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41.
A patient with Guillain-Barré syndrome is reported on who responded favourably to a short course treatment with the novel immunosuppressant sodium fusidate (Fucidin), given at a daily dose of 1.5 g for one week. Along with prompt and clear cut clinical improvement, treatment with Fucidin was associated with a rapid decline in the blood concentrations of inflammatory cytokines presumably implicated in the pathogenesis of Guillain-Barré syndrome such as interleukin-2, interferon-gamma, and tumor necrosis factor-alpha. The ex vivo production of these cytokines was also markedly diminished compared with pretreatment values. Fucidin was well tolerated and no clinical or biochemical side effects were seen.  相似文献   
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The variance of least squares estimators for the parameter estimation of a damped sinusoidal process is analyzed, based on first-order perturbation. Analytical expressions for the variances of the frequency, damping factor, amplitude, and phase estimators are derived. Explicit expressions are given for both damped and undamped single-mode cases. The effect of mode separation on the accuracy is investigated through the two-mode case. The dependence of the variances on number of data points, model order, signal-to-noise ratio, and mode separation is investigated, both analytically and numerically, for practical applications. Extensive Monte Carlo simulation results are given to verify, enhance, and illustrate the analytical expressions  相似文献   
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BACKGROUND: A patient was diagnosed with an extramedullary plasmacytoma of the lung after complete resection of the mass at thoracotomy. Immunoperoxidase staining of the mass revealed monoclonal lambda chains. Screening for multiple myeloma identified a small amount of M-protein in the blood, but no other evidence of multiple myeloma was found. METHODS: A literature search was conducted to determine the prognosis and the best way to manage the patient. RESULTS: Nineteen cases of primary pulmonary plasmacytoma were found in the literature. The age range was 3-79 years. Most of these cases were diagnosed at thoracotomy and treated by surgical excision. Immunohistochemical evaluation of the lesion is essential for diagnosis but was done in only three cases. CONCLUSIONS: Surgery and radiation therapy seem to be equally effective forms of treatment. The role of adjuvant chemotherapy is unknown. Local recurrences are rare. Follow-up data were inadequate to determine disease-free survival, progression to multiple myeloma, and overall survival in primary pulmonary plasmacytoma. Close follow-up is needed to detect progression.  相似文献   
46.
Journal of Electroceramics - Hematite (α-Fe2O3) nanoparticles were synthesized by modified solution combustion method using a mixture of hexamethylenetetramine (HMTA) and glycine fuels at fuel...  相似文献   
47.
The paper investigates the uplift performance of horizontal anchor plate in geocell reinforced sand through a series of model tests. It is noted that the unreinforced anchor plate undergoes a clear failure at a displacement of about 3% of its width, whereas with the provision of geocell and a layer of geotextile right below the geocell mattress significantly increases the uplift capacity by about 4.5 times higher than that of unreinforced sand and could sustain anchor displacement of more than 60%. Results indicates that the geocell mattress by virtue of its rigidity distributes the uplift load in the lateral directions to a larger area, thereby reducing the stress in the overlying soil mass and hence increases the performance of anchor plate system. The provision of the additional geotextile layer right below the geocell mattress is found to be very effective in increasing the stiffness as well as load carrying capacity of anchor plate system. The optimum size (i.e., width and length) of geocell mattress giving adequate load carrying capacity of anchor plate is found to be 5.4 times of anchor width (5.4B). The comparison of model tests results with 3D numerical analysis shows good agreement, indicating that the proposed model is able to capture the uplift load-displacement behaviour of geocell reinforced anchor plate system.  相似文献   
48.
In recent times, the images and videos have emerged as one of the most important information source depicting the real time scenarios. Digital images nowadays serve as input for many applications and replacing the manual methods due to their capabilities of 3D scene representation in 2D plane. The capabilities of digital images along with utilization of machine learning methodologies are showing promising accuracies in many applications of prediction and pattern recognition. One of the application fields pertains to detection of diseases occurring in the plants, which are destroying the widespread fields. Traditionally the disease detection process was done by a domain expert using manual examination and laboratory tests. This is a tedious and time consuming process and does not suffice the accuracy levels. This creates a room for the research in developing automation based methods where the images captured through sensors and cameras will be used for detection of disease and control its spreading. The digital images captured from the field's forms the dataset which trains the machine learning models to predict the nature of the disease. The accuracy of these models is greatly affected by the amount of noise and ailments present in the input images, appropriate segmentation methodology, feature vector development and the choice of machine learning algorithm. To ensure the high rated performance of the designed system the research is moving in a direction to fine tune each and every stage separately considering their dependencies on subsequent stages. Therefore the most optimum solution can be obtained by considering the image processing methodologies for improving the quality of image and then applying statistical methods for feature extraction and selection. The training vector thus developed is capable of presenting the relationship between the feature values and the target class. In this article, a highly accurate system model for detecting the diseases occurring in citrus fruits using a hybrid feature development approach is proposed. The overall improvement in terms of accuracy is measured and depicted.  相似文献   
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Abstract

This article discusses the bias of the growing constituency of civil society activists in India against conventional water management solutions implemented by the government, and the ‘alternatives’ they champion, which force the government to enter into an endless debate with these groups. The article goes into the fundamental reasons for this bias, and identifies four types of civil society activist: ‘professional’, ‘ideologue’, ‘romantic’ and ‘doomsday prophet’. The article also argues that water bureaucracies in India should adopt evidence-based policy making, subjecting the ‘alternatives’ to the same degree of scrutiny as the conventional ones, to end the policy dilemma, while enhancing the overall quality of design, execution and management of projects for better outcomes.  相似文献   
50.

In this study, we report the fabrication of cadmium-doped indium sulfide thin films (In2S3:Cd) using a low-cost nebulizer-aided spray pyrolysis process at 350 °C on glass substrates for photo-sensing applications. The impact of 0, 2, 4, and 8 wt% cadmium concentrations on the structure, morphology, optical properties, and photo-sensing capabilities of In2S3 thin films were examined systematically. From X-ray diffraction (XRD) analysis, the major peak is located in the (103) plane for all Cd-doped In2S3 thin film samples, and the maximum crystallite size for the 4 wt% sample is 59 nm. The field emission scanning electron microscope (FESEM) image revealed a homogenous large-grained surface of Cd-doped In2S3 film that completely covered the substrate. UV–Vis absorption analysis demonstrated good absorption for all thin film samples in the visible and ultraviolet regions of the electromagnetic spectrum, particularly, the 4% Cd-doped concentration showed excellent absorption as is observed from Tauc relation. The highest PL intensity at 680 nm was observed for the sample coated with 4 wt% of Cd. Under UV light, the IV behavior depicts a light current of 1.06?×?10–6 A for a 5 V bias voltage. The In2S3: Cd (4%) sample had the highest responsivity of 2.12?×?10?1A/W and a detectivity of 1.84?×?1011 Jones, with a high EQE of 50%. The study manifests that the developed Cd (4%)-doped In2S3 thin film sample might be better suited for the application of photodetectors.

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