SIMS and RBS analysis of leached glass: Reliability of RSF method for SIMS quantification

The reliability of the relative sensitivity factor (RSF) approach for secondary ion mass spectrometry (SIMS) quantification of the leached layers on glass was investigated by measuring comparable samples of glass with SIMS and RBS (Rutherford backscattering spectrometry). The RSF factors were calculated using the nominal bulk compositions. Accurate results can be obtained only when the leached layer and the bulk glass have the same major elemental compositions (Si and O) and the matrix effect is inhibited. The concentrations of the different elements in the leached layer obtained from the comparable samples measured by SIMS and RBS are coincident within a factor of 2This paper is a part of a thesis submitted in partial fulfilment of the requirements for the PhD degree at the University of Technology of Vienna, 1991. The paper was orally presented in a symposium, Analysis of Working Materials, held in Vienna, 22–29 May 1991.     

Hybrid intelligent techniques for MRI brain images classification

This paper presents a hybrid technique for the classification of the magnetic resonance images (MRI). The proposed hybrid technique consists of three stages, namely, feature extraction, dimensionality reduction, and classification. In the first stage, we have obtained the features related to MRI images using discrete wavelet transformation (DWT). In the second stage, the features of magnetic resonance images have been reduced, using principal component analysis (PCA), to the more essential features. In the classification stage, two classifiers have been developed. The first classifier based on feed forward back-propagation artificial neural network (FP-ANN) and the second classifier is based on k-nearest neighbor (k-NN). The classifiers have been used to classify subjects as normal or abnormal MRI human images. A classification with a success of 97% and 98% has been obtained by FP-ANN and k-NN, respectively. This result shows that the proposed technique is robust and effective compared with other recent work.     

SimClus: an effective algorithm for clustering with a lower bound on similarity

Clustering algorithms generally accept a parameter k from the user, which determines the number of clusters sought. However, in many application domains, like document categorization, social network clustering, and frequent pattern summarization, the proper value of k is difficult to guess. An alternative clustering formulation that does not require k is to impose a lower bound on the similarity between an object and its corresponding cluster representative. Such a formulation chooses exactly one representative for every cluster and minimizes the representative count. It has many additional benefits. For instance, it supports overlapping clusters in a natural way. Moreover, for every cluster, it selects a representative object, which can be effectively used in summarization or semi-supervised classification task. In this work, we propose an algorithm, SimClus, for clustering with lower bound on similarity. It achieves a O(log n) approximation bound on the number of clusters, whereas for the best previous algorithm the bound can be as poor as O(n). Experiments on real and synthetic data sets show that our algorithm produces more than 40% fewer representative objects, yet offers the same or better clustering quality. We also propose a dynamic variant of the algorithm, which can be effectively used in an on-line setting.     

The concept of work compatibility: An integrated design criterion for improving workplace human performance in manufacturing systems

In this paper, we present the concept of work compatibility as an integrated work design criterion that simultaneously improves human health and safety, productivity, and work quality in manufacturing systems. In this respect, we have modeled work compatibility as a work design parameter that mathematically integrates the energizing (i.e., system resources) and the demand (i.e., system requirements) forces in the work system. A mathematical equation has been derived for the work compatibility matrix. Furthermore, an operating zone has been developed in which there is a region of optimality for the employee to function on practical grounds with a good degree of efficiency and sustainability. An application example is provided to demonstrate the potential of work compatibility to improve productivity and quality along with improvement in worker safety and health. © 2004 Wiley Periodicals, Inc. Hum Factors Man 14: 379–402, 2004.     

MicroRNA Expression in Clear Cell Renal Cell Carcinoma Cell Lines and Tumor Biopsies: Potential Therapeutic Targets

This study was carried out to quantitate the expression levels of microRNA-17, -19a, -34a, -155, and -210 (miRs) expressed in nine clear cell renal cell carcinoma (ccRCC) and one chromophobe renal cell carcinoma cell line with and without sarcomatoid differentiation, and in six primary kidney tumors with matching normal kidney tissues. The data in the five non-sarcomatoid ccRCC cell lines—RC2, CAKI-1, 786-0, RCC4, and RCC4/VHL—and in the four ccRCC with sarcomatoid differentiation—RCJ41T1, RCJ41T2, RCJ41M, and UOK-127—indicated that miR-17 and -19a were expressed at lower levels relative to miR-34a, -155, and -210. Compared with RPTEC normal epithelial cells, miR-34a, miR-155, and miR-210 were expressed at higher levels, independent of the sarcomatoid differentiation status and hypoxia-inducible factors 1α and 2α (HIFs) isoform expression. In the one chromophobe renal cell carcinoma cell line, namely, UOK-276 with sarcomatoid differentiation, and expressing tumor suppressor gene TP53, miR-34a, which is a tumor suppressor gene, was expressed at higher levels than miR-210, -155, -17, and -19a. The pilot results generated in six tumor biopsies with matching normal kidney tissues indicated that while the expression of miR-17 and -19a were similar to the normal tissue expression profile, miR-210, -155, -and 34a were expressed at a higher level. To confirm that differences in the expression levels of the five miRs in the six tumor biopsies were statistically significant, the acquisition of a larger sample size is required. Data previously generated in ccRCC cell lines demonstrating that miR-210, miR-155, and HIFs are druggable targets using a defined dose and schedule of selenium-containing molecules support the concept that simultaneous and concurrent downregulation of miR-210, miR-155, and HIFs, which regulate target genes associated with increased tumor angiogenesis and drug resistance, may offer the potential for the development of a novel mechanism-based strategy for the treatment of patients with advanced ccRCC.     

Fabrication of High Performance PM Nanocrystalline Bulk AA2124

AA2124 nanopowders <100 nm in particle size and 20 nm internal structure produced by high energy ball milling of gas-atomized micronpowders ~45 μm in particle size and 700 nm internal structure were processed in to bulk rods. The micro- and nanopowders were hot compacted using uniaxial pressing for preliminary densification at 0.7T _m of the alloy. Selected intact hot compacts (HCs) were promoted for warm severe plastic deformation via equal channel angular pressing (ECAP) at the minimum possible deforming temperature for final densification. Effect of the fabrication method of the consolidated powders was investigated. A combined processing via HC/ECAP produced bulk nanostructured rods 2.5 μm and 50-60 nm in grain size for the micro- and nanopowder consolidates, respectively. The powder properties controlled the degree of densification and mechanical behavior during the hot compaction stage, which influenced strongly the deformation behavior during subsequent ECAP. At the end of HC/ECAP one pass, the HC stage was responsible for about 83 and 95% of the total grain coarsening encountered for the micro- and nanopowder HCs, respectively. Throughout the various consolidation stages employed, the ball-milled (BM) nanopowder consolidates exhibited 2/3 the grain growth and displayed almost twice the hardness and compressive strength values of the gas-atomized micronpowder ones. Influence of BM and HC on the Al₂O₃ layer formed around the individual powder particles was also investigated.     

Evaluating thermal and thermooxidation stability for lubricating oils via microscale methods

Differential thermal analysis (DTA) and thermogravimetry (TG) methods have been developed to evaluate the thermal and thermooxidation stability of different lubricating oils. Measurements are carried out either by heating the oil sample at a constant rate (direct programme) or by keeping it at a fixed high temperature (isothermal programme). Oxygen at a constant flow rate is used for thermooxidation measurements. Tested samples included different viscosity grades: neutral base oils, unadditivated lubricating oil blends, and industrial oils. The mechanism of thermal decomposition for ZDDP and the estimation of its optimum concentration was also considered.     

Effect of Ni Addition on the Morphology and Microstructure of Both Conventional Cast and Melt-Spun of Al–Si–Fe–Nb (at wt%) Alloy

Metals and Materials International - In this project the morphology and microstructure of both conventional cast and melt spun of Al–20Si–9Fe–1.2Nb and...     

Lean Construction: From Theory to Implementation

This article compares the techniques developed for lean construction with those developed for lean manufacturing. Lean manufacturing and lean construction techniques share many common elements despite the obvious differences in their assembly environments and processes. Manufacturing plants and construction sites are different in many ways that might explain why lean production theories and practices do not fully fit the construction industry. Though many lean construction tools and elements are still in an embryonic state, lean construction techniques are gaining popularity because they can affect the bottom line of projects. Additionally, this paper presents a study of a construction project in which specific lean construction elements were tested. Each technique was evaluated in terms of its impact on the performance of the project. Based on the findings of the study, a new “lean assessment tool” is proposed to quantify the results of lean implementations. The assessment tool evaluates six lean construction elements: last planner, increased visualization, huddle meetings, first-run studies, five S’s, and fail safe for quality. This paper provides a simple and comprehensive approach that is transferable to any construction project.