Pretest in forced circulation molten salt heat transfer loop: Studies with thermia‐B

Molten salts have potential application as an efficient heat transfer medium in a primary and secondary heat exchanger in high temperature next‐generation nuclear power plant. Thermal hydraulic studies are vital for reliable and cost‐effective design of the nuclear power plant. Therefore heat transfer study of molten salts will play a vital role in this area. In this work, an experimental system was designed to study thermal hydraulics of the molten salt system up to 700°C. This work describes the pretest results of the experimental facility for extremely corrosive molten fluoride salts with a simulant thermia‐B as the working fluid. In the present work, the details of the system are discussed and thermal‐hydraulic data for heat transfer fluid thermia‐B has been presented. Experiments were carried out at Reynolds number in the range of 4500 to 40 500 and Prandtl number in the range of 34 to 144. Effect of Reynolds number, melting tank temperature, and heat input to test section on forced convective heat transfer was studied under turbulent conditions. Comparison of the experimental data with different empirical correlations has been presented.     

A Promiscuous Cytochrome P450 Hydroxylates Aliphatic and Aromatic C−H Bonds of Aromatic 2,5-Diketopiperazines

Cytochrome P450 enzymes generally functionalize inert C−H bonds, and thus, they are important biocatalysts for chemical synthesis. However, enzymes that catalyze both aliphatic and aromatic hydroxylation in the same biotransformation process have rarely been reported. A recent biochemical study demonstrated the P450 TxtC for the biosynthesis of herbicidal thaxtomins as the first example of this unique type of enzyme. Herein, the detailed characterization of substrate requirements and biocatalytic applications of TxtC are reported. The results reveal the importance of N-methylation of the thaxtomin diketopiperazine (DKP) core on enzyme reactions and demonstrate the tolerance of the enzyme to modifications on the indole and phenyl moieties of its substrates. Furthermore, hydroxylated, methylated, aromatic DKPs are synthesized through a biocatalytic route comprising TxtC and the promiscuous N-methyltransferase Amir_4628; thus providing a basis for the broad application of this unique P450.     

Green synthetic route of carbon quantum dot-reinforced graphene oxide-poly(vinylidene fluoride-co-hexa fluoropropylene) nanocomposites: Toward high dielectric constant and suppressed loss

A simple and green method was developed to fabricate carbon quantum dot@ graphene oxide filled poly (vinylidene fluoride-co-hexa-fluoropropylene) [CQD@GO-P(VDF-HFP)] nanocomposite films via solution casting technique. The synthetic approach was to bring CQD from bilva leafs, a renewable and sustainable resource. The effect of CQD on dielectric properties, dielectric constant, and dielectric loss in the presence of GO along with P (VDF-HFP) matrix were investigated. The result showed that the nanocomposites having 1.5 wt % of CQD@GO-P(VDF-HFP) with higher dielectric constant (≈144) at 100 Hz and suppressed loss (<1) at 1000 Hz, which is well supported by field emission scanning electron microscopy (FESEM) study. The FESEM study shows a river iceland morphology with a channel-like structure along with voids and pores that may provide a conducting network, which tends to have Maxwell Wagner-Sillars or interfacial polarization results in a high-end properties outcome. Furthermore, the suppressed loss enhanced the possibility of end use performance of CQD@GO-P(VDF-HFP) matrix with a referral memorandum of percolation theory. Thus, the present work demonstrated a new approach to develop high dielectric constant and negligible loss materials in the field of embedded devices for electronic industries through green synthetic approach. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019 , 136, 47850.     

Continuous-time complex band-pass Gm-C sigma delta ADC with programmable bandwidths

Analog Integrated Circuits and Signal Processing - In this paper new continuous-time sigma delta modulator that supports complex band-pass (CBP) architectures with the re-configurable bandwidths of...     

Numerical modelling of second‐grade fluid flow past a stretching sheet

The present numerical study reports the chemically reacting boundary layer flow of a magnetohydrodynamic second‐grade fluid past a stretching sheet under the influence of internal heat generation or absorption with work done due to deformation in the presence of a porous medium. To distinguish the non‐Newtonian behaviour of the second‐grade fluid with those of Newtonian fluids, a very popularly known second‐grade fluid flow model is used. The fourth order momentum equation with four appropriate boundary conditions along with temperature and concentration equations governing the second‐grade fluid flow are coupled and highly nonlinear in nature. Well‐established similarity transformations are efficiently used to reduce the dimensional flow equations into a set of nondimensional ordinary differential equations with the necessary conditions. The standard bvp4c MATLAB solver is effectively used to solve the fluid flow equations to get the numerical solutions in terms of velocity, temperature, and concentration fields. Numerical results are obtained for a different set of physical parameters and their behaviour is described through graphs and tables. The viscoelastic parameter enhances the velocity field whereas the magnetic and porous parameters suppress the velocity field in the flow region. The temperature field is magnified for increasing values of the heat source/sink parameter. However, from the present numerical study, it is noticed that the flow of heat occurs from sheet to the surrounding ambient fluid. Before concluding the considered problem, our results are validated with previous results and are found to be in good agreement.     

Bright Aggregation‐Induced Emission Dots for Dynamic Tracking and Grading of Patient‐Derived Xenografts in Zebrafish

Cancer prognosis will benefit from a scoring system that could grade malignant traits of patient‐derived cells by assessing their growth and metastasis in a living system. Specific tracking of patient‐derived cells requires labeling by contrast agents with good signal‐to‐noise ratio and no specific stain of host tissues. Towards this aim, aggregation‐induced emission (AIE) dots are developed for in vivo cancer tracking with emphasis on reproducible optimized formulation and specific fluorescent labeling of cells that enable enhanced spatial temporal resolution in vivo. The importance of energy‐dependent AIE dots uptake for patient‐derived cell labeling is emphasized to reveal their specific uptake by viable cancer cells. Using optically transparent zebrafish embryo, the ability is demonstrated to follow the engraftment of transplanted AIE dot labeled cells in zebrafish brains over one week. Cells detected outside the brain after 7 d are quantified as metastatic cells. Results from seven clinical samples demonstrate the utility of this methodology to differentiate low engraftment level of benign neoplasms from higher engraftment level and metastasis detected in malignant ovarian cancer specimens. Achieving clinically validated results supports the use of AIE dot labeled patient derived cells in zebrafish xenografts for future cancer prognosis.     

Open‐Shell Donor–Acceptor Conjugated Polymers with High Electrical Conductivity

Conductive polymers largely derive their electronic functionality from chemical doping, processes by which redox and charge‐transfer reactions form mobile carriers. While decades of research have demonstrated fundamentally new technologies that merge the unique functionality of these materials with the chemical versatility of macromolecules, doping and the resultant material properties are not ideal for many applications. Here, it is demonstrated that open‐shell conjugated polymers comprised of alternating cyclopentadithiophene and thiadiazoloquinoxaline units can achieve high electrical conductivities in their native “undoped” form. Spectroscopic, electrochemical, electron paramagnetic resonance, and magnetic susceptibility measurements demonstrate that this donor–acceptor architecture promotes very narrow bandgaps, strong electronic correlations, high‐spin ground states, and long‐range π‐delocalization. A comparative study of structural variants and processing methodologies demonstrates that the conductivity can be tuned up to 8.18 S cm^?1. This exceeds other neutral narrow bandgap conjugated polymers, many doped polymers, radical conductors, and is comparable to commercial grades of poly(styrene‐sulfonate)‐doped poly(3,4‐ethylenedioxythiophene). X‐ray and morphological studies trace the high conductivity to rigid backbone conformations emanating from strong π‐interactions and long‐range ordered structures formed through self‐organization that lead to a network of delocalized open‐shell sites in electronic communication. The results offer a new platform for the transport of charge in molecular systems.     

Influence of growth parameters on the dopant configuration of nitrogen-doped graphene synthesized from phthalocyanine molecules

Synthesis of nitrogen-doped graphene (NDG) via chemical vapor deposition (CVD) using phthalocyanine, a solid precursor containing carbon and nitrogen, is reported. The effect of the growth parameters (temperature, time, and carrier gas) on the surface morphology, dopant configuration, and conductivity of the films was studied. The NDG films were synthesized at different substrate temperatures of 1050 °C, 950 °C, and 850 °C for different growth times of 5–15 min in the presence of an Ar?+?H₂ gas mixture. Significantly, pyrrolic-N type defects are observed predominantly after 5 min of growth time. At 1050 °C, pyrrolic N content is around 45.4% after 5 min of growth which decreased to 24.1% after 15 min of growth, while the graphitic-N content increased from 41.2 to 76% at the same time. It is demonstrated that the conversion of pyrrolic type of nitrogen to graphitic nitrogen defects can be arrested by changing the carrier gas from Ar?+?H₂ to Ar. The pyrrolic-N content increased to 64% by changing the gas from Ar?+?H₂ to Ar at 15 min. The electrolyte gated field-effect transistors were fabricated using the obtained films, and dopant-dependent mobility was observed. The mobility for pyrrolic-N-dominated film is 13.6 cm² V^?1 s^?1 increasing to 62.8 cm² V^?1 s^?1 for graphitic-N-dominated film.