i.e., IRTAD, NCDB, and FARS. The proposed WMV hybrid scheme overtook individual classifiers in terms of modern evaluation measures like ROC, RMSE, Kappa rate, classification accuracy, and performs better than state-of-the-art approaches for the prediction of casualty severity level. Moreover, the proposed WMV hybrid scheme adds up to accident severity analysis through knowledge representation by revealing the role of different accident-related factors which expand the risk of casualty in a road crash. Critical aspects related to casualty severity recognized by the proposed WMV hybrid approach can surely support the traffic enforcement agencies to develop better road safety plans and ultimately save lives. 相似文献
The use of multimedia data sharing has drastically increased in the past few decades due to the revolutionary improvements in communication technologies such as the 4th generation (4G) and 5th generation (5G) etc. Researchers have proposed many image encryption algorithms based on the classical random walk and chaos theory for sharing an image in a secure way. Instead of the classical random walk, this paper proposes the quantum walk to achieve high image security. Classical random walk exhibits randomness due to the stochastic transitions between states, on the other hand, the quantum walk is more random and achieve randomness due to the superposition, and the interference of the wave functions. The proposed image encryption scheme is evaluated using extensive security metrics such as correlation coefficient, entropy, histogram, time complexity, number of pixels change rate and unified average intensity etc. All experimental results validate the proposed scheme, and it is concluded that the proposed scheme is highly secured, lightweight and computationally efficient. In the proposed scheme, the values of the correlation coefficient, entropy, mean square error (MSE), number of pixels change rate (NPCR), unified average change intensity (UACI) and contrast are 0.0069, 7.9970, 40.39, 99.60%, 33.47 and 10.4542 respectively. 相似文献
Here in, we report the charge transport mechanism in semiconducting La0.5Ca0.5Mn0.5Fe0.5O3 (LCMFO) polycrystalline material synthesized via sol–gel auto combustion route. X-ray diffraction (XRD) analysis confirmed the orthorhombic phase of the prepared material. Temperature dependent resistivity and impedance spectroscopy measurements have been carried out to probe the dielectric and electrical conduction mechanism which revealed a change of Mott variable range to the small polaronic hopping conduction mechanism around 303 K. The complex impedance and modulus spectra undoubtedly showed the contribution of both grain and grain boundary effect on the conduction properties of LCMFO. An equivalent circuit [(RgbQgb) (RgQg)] model has been used to address the electrical parameters associated with the different phases (grains and grain boundaries) having different relaxation times. The values of resistances of two phases obtained after fitting the equivalent circuit in the nyquist plot have been analyzed which confirmed the change of conduction mechanism around 303 K. The resultant change in conduction mechanism is also supported by the conductivity plots. 相似文献
Microbial fuel cells (MFCs) are an environmentally friendly method for water purification and self-sustained electricity generation using microorganisms. Microsized MFCs can also be a useful power source for lab-on-a-chip and similar integrated devices. We fabricated a 1.25 μL microsized MFC containing an anode of vertically aligned, forest type multiwalled carbon nanotubes (MWCNTs) with a nickel silicide (NiSi) contact area that produced 197 mA/m(2) of current density and 392 mW/m(3) of power density. The MWCNTs increased the anode surface-to-volume ratio, which improved the ability of the microorganisms to couple and transfer electrons to the anode. The use of nickel silicide also helped to boost the output current by providing a low resistance contact area to more efficiently shuttle electrons from the anode out of the device. 相似文献