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41.
D. S. Schnur Nicholas Zabaras 《International journal for numerical methods in engineering》1992,33(10):2039-2057
A numerical procedure which integrates optimization, finite element analysis and automatic finite element mesh generation is developed for solving a two-dimensional inverse/parameter estimation problem in solid mechanics. The problem consists of determining the location and size of a circular inclusion in a finite matrix and the elastic material properties of the inclusion and the matrix. Traction and displacement boundary conditions sufficient for solving a direct problem are applied to the boundary of the domain. In addition, displacements are measured at discrete points on the part of the boundary where the tractions are prescribed. The inverse problem is solved using a modified Levenberg-Marquardt method to match the measured displacements to a finite element model solution which depends on the unknown parameters. Numerical experiments are presented to show how different factors in the problem and the solution procedure influence the accuracy of the estimated parameters. 相似文献
42.
Using the data from vendors and open literature, we have constructed a preliminary cost model to predict the cost of liquid hydrogen (LH2) from water electrolysis. The model has been applied to two LH2 plants. Both have a production rate of 10 886 kg day−1. The first plant (Plant 1) consists of a tank-type electrolyzer and a liquefier and runs all day at the base-load (or equivalent base-load) power rate. The second (Plant 2) consists of a tank-type electrolyzer, a liquefier, a compressor, and storage vessels. The electrolyzer and the compressor shall run only during the off-peak hours at the off-peak power rate. However, the liquefier shall run all day at the base-load (or equivalent base-load) power rate. The costs of LH2 from both plants are presented. Unless the base-load power rate is high and the off-peak power rate is substantially low, Plant 1 appears to be economically more feasible than Plant 2. 相似文献
43.
44.
An outline of the characteristics of PEEK and the versatility of its compositional forms (micro and macro composites) are given to illustrate its wide potential for success in engineering applications. Although it is necessary to have particular tabulations of mechanical properties for engineering design, these are seldom available and consequently it is argued that an understanding of stiffness, toughness and strength properties are required to fully exploit available manufacturer's data and thus develop the full potential of PEEK and its composites. Stiffness characteristics are considered in terms of a modulus function which is dependent on time under load and temperature. In its composite forms, whether reinforced with short or continuous fibres, stiffness anistropy can be both considerable and complex, but some empirical ground-rules are apparent. For continuous fibre composites even in the form of complex lay-ups, it is also possible to attempt some stiffness prediction from certain pseudo-elastic constants. Toughness of PEEK and its composites is described in terms of both comparative and intrinsic properties. Instrumented falling weight impact data, particularly as a function of temperature enable some insight into ductile-brittle transitions for the unreinforced material, but crack initiation and crack propagation processes for the various fibre reinforced forms. Intrinsic toughness is described in terms of linear elastic fracture mechanics theory. Strength properties are described for static and dynamic loading configurations. In particular, PEEK and its composites are evaluated for increasing test severities for strength characteristics; stress concentration, loading form and test temperature are considered. 相似文献
45.
People who enact multiple identities behave as if they possess 2 or more selves, each with its own characteristic moods, memories, and behavioral repertoire. Under different names, this phenomenon occurs in many cultures; in North American culture, it is frequently labeled multiple personality disorder (MPD). This article reviews experimental, cross-cultural, historical, and clinical findings concerning multiplicity and examines the implications of these findings for an understanding of MPD. Multiplicity is viewed from a sociocognitive perspective, and it is concluded that MPD, like other forms of multiplicity, is socially constructed. It is context bounded, goal-directed, social behavior geared to the expectations of significant others, and its characteristics have changed over time to meet changing expectations. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
46.
Intraneural injection of 10-20 x 10(6) viable Mycobacterium leprae into the sciatic nerve of normal, unsensitized, Swiss white mice gives rise to a tuberculoid type of granulomatous response in 2 weeks. The same dose of viable M. leprae when injected into the sciatic nerves of unsensitized immunosuppressed mice (T200 x 5R) elicited a macrophage response. When macrophages were systemically immobilized using an intraperitoneal injection of silica quartz dust in normal mice, the lesion produced was of the lepromatous type, suggesting a role for the macrophage in the induction of the tuberculoid type of granulomatous response. In all of these in situ experiments, M. leprae failed to enter the Schwann cells. 相似文献
47.
Oxygen mass transfer calculations in large arteries 总被引:1,自引:0,他引:1
Parkinsonism is characterised by overactive glutamatergic transmission in the cortico-striatal and subthalamo-medial pallidal pathways. Local blockade of glutamatergic transmission in these pathways can alleviate parkinsonian symptoms. The effectiveness of the treatment, however, is often limited by the simultaneous appearance of unwanted side-effects. These side-effects, including ataxia and dissociative anaesthesia, are particularly problematic when N-methyl-D-aspartate (NMDA) antagonists are used. In an attempt to overcome these problems we have attempted to manipulate excitatory amino acid (EAA)-mediated neurotransmission indirectly by targeting the NMDA receptor associated modulatory sites. We review evidence which demonstrates that antagonists for both the NMDA associated glycine and polyamine sites can reverse parkinsonian symptoms when injected intra-cerebrally in both MPTP-treated and bilateral 6-OHDA lesioned marmosets without eliciting unwanted side-effects. We further review preliminary data which suggest that ifenprodil, a polyamine site antagonist, has striking anti-parkinsonian actions in the marmoset. Potential mechanisms of action underlying these effects are discussed in terms of NMDA receptor subtypes and the neuroanatomical locus of action. The anti-parkinsonian efficacy of intra-striatally administered EAA antagonists leads us to question the view of dopamine acting in the striatum as a simple neuromodulator. 相似文献
48.
Miller Ralph R.; Barnet Robert C.; Grahame Nicholas J. 《Canadian Metallurgical Quarterly》1995,117(3):363
The Rescorla-Wagner model has been the most influential theory of associative learning to emerge from the study of animal behavior over the last 25 years. Recently, equivalence to this model has become a benchmark in assessing connectionist models, with such equivalence often achieved by incorporating the Widrow-Hoff delta rule. This article presents the Rescorla-Wagner model's basic assumptions, reviews some of the model's predictive successes and failures, relates the failures to the model's assumptions, and discusses the model's heuristic value. It is concluded that the model has had a positive influence on the study of simple associative learning by stimulating research and contributing to new model development. However, this benefit should neither lead to the model being regarded as inherently "correct" nor imply that its predictions can be profitably used to assess other models. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
49.
Conditioned eyeblink responses are presumably learned in the cerebellum and relayed to motoneurons by way of the red nucleus. Projections from the red nucleus to cerebellar cortex (Larsell's lobule HVI) could be important for shaping temporally adaptive features of the conditioned response. Rabbits that had pipettes containing wheat germ agglutinated horseradish peroxidase (WGA-HRP) implanted unilaterally into HVI showed retrograde labeling of neurons within subregions of the contralateral red nucleus implicated in eyeblink conditioning by lesioning and recording studies. Retrogradely labeled neurons were also observed in the pontine nuclei, inferior olive, and spinal trigeminal nucleus pars oralis. Projections to HVI provide a possible neural substrate for implementing time-derivative computational models of learning in the cerebellum. Time-derivative models are capable of describing the timing and topography of conditioned responses. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
50.
Jonathan Cherneff Robert Logcher Jerome Connor Nicholas Patrikalakis 《Research in Engineering Design》1992,3(4):195-210
A method for machine interpretation of architectural (or other) schematic drawings is presented. The central problem is to build an efficient drawing parser (i.e., a program that identifies the semantic entities, characteristics, and relationships that are represented in the drawing). The parser is built from specifications of the drawing grammar and an underlying spatial model. The grammar describes what to look for, and the spatial model enables the parser to find it quickly. Coupled with existing optical recognition technology, this technique enables the use of drawings directly as: (1) a database to drive various Architecture-Engineering-Construction (AEC) applications; (2) a communication protocol to integrate CAD systems; (3) a traditional user interface. 相似文献