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461.
    
Plasma biochemical analysis remains one of the established ways of monitoring captive marine mammal health. More recently, complementary plasma lipidomic analysis has proven to be a valid tool in disease diagnosis and prevention, with the potential to validate and complement common biochemical analysis, providing a more integrative approach. In this study, we thoroughly characterized the plasma polar lipid content of Tursiops truncatus, the most common cetacean species held under human care. Our results showed that phosphatidylcholine, lysophosphatidylcholine, and sphingomyelins (CerPCho) are the most represented phospholipid classes in T. truncatus plasma. Palmitic, oleic, and stearic acids are the major fatty acid (FA) present esterified to the plasma polar lipids of this species, although some n-3 species are also remarkably present, namely eicosapentaenoic and docosahexaenoic acids. The polar lipidome identified by HILIC LC–MS allowed identifying 304 different lipid species. These species belong to the phosphatidylcholine (103 lipid species), lysophosphatidylcholine (35), phosphatidylethanolamine (71), lysophosphatidylethanolamine (20), phosphatidylglycerol (13), lysophosphatidylglycerol (5), phosphatidylinositol (15), lysophosphatidylinositol (3), phosphatidylserine (6) lysophosphatidylserine (1), and sphimgomyelin (32) classes. This was the first time that the dolphin plasma phospholipid profile was characterized, providing a knowledge that will be important to further understand lipid metabolism and physiological regulation in small cetaceans. Furthermore, this study proved the practicability of the use of plasma lipid profiling for health assessment in marine mammals under human care.  相似文献   
462.
    
An important scheduling function of manufacturing systems is controlled order release. While there exists a broad literature on order release, reported release procedures typically use simple sequencing rules and greedy heuristics to determine which jobs to select for release. While this is appealing due to its simplicity, its adequateness has recently been questioned. In response, this study uses an integer linear programming model to select orders for release to the shop floor. Using simulation, we show that optimisation has the potential to improve performance compared to ‘classical’ release based on pool sequencing rules. However, in order to also outperform more powerful pool sequencing rules, load balancing and timing must be considered at release. Existing optimisation-based release methods emphasise load balancing in periods when jobs are on time. In line with recent advances in Workload Control theory, we show that a better percentage tardy performance can be achieved by only emphasising load balancing when many jobs are urgent. However, counterintuitively, emphasising urgency in underload periods leads to higher mean tardiness. Compared to previous literature we further highlight that continuous optimisation-based release outperforms periodic optimisation-based release. This has important implications on how optimised-based release should be designed.  相似文献   
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Polymethyl methacrylate (PMMA) is a versatile thermoplastic that is well suited for engineering and many common applications. This article presents a study to evaluate the effect of the processing parameters (laser power and cutting velocity) under the quality of the cut of PMMA. A plan of experiments was established considering CO2 laser cutting with prefixed processing parameters in plates of PMMA with 6 mm thickness. The objective was to evaluate the quality of the cut (surface roughness, dimensional precision and heat affected zone-HAZ) in linear and complex 2D cutting. The obtained results show that PMMA in complex 2D cutting presents dimension of HAZ between 0.12 to 0.37 mm, without burr and low surface roughness Ra?<?1 μm. The results present good repeatability.  相似文献   
465.
The primary goal of this research was to determine the potential for denitrification and phosphorus removal of a full-scale sequencing batch reactor (SBR), with and without the use of methanol as an external carbon source. The control SBR, without methanol addition, achieved negligible denitrification. Two denitrification rates were observed in the experimental SBR, with methanol addition, an initial fast rate and a slower second rate. The denitrification rate during the first rate period increased with increasing methanol concentration, until a maximum denitrification rate of approximately 19 mg NOx-N/g MLVSS/day was attained. Following the depletion of the methanol, denitrification reactions probably continued by using the available natural carbon in the influent, resulting in a slower, second denitrification rate. Biological phosphorus uptake and release was significant only in the SBR with methanol addition. Methanol was probably not utilized as the carbon source for the enhanced biological phosphorus removal (EBPR) process. However, methanol addition was critical, since it depleted the available nitrates and thus allowed EBPR to take place.  相似文献   
466.
The aim of this study was to identify determinants of aldehyde and volatile organic compound (VOC) indoor air concentrations in a sample of more than 140 office rooms, in the framework of the European OFFICAIR research project. A large field campaign was performed, which included (a) the air sampling of aldehydes and VOCs in 37 newly built or recently retrofitted office buildings across 8 European countries in summer and winter and (b) the collection of information on building and offices’ characteristics using checklists. Linear mixed models for repeated measurements were applied to identify the main factors affecting the measured concentrations of selected indoor air pollutants (IAPs). Several associations between aldehydes and VOCs concentrations and buildings’ structural characteristic or occupants’ activity patterns were identified. The aldehyde and VOC determinants in office buildings include building and furnishing materials, indoor climate characteristics (room temperature and relative humidity), the use of consumer products (eg, cleaning and personal care products, office equipment), as well as the presence of outdoor sources in the proximity of the buildings (ie, vehicular traffic). Results also showed that determinants of indoor air concentrations varied considerably among different type of pollutants.  相似文献   
467.
Journal of Signal Processing Systems - The increased adoption of DNN applications drove the emergence of dedicated tensor computing units to accelerate multi-dimensional matrix multiplication...  相似文献   
468.
Microsystem Technologies - This paper presents the fabrication of a silicon neural probe using low-cost microfabrication technologies, such as thin-films deposition, blade dicing, and...  相似文献   
469.
470.
该文工作有双重目的:(i)介绍考虑了弹性平面内稳定和二阶受力性能的无支撑单层斜屋顶钢框架的研究结果;(ii)提出、验证并阐述一种有效方法如何用于这种常用类型框架的设计。在完成了(i)给出相应的框架屈曲模式和P-△二阶效应的特点;(ii)给出了计算相应的分支荷载和二阶弯矩的精确方法和近似方法等工作之后,该文将这些概念融合到一种有效的设计方法中。特别要指出的是,很明显,由于椽子的坡度,  相似文献   
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