A robust feature extraction with optimized DBN-SMO for facial expression recognition

Multimedia Tools and Applications - Facial expression is the most common technique is used to convey the expressions of human beings. Due to different ethnicity and age, faces differ from one...     

Effect of Long-Term Thermal Exposures on Microstructure and Impression Creep in 304HCu Grade Austenitic Stainless Steel

Metallurgical and Materials Transactions A - This paper presents the results of microstructural evolution and mechanical properties in 304H Cu grade austenite stainless (SS 304HCu) during long-term...     

A simple demonstration of the Pancharatnam phase as a geometric phase

Abstract

To demonstrate the Pancharatnam phase as a geometric (Berry's) phase, each polarization state must be obtained by projecting the previous state on it. We describe a simple interferometric arrangement for such a demonstration which only uses a single rotation linear analyser to introduce a continuously variable phase difference between the two beams.     

Lanthanide Doped Near Infrared Active Upconversion Nanophosphors: Fundamental Concepts,Synthesis Strategies,and Technological Applications

Near infrared (NIR) light utilization in a range of current technologies has gained huge significance due to its abundance in nature and nondestructive properties. NIR active lanthanide (Ln) doped upconversion nanomaterials synthesized in controlled shape, size, and surface functionality can be combined with various pertinent materials for extensive applications in diverse fields. Upconversion nanophosphors (UCNP) possess unique abilities, such as deep tissue penetration, enhanced photostability, low toxicity, sharp emission peaks, long anti‐Stokes shift, etc., which have bestowed them with prodigious advantages over other conventional luminescent materials. As new generation fluorophores, UCNP have found a wide range of applications in various fields. In this Review, a comprehensive overview of lanthanide doped NIR active UCNP is provided by discussing the fundamental concepts including the different mechanisms proposed for explaining the upconversion processes, followed by the different strategies employed for the synthesis of these materials, and finally the technological applications of UCNP, mainly in the fields of bioimaging, drug delivery, sensing, and photocatalysis by highlighting the recent works in these areas. In addition, a brief note on the applications of UCNP in other fields is also provided along with the summary and future perspectives of these materials.     

Evaluation of potential anti‐cancer activity of cationic liposomal nanoformulated Lycopodium clavatum in colon cancer cells

Research dealing with early diagnosis and efficient treatment in colon cancer to improve patient''s survival is still under investigation. Chemotherapeutic agent result in high systemic toxicity due to their non‐specific actions on DNA repair and/or cell replication. Traditional medicine such as Lycopodium clavatum (LC) has been claimed to have therapeutic potentials against cancer. The present study focuses on targeted drug delivery of cationic liposomal nanoformulated LC (CL‐LC) in colon cancer cells (HCT15) and comparing the efficacy with an anti‐colon cancer drug, 7‐ethyl‐10‐hydroxy‐camptothecin (SN38) along with its nanoformulated form (CL‐SN38). The colloidal suspension of LC was made using thin film hydration method. The drugs were characterised using ultraviolet, dynamic light scattering, scanning electron microscopy, energy, dispersive X‐ray spectroscopy. In vitro drug release showed kinetics of 49 and 89% of SN38 and LC, whereas CL‐SN38 and CL‐LC showed 73 and 74% of sustained drug release, respectively. Studies on morphological changes, cell viability, cytotoxicity, apoptosis, cancer‐associated gene expression analysis of Bcl‐2, Bax, p53 by real‐time polymerase chain reaction and western blot analysis of Bad and p53 protein were performed. Nanoformulated LC significantly inhibited growth and increased the apoptosis of colon cancer cells indicating its potential anti‐cancer activity against colon cancer cells.Inspec keywords: cancer, biological organs, cellular biophysics, drug delivery systems, drugs, nanomedicine, genetics, DNA, molecular biophysics, biochemistry, lipid bilayers, toxicology, suspensions, colloids, light scattering, X‐ray chemical analysis, solvation, enzymes, nanostructured materialsOther keywords: energy dispersive X‐ray spectroscopy, in vitro drug release, morphological changes, cell viability, cytotoxicity, apoptosis, cancer‐associated gene expression analysis, Bcl‐2, Bax, real‐time polymerase chain reaction, western blot analysis, Bad protein, p53 protein, scanning electron microscopy, dynamic light scattering, ultraviolet scattering, thin film hydration method, colloidal suspension, nanoformulated form CL‐SN38, 7‐ethyl‐10‐hydroxy‐camptothecin, anticolon cancer drug, colon cancer cells HCT15, cationic liposomal nanoformulated LC, targeted drug delivery, therapeutic potentials, Lycopodium clavatum, traditional medicines, cell replication, DNA repair, nonspecific actions, high systemic toxicity, chemotherapeutic agents, patient survival, colon cancer treatment, colon cancer diagnosis, CL‐LC, potential anticancer activity     

The iterative contribution and relevance of modelling to UK energy policy

This paper discusses the iterative provision of modelling insights on long-term decarbonisation scenarios for UK energy policy makers. A multi-year model construction process of the UK MARKAL-Macro-hybrid energy-economic model, and four subsequent major policy analyses illustrates the scope of this interaction. The initial set of modelling runs focused on the technical feasibility of long-term 60% carbon dioxide (CO₂) reduction scenarios, the role of key technologies, and the underlying uncertainties. Furthermore subsequent modelling studies were aimed to generate insights on more stringent targets, and on issues and uncertainties that may make targets harder to achieve. Hence, this paper analyses the large number of long-term UK CO₂ reduction scenarios through a clustering approach on target stringency and barriers to implementation. Robust findings and key uncertainties are highlighted, including the critical role of the power sector, trade-offs between resources, sectors, key energy technologies and behavioural responses, and the increasing level and spread of CO₂ marginal prices and GDP impacts. The relevance and use of modelling insights to the UK energy policy process is shown in the continuation of the energy modelling–policy interface. This constitutes both ongoing model development, and nuanced scenario analysis designed to further explore key uncertainties in evolving policy issues.     

Modularization of a Large-Scale Business Application: A Case Study

Large software systems, developed over several years, are the backbone of industries such as banking, retail, transportation, and telecommunications. With multiple bug fixes and feature enhancements, these systems gradually deviate from the intended architecture and deteriorate into unmanageable monoliths. This article presents a case study of a banking application besot with such problems and the modularization approach that the company adopted as a solution. It also highlights benefits unearthed as a result of this reengineering exercise.     

Lattice dynamics of colloidal crystals during photopolymerization of acrylic monomer matrix

The photoinitiated bulk polymerization process, which has been used recently in the manufacture of solid optical diffraction filters, is examined to understand the dynamics of both the crystalline colloidal arrays (CCA) and the host monomer species. Our analysis indicates that volume shrinkage of the monomer, changes in the dielectric properties of the monomer, and inhomogeneities of polymerization reaction rate across the dispersion during the polymerization process, are the major contributors for observed lattice compression and lattice disorder of the CCA of silica spheres in polymerized acrylic/methacrylic ester films. The effect of orientation of photocell with respect to the radiation source on Bragg diffraction of CCA indicated the presence of convective stirring in the thin fluid system during the photopolymerization that deleteriously affects the periodic array structures. To devise reproducible and more efficient optical filters, experimental methods to minimize or eliminate convective instabilities in monomeric dispersions during polymerization are suggested. © 1998 Chapman & Hall     

Influence of sea water solution on mortar containing calcium carbonate

Normal Portland cement mortar discs containing precipitated or ground limestone at dosages of 0, 2.5, 5 and 15% were made at water/cement ratios of 0.42 or 0.60. They were hydrated in lime water or sea water solution for periods up to 1 year. The length and modulus of elasticity changes were monitored periodically. Some mortars containing CaCO₃ exhibited more than three times the expansion of the reference in sea water. The expansions were greater in samples containing fine CaCO₃. The modulus of elasticity was especially low for samples containing precipitated CaCO₃ and exposed to sea water.