Remotely Controlled Red Blood Cell Carriers for Cancer Targeting and Near‐Infrared Light‐Triggered Drug Release in Combined Photothermal–Chemotherapy

Red blood cells (RBCs), the “innate carriers” in blood vessels, are gifted with many unique advantages in drug transportation over synthetic drug delivery systems (DDSs). Herein, a tumor angiogenesis targeting, light stimulus‐responsive, RBC‐based DDS is developed by incorporating various functional components within the RBC platform. An albumin bound near‐infrared (NIR) dye, together with a chemotherapy drug doxorubicin, is encapsulated inside RBCs, the surfaces of which are modified with a targeting peptide to allow cancer targeting. Under stimulation by an external NIR laser, the membrane of the RBCs would be destroyed by the light‐induced photothermal heating, resulting in effective drug release. As a proof of principle, RBC‐based cancer cell targeted drug delivery and light‐controlled drug release is demonstrated in vitro, achieving a marked synergistic therapeutic effect through the combined photothermal–chemotherapy. This work presents a novel design of smart RBC carriers, which are inherently biocompatible, promising for targeted combination therapy of cancer.     

Unraveling the Reasons for Efficiency Loss in Perovskite Solar Cells

The effect of the presence of unreacted PbI₂ on the perovskite solar cells efficiency is reported. N,N‐Dimethylformamide vapor treatment is introduced to study the influence of complete conversion to a power conversion efficiency of the device. It is discovered that the optimized morphology of the PbI₂ under layer is essential to form a dense perovskite layer preventing recombination by direct contact between TiO₂ and a hole transporting layer, and to increase the charge collection efficiency. The present findings provide an insight into the morphology and growth mechanism of perovskite layer, the correlation between the device performance, and the film deposition process.     

Magnetically Modulated Pot‐Like MnFe2O4 Micromotors: Nanoparticle Assembly Fabrication and their Capability for Direct Oil Removal

This work demonstrates a simple‐structured, low‐cost magnetically modulated micromotor of MnFe₂O₄ pot‐like hollow microparticles as well as its facile, versatile, and large‐scale growing‐bubble‐templated nanoparticle (NP) assembly fabrication approach. In this approach, the hydrophobic MnFe₂O₄@oleic acid NPs in an oil droplet of chloroform and hexane assembled into a dense NP shell layer due to the hydrophobic interactions between the NP surfaces. With the encapsulated oil continuously vaporizing into high‐pressured gas bubbles, the dense MnFe₂O₄ NP shell layer then bursts, forming an asymmetric pot‐like MnFe₂O₄ micromotor by creating a single hole in it. For the as‐developed simple pot‐like MnFe₂O₄ micromotor, the catalytically generated O₂ molecules nucleate and grow into bubbles preferentially on the inner concave surface rather than on the outer convex surface, resulting in continuous ejection of O₂ bubbles from the open hole to propel it. Dexterously integrating the high catalytic activity for H₂O₂ decomposition to produce O₂ bubbles, excellent magnetic property with the instinctive surface hydrophobicity, the MnFe₂O₄ pot‐like micromotor not only can autonomously move in water media with both velocity and direction modulated by external magnetic field but also can directly serve for environmental oil removal without any further surface modification. The results here may inspire novel practical micromotors.     

光网络的保护策略

对光网络中的保护方法进行分类描述,结合当前的研究状况,对光网络保护算法的研究方向,提出相关见解.     

二维目标电磁散射计算的一种高精度有限元-边界元混合方法

给出了应用于二维目标电磁散射计算的一种高精度有限元-边界元混合方法:1)将八结点曲边四边形二阶等参数单元作为有限元单元,2)运用插值函数法简单而又高精度地计算边界元部分采用二阶单元时的奇异积分。通过数值实验验证了方法的有效性。     

Saliency guided self-attention network for pedestrian attribute recognition in surveillance scenarios

Pedestrian attribute recognition is often considered as a multi-label image classification task. In order to make full use of attribute-related location information, a saliency guided sel-attention network ( SGSA-Net) was proposed to weakly supervise attribute localization, without annotations of attribute-related regions. Saliency priors were integrated into the spatial attention module ( SAM ). Meanwhile,channel-wise attention and spatial attention were introduced into the network. Moreover, a weighted binary cross-entropy loss ( WCEL) function was employed to handle the imbalance of training data. Extensive experiments on richly annotated pedestrian ( RAP) and pedestrian attribute ( PETA) datasets demonstrated that SGSA-Net outperformed other state-of-the-art methods.     

基于激光雷达的无人机在杆塔附近的定位研究

对于我国电网现行高压输电线路的巡检方式,主要是通过人工手持仪器或肉眼来巡查设施缺陷的,不仅条件艰苦,强度大,而且效率低,已不能适应现代化电网的安全运行和发展.近些年,随着无人机技术以及相关传感器技术的快速发展,无人机在电力巡检方面有着更加广泛的应用.鉴于此,提出一种基于激光雷达与无人机的高压电塔附近的实时定位与地图构建...     

激光横风测量技术的研究

基于激光在湍流大气中的光强闪烁现象搭建了一套横风测量系统,并提出了一种趋势匹配算法.对拟合后激光回波信号的趋势序列进行匹配,计算两束回波信号的相关时间时延,并反演出整条路径上的合成风速.用该系统与标准测风雷达分别对117、225、485m的目标路径进行同步测量,实验结果表明,两台设备的测量数据具有较好的一致性,相关系数...     

Hierarchical NiS2 Modified with Bifunctional Carbon for Enhanced Potassium‐Ion Storage

Potassium‐ion batteries (PIBs) are currently drawing increased attention as a promising alternative to lithium‐ion batteries (LIBs) owing to the abundant resource and low cost of potassium. However, due to the large ionic radius size of K⁺, electrode material that can stably maintain K⁺ insertion/deintercalation is still extremely inadequate, especially for anode material with a satisfactory reversible capacity. As an attempt, nitrogen/carbon dual‐doped hierarchical NiS₂ is introduced as the electrode material in PIBs for the first time. Considering that the introduction of the carbon layer effectively alleviates the volume expansion of the material itself, further improves the electronic conductivity, and finally accelerates the charge transfer of K⁺, not surprisingly, NiS₂ decorated with the bifunctional carbon (NiS₂@C@C) material electrode shows excellent potassium storage performances. When utilized as a PIB anode, it delivers a high reversible capacity of 302.7 mAh g^?1 at 50 mA g^?1 after 100 cycles. The first coulombic efficiency is 78.6% and rate performance is 151.2 mAh g^?1 at 1.6 A g^?1 of the NiS₂@C@C, which are also notable. Given such remarkable electrochemical properties, this work is expected to provide more possibilities for the reasonable design of advanced electrode materials for metal sulfide potassium ion batteries.