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91.
Nanocrystalline Ag/MgO composites were prepared by the ultrafine-powder-compaction method. The structure was investigated for the first time by high-resolution electron microscopy. Nanometre-sized Ag grains and MgO grains in the composites bonded directly without any intermediate phase layer. Certain preferred orientation relationships were observed between the Ag and MgO grains. The nanocrystalline Ag/MgO composites retained their grain size during annealing up to 873 K. Vickers microhardness measurements were performed on the as-compacted and annealed specimens. Generation and propagation of cracks were less active in the nanocrystalline Ag/MgO composites than in a single-phase nanocrystalline MgO. The Vickers microhardness of the nanocrystalline Ag/MgO composites remained up to 1073 K. Hot-pressing deformation tests showed that the nanocrystalline Ag/MgO composites deformed plastically at 1073 K.  相似文献   
92.
The thickness of the glass substrate used in liquid crystal displays continues to be decreased from its original thickness of 1.1 mm for the purpose reducing size and weight. The aim of this study was to clarify the influence of the glass substrate thickness during laser scribing with crack propagation caused by laser heating followed by quick quenching. The laser scribe conditions for soda-lime glass substrates with thickness equal to or less than 1.1 mm were obtained in laser irradiation experiments. Two-dimensional thermal elasticity analysis was conducted with a finite element method based on the scribable conditions obtained in the experiment. The laser scribable conditions can then be estimated by the upper limit of the maximum surface temperature, Tmax, and the lower limit of the maximum tensile stress, σtmax, in the cooling area, regardless of the glass substrate thickness. There is a substrate thickness with which the maximum tensile stress σtmax becomes the largest under each scribe condition. The substrate thickness with which σtmax becomes the largest is obtained at a faster scribe velocity for thinner glass substrate and at slower scribe velocity for thicker glass substrate. Owing to these relations, the crack depth also has almost the same tendency as σtmax.  相似文献   
93.

Background

Recently, manufactured nano/microparticles such as fullerenes (C60), carbon black (CB) and ceramic fiber are being widely used because of their desirable properties in industrial, medical and cosmetic fields. However, there are few data on these particles in mammalian mutagenesis and carcinogenesis. To examine genotoxic effects by C60, CB and kaolin, an in vitro micronuclei (MN) test was conducted with human lung cancer cell line, A549 cells. In addition, DNA damage and mutations were analyzed by in vivo assay systems using male C57BL/6J or gpt delta transgenic mice which were intratracheally instilled with single or multiple doses of 0.2 mg per animal of particles.

Results

In in vitro genotoxic analysis, increased MN frequencies were observed in A549 cells treated with C60, CB and kaolin in a dose-dependent manner. These three nano/microparticles also induced DNA damage in the lungs of C57BL/6J mice measured by comet assay. Moreover, single or multiple instillations of C60 and kaolin, increased either or both of gpt and Spi- mutant frequencies in the lungs of gpt delta transgenic mice. Mutation spectra analysis showed transversions were predominant, and more than 60% of the base substitutions occurred at G:C base pairs in the gpt genes. The G:C to C:G transversion was commonly increased by these particle instillations.

Conclusion

Manufactured nano/microparticles, CB, C60 and kaolin, were shown to be genotoxic in in vitro and in vivo assay systems.  相似文献   
94.
Motile bacteria sense changes in the concentration of chemicals in environments and respond in a behavioral manner. This behavioral response is called chemotaxis. Bacterial chemotaxis can be viewed as an important prelude to metabolism, prey-predator relationships, symbiosis, infections, and other ecological interactions in biological communities. Genome analysis reveals that a large number of environmental motile bacteria possess a number of genes involved in chemosensing and chemotatic signal transduction. Pseudomonas aeruginosa has a very complex chemosensory system with more than 20 chemotaxis (che) genes in five distinct clusters and 26 chemoreceptor (methyl-accepting chemotaxis protein [mcp]) genes. Among the 26 MCPs of P. aeruginosa, nine have been identified as MCPs for amino acids, inorganic phosphate, oxygen, ethylene, and volatile chlorinated aliphatic hydrocarbons, whereas 3 MCPs were demonstrated to be involved in biofilm formation and biosynthesis of type IV pilus. Six che genes are essential for chemotactic responses, while genes in Pil-Chp cluster and Wsp cluster are involved in type IV pilus synthesis and twitching motility and biofilm formation, respectively. P. aeruginosa, with its complex chemotaxis system, is a better model microorganism for investigating ecological aspects of chemotaxis in environmental bacteria than Escherichia coli and Salmonella enterica serovar Typhimurium, which possess a relatively simpler chemotaxis system.  相似文献   
95.
In this paper, we present a stable sound source tracking method based on two updating algorithm. In the method, an eigenvector spanning the signal subspace is updated by using the Projection Approximation Subspace Tracking (PAST) algorithm without the eigen‐decomposition of a correlation matrix. Then, a constrained minimization problem is formulated taking into account the stability, and the solution is determined successively by applying the Interior Point Least Square (IPLS) algorithm. As a result, stable tracking can be achieved without the peak search of a MUltiple SIgnal Classification (MUSIC) spectrum, which often requires enormous computational costs because many complex multiplying operations are involved. Several experimental results in real room environments have demonstrated the high accuracy and the low computational costs of the proposed method. © Institute of Electrical Engineers of Japan. Published by John Wiley & Sons, Inc.  相似文献   
96.
97.
Photonic Network Communications -  相似文献   
98.
Cowden's disease, multiple hamartoma syndrome, is a dominantly inherited disorder characterized by multiple hamartomas of ectodermal, endodermal, and mesodermal origin and also by a high incidence of malignant tumors. Despite many efforts to identify the genetic alterations responsible for the syndrome, the molecular mechanism remains unclear. We report a case of Cowden's disease in which karyotype analysis revealed a small duplication (about 1 Mb) at 15q11-q13. This part of the genome is a region that is deleted in the Prader-Willi/Angelman syndrome and is a "hot spot" of chromosomal duplication.  相似文献   
99.
One often encounters numerical difficulties in solving linear matrix inequality (LMI) problems obtained from H control problems. For semidefinite programming (SDP) relaxations for combinatorial problems, it is known that when either an SDP relaxation problem or its dual is not strongly feasible, one may encounter such numerical difficulties. We discuss necessary and sufficient conditions to be not strongly feasible for an LMI problem obtained from H state feedback control problems and its dual. Moreover, we interpret the conditions in terms of control theory. In this analysis, facial reduction, which was proposed by Borwein and Wolkowicz, plays an important role. We show that the dual of the LMI problem is not strongly feasible if and only if there exist invariant zeros in the closed left-half plane in the system, and present a remedy to remove the numerical difficulty with the null vectors associated with invariant zeros in the closed left-half plane. Numerical results show that the numerical stability is improved by applying it.  相似文献   
100.
Photonic Network Communications - To achieve fast recovery of optical transport networks after a disaster, we investigate a novel scheme enabling cooperation between carriers. Carriers can take...  相似文献   
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