Identification of Human Adenovirus in Respiratory Samples with Luminex Respiratory Virus Panel Fast V2 Assay and Real-Time Polymerase Chain Reaction

In order to compare the last version of the Respiratory Virus Panel (RVP) Fast assay for human Adenovirus (hAdv) detection with a specific real-time polymerase chain reaction (qPCR), which is considered the gold standard for hAdv detection, nasopharyngeal samples collected from 309 children (age range, four months to eight years) with respiratory tract infection were tested using the RVP Fast v2 assay (Luminex Molecular Diagnostics, Inc., Toronto, ON, Canada) and a specific TaqMan qPCR to identify hAdv DNA. The RVP Fast v2 assay detected 30/61 (49.2%) hAdv infections that had been identified by real-time qPCR, demonstrating a significantly lower detection rate (p < 0.001). The sensitivity of the RVP Fast v2 assay in comparison to qPCR was lower in younger children (42.9% vs. 57.7%; Cohen’s kappa coefficient, 0.53); in samples with co-infections (40.0% vs. 56.7%; Cohen’s kappa coefficient, 0.52); and in samples with hAdv type C (45.9% vs. 57.1%; Cohen’s kappa coefficient, 0.60). Samples with lower viral loads were associated with a significantly lower sensitivity of the RVP Fast v2 assay (35.1% vs. 68.2%, p = 0.01; Cohen’s kappa coefficients, 0.49). The RVP Fast v2 assay has important limitations for the detection of hAdv and cannot be used to evaluate whether hAdvs are the main etiologic agent responsible for an outbreak or when epidemiological studies are performed.     

Energy-saving self-configuring networked data centers

In this paper, we develop the optimal minimum-energy scheduler for the dynamic online joint allocation of the task sizes, computing rates, communication rates and communication powers in virtualized Networked Data Centers (NetDCs) that operates under hard per-job delay-constraints. The referred NetDC’s infrastructure is composed by multiple frequency-scalable Virtual Machines (VMs), that are interconnected by a bandwidth and power-limited switched Local Area Network (LAN). Due to the nonlinear power-vs.-communication rate relationship, the resulting Computing-Communication Optimization Problem (CCOP) is inherently nonconvex. In order to analytically compute the exact solution of the CCOP, we develop a solving approach that relies on the following two main steps: (i) we prove that the CCOP retains a loosely coupled structure, that allows us to perform the lossless decomposition of the CCOP into the cascade of two simpler sub-problems; and, (ii) we prove that the coupling between the aforementioned sub-problems is provided by a (scalar) constraint, that is linear in the offered workload. The resulting optimal scheduler is amenable of scalable and distributed online implementation and its analytical characterization is in closed-form. After numerically testing its actual performance under randomly time-varying synthetically generated and real-world measured workload traces, we compare the obtained performance with the corresponding ones of some state-of-the-art static and sequential schedulers.     

Participatory Irrigation Management and Transfer: Setting the Guiding Principles for a Sustaining Monitoring &amp; Evaluation System – a Focus on the Mediterranean

A major shortcoming of Participatory Irrigation Management and Irrigation Management Transfer (PIM/IMT) is the absence of Monitoring & Evaluation (M&E) systems that accompany these processes and become a major instrument to correct, improve and learn. Although at the global level some countries have exerted efforts to implement M&E systems, these still present limitations, as the review of the international experiences shows. The Mediterranean situation is even more dramatic since only Tunisia implements an M&E system, whereas Egypt has shyly moved in this direction with a limited practical application. This state of affairs led the authors to develop a set of guiding principles to develop an M&E system to be applied in countries where PIM/IMT is adopted. This paper revises the main international efforts devoted to assess the performance of PIM/IMT and the state of the art of these processes in Southern and Eastern Mediterranean Countries. Moreover, it sets the framework and analyses the main sustaining factors for the development of a new M&E system for these countries.     

Post-cracking behaviour of steel and macro-synthetic fibre-reinforced concretes

The present paper describes the results of an experimental investigation on the performances of concrete specimens reinforced with either steel or macro-synthetic fibres under three-point bending. Steel fibres are often used to improve the flexural toughness of concrete and are used in various structural applications while synthetic fibres are more often used to reduce crack opening due to shrinkage. Macro-synthetic fibres have been proposed more recently with the aim of creating an alternative to steel fibres in structural applications but their use is still limited.In the tests performed, specimens cast with the same concrete mix, but containing different dosages of either steel or macro-synthetic fibres, were used and compared. In general steel fibres were more efficient in increasing the toughness of concrete than macro-synthetic fibres, even though their results were significantly more scattered.Test results were used to calculate the parameters of stress-crack opening relations via inverse analysis using a cracked hinge model. This numerical model provided results, in terms of force-Crack Mouth Opening Displacement (CMOD) curves, in very good agreement with the experimental data.     

Differential uptake of U,Mo and Cu,by roots,stalks and seeds of oats grown on uranium‐rich soils

The uptake of U, Mo and Cu by oats grown in high uranium containing soils was investigated. Roots of the plant were found to constitute an effective barrier to U uptake, while that of Mo was pH dependent. Cu concentrations in the plant were independent of those of the other two metals.     

Energy supplier obligations and white certificate schemes: Comparative analysis of experiences in the European Union

A number of Member States of the European Union (EU) have introduced market-based policy portfolios based on quantified energy savings obligations on energy distributors or suppliers, possibly coupled with certification of project-based energy savings (via white certificates), and the option to trade the certificates or obligations. The paper provides an up-to-date review and analysis of results to date of white certificate schemes in the EU.     

Effect of flow field design on performances of high temperature PEM fuel cells: Experimental analysis

Among all types of fuel cells, attention is being drawn lately on high temperature Polybenzimidazole (PBI) PEM because their operative temperature range (120-180 °C) increases the tolerance to carbon monoxide. This feature allows working with low quality hydrogen produced by hydrocarbon reformation. Most of the literature on PBI PEM deals with membrane and MEA related issues, however, cell efficiency and specially, commercial feasibility are conditioned by other fuel cell components as bipolar plates. In the present study the focus is on the effect of the flow field geometry of high temperature PBI PEM composite bipolar plates on the overall performance of the cell. For this purpose, three different channel geometries are studied: two serpentine flow fields and parallel channels flow field. Results show that serpentine geometry yields higher performance though it introduces higher pressure drop along the cell as well.     

Defining a complex intervention: The development of demarcation criteria for “meditation”.

The authors used a 5-round Delphi study with a panel of 7 experts in meditation research to achieve agreement on a set of criteria for a working definition of “meditation” for use in a comprehensive systematic review of the therapeutic use of meditation. Participants agreed that essential to a meditation practice is its use of (a) a defined technique, (b) logic relaxation, and (c) a self-induced state. Participants also agreed that a meditation practice may (d) involve a state of psychophysical relaxation somewhere in the process; (e) use a self-focus skill or anchor; (f) involve an altered state/mode of consciousness, mystic experience, enlightenment or suspension of logical thought processes; (g) be embedded in a religious/spiritual/philosophical context; or (h) involve an experience of mental silence. The results of this study provide insight into the challenges faced by researchers who want to demarcate meditative practices from nonmeditative practices, and they describe an approach to this problem that may prove useful for researchers trying to operationalize meditation in the context of comparative research. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Atomic force microscopy as a nanoscience tool in rational food design

Atomic force microscopy (AFM) is a nanoscience tool that has been used to provide new information on the molecular structure of food materials. As an imaging tool it has led to solutions to previously intractable problems in food science. This type of information can provide a basis for tailoring food structures to optimise functional behaviour. Such an approach will be illustrated by indicating how a basic understanding of the role of interfacial stability in complex foods systems can be extended to understand how such interfacial structures behave on digestion, and how this in turn suggests routes for the rational design of processed food structures to modify lipolysis and control fat intake. As a force transducer AFM can be used to probe interactions between food structures such as emulsion droplets at the colloidal level. This use of force spectroscopy will be illustrated through showing how it allows the effect of the structural modification of interfacial structures on colloidal interactions to be probed in model emulsion systems. Direct studies on interactions between colliding soft, deformable droplets reveal new types of interactions unique to deformable particles that can be exploited to manipulate the behaviour of processed or natural emulsion structures involved in digestion processes. Force spectroscopy can be adapted to probe specific intermolecular interactions, and this application of the technique will be illustrated through its use to test molecular hypotheses for the bioactivity of modified pectin molecules. Copyright © 2011 Society of Chemical Industry