Computer-assisted measurement of lumbar spine radiographs

RATIONALE AND OBJECTIVES: The authors evaluated a method for obtaining reproducible, reliable measurements from standard lumbar spine radiographs for determining the degree of spondylolisthesis, vertebral body height, intervertebral disk space height, disk space angle, and degree of vertebral body wedging. MATERIALS AND METHODS: Four to six easily defined points were identified on each vertebral body on anteroposterior and lateral plain radiographs of the lumbosacral spine of patients. From these points, the degree of spondylolisthesis, the vertebral body height, the intervertebral disk space height, the disk space angle, and the degree of vertebral body wedging were easily calculated by using well-known geometric relationships. This method requires the use of a personal computer and a standard spreadsheet program but does not require the use of any other specialized radiographic equipment, computer hardware, or custom software. RESULTS: Calculations of intra- and interobserver variability for the measurement of spondylolisthesis, disk space height, disk space angle, and vertebral body height measurement showed that the technique is extremely reproducible. CONCLUSION: This technique may prove useful in the prospective evaluation of potential candidates for lumbar spinal stenosis surgery.     

Simulation and analysis of small and medium size power systemscontaining wind turbines

A method of simulation and analysis of small or medium-sized power systems with high wind penetration is presented. The computer program developed provides the capability to consider separately the existence of wind turbines dispersed on the radial distribution networks or concentrated in wind parks. The repercussions of their operation for the power generation or the distribution system are calculated, taking into account the composition and the reaction of the system loads. The program was applied to the study of the transient behavior of a small power system typical of the ones existing in small- and medium-sized islands in Greece     

Low energy cooling of the White Tower, functioning as a contemporary museum

Historical buildings are of significance not only because they preserve the cultural heritage of nations but also because of their representative character. However, as buildings they not necessarily provide satisfactory comfort and health conditions, despite the fact that they can be high-energy consumers. The Museum of Byzantine Culture in Thessaloniki has decided to convert the White Tower, a six-floor fortress dating back to the 15th century, into a contemporary city museum with means of audiovisual, virtual and information technologies. A study has been carried out in 2005–2006 to determine the possibilities, given the restrictions applying, to implement measures in order to establish and maintain satisfactory thermal comfort and indoor air quality conditions in the White Tower, whilst ensuring its unobstructed function as a contemporary city museum. The measurements and simulations carried out, together with the resulting suggested interventions are discussed in this paper.     

Using cut-through forwarding to retain the real-time properties of Profibus over hybrid wired/wireless architectures

The benefits of wireless extensions in industrial networks are well recognized as long as the integration of the wireless and fieldbus domains will be capable of retaining the real-time and dependability quality of the current wired industrial networking solutions. In this paper, the architecture and the operation of a cut-through forwarding device are described, to be used in broadcasting, hybrid wired/wireless Profibus systems. Analytical models of the delay overhead introduced due to frame forwarding are presented. It is shown that the usage of cut-through forwarding devices relaxes the bit-rate requirements in the radio segments, while it drastically improves the inherent advantages and reduces the drawbacks of hybrid transmission media architectures, which are based on a single Medium Access Control domain.     

Simple method for coating Si (1 0 0) surfaces with ferritin monolayers—Iron oxide quantum dots

With the goal to develop iron oxide quantum dots we developed a simple method to spread horse spleen ferritin monolayers on a Si (1 0 0) surface. Application of atomic force microscopy and spectroscopic ellipsometry showed the existence of regions with dense ferritin monolayers. Application of transmission electron microscopy identified the core of the spread ferritin as FeO nanocrystals.     

Cyclosporine A in the treatment of early rheumatoid arthritis. A prospective, randomized 24-month study

OBJECTIVE: To investigate the efficacy, tolerability and safety of cyclosporine A (CSA) in early rheumatoid arthritis (RA) patients. METHODS: Patients with an early diagnosis of RA, a disease duration of less than 3 years, and without prior disease modifying antirheumatic drug (DMARD) treatment were studied. They randomly received oral CSA (3 mg/kg/day) or oral methotrexate (MTX) (0.15 mg/kg/week). In addition, all patients in both groups received oral prednisone (7.5 mg/day). RESULTS: Fifty-two patients were assigned to the CSA group and 51 to the MTX group. After 24 months of treatment, 48 patients from the CSA group and 48 from the MTX group showed significant clinical improvement. This was evaluated by the duration of morning stiffness, grip strength, the total joint count, joint swelling, and joint tenderness and pain, compared to pre-treatment values. The clinical improvement was also associated with a significant decrease in ESR and CRP values in both groups. No significant radiological deterioration was observed in the CSA patients compared to those treated with MTX after 24 months. Four patients from the CSA group dropped out of the study, two because of a synovitis flare, one because of severe hypertrichosis and one because of severe gingival hyperplasia. Three patients from the MTX group withdrew, one because of disease flare-up and two because of gastrointestinal disturbances. CONCLUSION: Early immunointervention in RA patients appears to be crucial to limit the development of joint damage. Cyclosporine A appears to be effective, well tolerated and safe in the long-term treatment of RA and can therefore be used as a first immunomodulatory drug in the armamentarium for the treatment of RA.     

Denoising of the fetal heart rate signal with non-linear filtering of the wavelet transform maxima

The fetal heart rate (FHR) signal provides valuable information for fetal development and well-being. However, the FHR traces derived from present-day ultrasound cardiotocographs are not of the desired quality. The paper applies the wavelet transform (WT) in order to denoise effectively the FHR signal. The denoising procedure analyses the evolution of the WT maxima across scales. The singularities of the signal create wavelet maxima with different properties from those of the induced noise. Since it is difficult to formulate precise rules that distinguish between the wavelet maxima of the FHR signal from those of the noise we have trained a neural network for this classification task. The neural network draws out successfully the noise induced wavelet maxima. An improved FHR signal can be obtained from the coarser wavelet approximation signal component and the filtered wavelet maxima by means of the inverse dyadic wavelet transform. Also, feature extraction and processing algorithms can be defined on the denoised wavelet coefficients (instead of on the original signal).     

The non-linear solution of the mixed-mode caustics in birefringent materials

The purpose of this note is to study the transmitted and rear face reflected caustics in birefringent plates for a mixed-mode stress field at the crack tip.     

Light-weight multicast services (LMS): a router-assisted scheme for reliable multicast

Building on the success of unicast IP, IP Multicast adopted a simple, open, best-effort delivery model with many-to-many semantics. Despite several years of effort, a general, scalable and reliable end-to-end transport protocol analogous to TCP has proven elusive. Proposed solutions are either inflexible, or incur high control overhead. We present Lightweight Multicast Services (LMS), which enhance the IP Multicast model with simple forwarding services to facilitate scalable and efficient (compared to pure end-to-end) solutions to problems such as reliable multicast. In LMS, routers tag and steer control packets to preselected endpoints and perform fine-grain multicast to guide responses to a subset of the group without transport-level processing. LMS divides error control into transport and forwarding components, which allows the former to remain at the end-points while the latter is pushed to the routers, where it can be implemented very efficiently. The division is clean, resulting in significant gains in performance and scalability, while reducing application complexity. LMS reaches beyond reliable multicast to applications such as scalable collect, any-cast, and in general, any application that can benefit from a hierarchy congruent with the underlying topology.