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81.
82.
开发CGF的难点和重点在于CGF实体行为的生成,尤其是人类智能行为的实现。人类行为建模最重要的三个方面是知识获取、知识表示和决策机制,都与人工智能技术相关。该文主要介绍人类行为描述的知识表示和知识获取问题,讨论了人工智能技术在这两个方面的应用,并对将来的研究工作做了一个简单的展望。 相似文献
83.
某尾矿库周围环境中污染物生态转移研究 总被引:4,自引:0,他引:4
对我国某尾矿库周围环境中放射性核素U、^226Ra、Th及非放污染物Mn^2 、Cd、Cr、Pb在农作物和水生生物等介质中的浓集情况进行了现场研究,给出了相应的污染物生态学转移系数Bv和Bp值。 相似文献
84.
85.
The accurate targeting of secretory vesicles to distinct sites on the plasma membrane is necessary to achieve polarized growth and to establish specialized domains at the surface of eukaryotic cells. Members of a protein complex required for exocytosis, the exocyst, have been localized to regions of active secretion in the budding yeast Saccharomyces cerevisiae where they may function to specify sites on the plasma membrane for vesicle docking and fusion. In this study we have addressed the function of one member of the exocyst complex, Sec10p. We have identified two functional domains of Sec10p that act in a dominant-negative manner to inhibit cell growth upon overexpression. Phenotypic and biochemical analysis of the dominant-negative mutants points to a bifunctional role for Sec10p. One domain, consisting of the amino-terminal two-thirds of Sec10p directly interacts with Sec15p, another exocyst component. Overexpression of this domain displaces the full-length Sec10 from the exocyst complex, resulting in a block in exocytosis and an accumulation of secretory vesicles. The carboxy-terminal domain of Sec10p does not interact with other members of the exocyst complex and expression of this domain does not cause a secretory defect. Rather, this mutant results in the formation of elongated cells, suggesting that the second domain of Sec10p is required for morphogenesis, perhaps regulating the reorientation of the secretory pathway from the tip of the emerging daughter cell toward the mother-daughter connection during cell cycle progression. 相似文献
86.
采用钻孔灌注桩作为深地坑的围护结构,在坑内设排水沟、集水井排水。成功地在珠江三角洲地区狭窄场地进行地坑开挖,既保证了工程质量又有其特色。 相似文献
87.
高韧性—70℃低温钢WHD4(09MnNiDR)的性能及应用 总被引:1,自引:0,他引:1
本文研究了武钢研制生产的高韧性—70℃低温钢WHD4(09MnNiDR)钢板的全面力学性能、焊接性能.介绍该钢在大型石油、化工设备中的应用实例.结果表明该钢具有优异的低温韧性和优良的焊接性能,是制造低温压力容器等设备的理想用材. 相似文献
88.
Postnatal development and myocardial hypertrophy are associated with alterations in cardiac voltage-gated K+ channels. To investigate mechanisms underlying this K+ channel remodeling, expression of Kv4.2 and Kv1.4 K+ channel alpha-subunits was examined in cultured newborn rat ventricular myocytes by Western blot analysis using polyclonal antibodies against each of the subunits. At day 5 of cell culture, Kv1.4 protein was expressed at higher level than Kv4.2; as the age of culture progressed, Kv1.4 was significantly diminished while Kv4.2 increased with time in culture and became the predominant K+ channel protein. Such K+ channel isoform switch from Kv1.4 to Kv4.2 resembles that of the development in vivo. A 72-h treatment with exogenous triiodothyronine (T3, 0.1 microM) to cultured neonatal myocytes enhanced the expression of Kv4.2 by 73% and decreased the Kv1.4 expression by 22%. The effects of T3 were associated with an increase in the protein-to-DNA ratio indicating myocyte hypertrophy. On the other hand, a 72-h treatment with cardiac non-myocyte cell (NMC)-conditioned growth medium (NCGM) or phenylephrine (20 microM) induced similar cell hypertrophy, but in sharp contrast to T3, both markedly suppressed the Kv4.2 channel protein level. In addition, the trophic and the Kv4.2-downregulating effects of NCGM could be mimicked by exogenous endothelin-1 (0.1 microM), a paracrine factor secreted from cardiac NMCs. Our observations for the first time suggest that cardiac Kv4.2 and Kv1.4 K+ channel alpha-subunits are differentially regulated by a variety of myocardial hypertrophic factors. That T3 accelerated the developmental K+ channel isoform switch from Kv1.4 to Kv4.2 in vitro indicates the critical importance of thyroid hormone in postnatal K+ channel remodeling. Cardiac NMCs and alpha-adrenoceptor activation may contribute to the reduced outward K+ channel density in hypertrophied cardiomyocytes. 相似文献
89.
层次式级联多网络模型及其性能 总被引:1,自引:1,他引:0
本文提出了一种层次式级联多网络结构,论述了其训练算法,并验证了该结构的收敛性。这种结构在处理高阶非线性分布数据的分类问题方面具有优良的性能,用北京谱仪事例过滤进行性能测试结果表明,其训练和泛化性能都优于单个BP网络。 相似文献
90.
The mouse GABA transporter (mGAT1) gene has been shown to be exclusively expressed in brain by Northern and Western blot analyses. The interactions between the 5' flanking region of the mGAT1 gene and nuclear proteins from different mouse tissues were studied by means of gel-shift assay. Our results show that nuclear protein factors from non-nervous tissues can specifically recognize a 37 bp sequence that is conserved in the 5' flanking region between the human and mouse GAT1 genes. Similar nuclear protein factors were also found to exist in rat, rabbit and pig. 相似文献