Superparamagnetic Twist‐Type Actuators with Shape‐Independent Magnetic Properties and Surface Functionalization for Advanced Biomedical Applications

Directed nanoparticle self‐organization and two‐photon polymerization are combined to enable three‐dimensional soft‐magnetic microactuators with complex shapes and shape‐independent magnetic properties. Based on the proposed approach, single and double twist‐type swimming microrobots with programmed magnetic anisotropy are demonstrated, and their swimming properties in DI‐water are characterized. The fabricated devices are actuated using weak rotating magnetic fields and are capable of performing wobble‐free corkscrew propulsion. Single twist‐type actuators possess an increase in surface area in excess of 150% over helical actuators with similar feature size without compromising the forward velocity of over one body length per second. A generic and facile combination of glycine grafting and subsequent protein immobilization exploits the actuator's increased surface area, providing for a swimming microrobotic platform with enhanced load capacity desirable for future biomedical applications. Successful surface modification is confirmed by FITC fluorescence.     

Impact of the access network topology on the handoff performance

Micromobility protocols such as Cellular IP, Hawaii and Hierarchical Mobile IP are developed to solve problems of high handoff latency and control overhead, which occur when Mobile IP is used in combination with frequent handoffs. Up to now, tree access network topologies are considered to evaluate the protocol performance. However, for reasons of robustness against link failures and load balancing, extra uplinks and mesh links in the topology are desired. This article makes a classification of several topology types and gives a model that points out to which extent the topology influences the protocol performance in terms of handoff latency and handoff packet loss. Simulations confirm the results calculated by the model. Performance metrics such as load balancing, end-to-end delay and robustness against link failures are also evaluated. The study points to several shortcomings of the existing micromobility protocols for different topology types. Several aspects of the studied handoff schemes, their advantages and drawbacks are identified. L. Peters is a Research Assistant of the Fund for Scientific Research – Flanders (F.W.O.-V., Belgium) Liesbeth Peters was born in Temse, Belgium, in 1978. She received her Master of Science degree in Electrotechnical Engineering from Ghent University, Gent, Belgium in 2001. Since August 2001, she has been working as a doctoral researcher with the Department of Information Technology (INTEC) of the Faculty of Applied Sciences, Ghent University, where she joined the Broadband Communications Networks Group. Since October 2002, she works there as a research assistant of the Fund for Scientific Research—Flanders (F.W.O.-V., Belgium). Her current research interests are in broadband wireless communication and the support of IP mobility in wired cum wireless networks. Ingrid Moerman was born in Gent, Belgium, in 1965. She received the degree in Electro-technical Engineering and the Ph.D degree from the Ghent University, Gent, Belgium in 1987 and 1992, respectively. Since 1987, she has been with the Interuniversity Micro-Electronics Centre (IMEC) at the Department of Information Technology (INTEC) of the Ghent University, where she conducted research in the field of optoelectronics. In 1997, she became a permanent member of the Research Staff at IMEC. Since 2000 she is part-time professor at the Ghent University. Since 2001 she has switched her research domain to broadband communication networks. She is currently involved in the research and education on broadband mobile & wireless communication networks and on multimedia over IP. Her main research interests related to mobile & wireless communication networks are: adaptive QoS routing in wireless ad hoc networks, personal networks, body area networks, wireless access to vehicles (high bandwidth & driving speed), protocol boosting on wireless links, design of fixed access/metro part, traffic engineering and QoS support in the wireless access network. Ingrid Moerman is author or co-author of more than 300 publications in the field of optoelectronics and communication networks. Bart Dhoedt received a degree in Engineering from the Ghent University in 1990. In September 1990, he joined the Department of Information Technology of the Faculty of Applied Sciences, University of Ghent. His research, addressing the use of micro-optics to realize parallel free space optical interconnects, resulted in a PhD degree in 1995. After a 2 year post-doc in opto-electronics, he became professor at the Faculty of Applied Sciences, Department of Information Technology. Since then, he is responsible for several courses on algorithms, programming and software development. His research interests are software engineering and mobile & wireless communications. Bart Dhoedt is author or co-author of more than 100 papers published in international journals or in the proceedings of international conferences. His current research addresses software technologies for communication networks, peer-to-peer networks, mobile networks and active networks. Piet Demeester finished his PhD thesis at the Department of Information Technology (INTEC) at the Ghent University in 1988. At the same department he became group leader of the activities on Metal Organic Vapour Phase Epitaxial growth for optoelectronic components. In 1992 he started a new research group on Broadband Communication Networks. The research in this field resulted in already more than 300 publications. In this research domain he was and is a member of several programme committees of international conferences, such as: ICCCN, the International Conference on Telecommunication Systems, OFC, ICC, and ECOC. He was Chairman of DRCN’98. In 2001 he was chairman of the Technical Programme Committee ECOC’01. He was Guest Editor of three special issues of the IEEE Communications Magazine. He is also a member of the Editorial Board of the Journals “Optical Networks Magazine” and “Photonic Network Communications”. He was a member of several national and international PhD thesis commissions. Piet Demeester is a member of IEEE (Senior Member), ACM and KVIV. His current research interests include: multilayer networks, Quality of Service (QoS) in IP-networks, mobile networks, access networks, grid computing, distributed software, network and service management and applications (supported by FWO-Vlaanderen, the BOF of the Ghent University, the IWT and the European Commission). Piet Demeester is currently full-time professor at the Ghent University, where he is teaching courses in Communication Networks. He has also been teaching in different international courses.     

Mobility management approaches for SDN-enabled mobile networks

The evolving network technologies aim at meeting the envisioned communication demands of future smart cities and applications. Although software-defined networking (SDN) enables flexible network control, its applicability to mobile networks is still in its infancy. When it comes to introducing the SDN vision to mobile networks, handling of wireless events and mobility management operations stand out as major challenges. In this paper, we study the scalability issues of SDNized wireless networks, specifically those relevant to mobility management. We design and implement different mobility management approaches in SDNized wireless networks and investigate the impact of various system variables on the overall handover delays. We also study the improvements in handover delays: (i) when a proposed proactive mobility management algorithm is implemented; (ii) when the controller delegates partial control of mobility management to the forwarding entities. For the implementation of the proposed approaches on the OpenFlow network, the paper also suggests potential extensions to the OpenFlow protocol. The contributed approaches are validated on a full-scale demonstrator, with results showing that proactive outperforms reactive and that the delegated control approach performs better than proactive for smaller topology sizes. Furthermore, a proposal for LTE X2-specific control delegation is discussed as a use case.     

Milk yield, feed intake, prolactin, growth hormone, and glucocorticoid response of cows to supplemented light

Milk production and dry matter intake of 21 cows subjected to 16 h of fluorescent light and 8 h dark and of 21 cows subjected to natural light 9 to 12 h daily between October 25 and March 14 were measured beginning in early (37 to 74 days postpartum) and late (94 to 204 days postpartum) lactation. Cows that received 16 h of fluorescent light produced 6.7% (1.4 kg) more milk per day (adjusted for parity and pretreatment production) than cows exposed to natural photoperiods. Increases of milk production with 16 h of fluorescent light were similar for early and late lactation. Photoperiod did not alter percent of fat in milk. Dry matter intake increased 6.1% for cows in 16 h of light, and this increase could account for increased milk yields. Basal prolactin in serum and that released by thyrotropin releasing hormone were 1.5 to 1.8 times greater for cows exposed to 16 h of light than for cows in 9 to 12 h of natural light daily. Photoperiod did not affect release of prolactin by milking. Cold ambient temperatures reduced basal prolactin and prolactin released by thyrotropin releasing hormone but had no effect on concentrations of growth hormone or glucocorticoids. Compared with cows in late lactation, cows in early lactation released 2.4 times more prolactin after milking, but they released similar amounts of prolactin after thyrotropin releasing hormone. Photoperiod did not affect concentrations of growth hormone or glucocorticoids in blood sera.     

Fiber optic sensing for ultrasonic NDE

An innovative approach to nondestructive evaluation (NDE) using noncontacting optical sensors has demonstrated. In this effort a single mode optical fiber interferometer (OFI) was used to sense the presence and form of Rayleigh waves traveling along the surface of a steel test bar at a velocity of nearly 3mm/µs. Acousto-optic time-domain data was successfully used to detect the presence and locate the position of a test flaw (a machined slot) in the bar, and spectrum analysis was used to estimate its geometry and size. This approach has many potential applications in the ultrasonic evaluation of real flaws in structures with complex geometries. Coupled with the authors' earlier work demonstrating the feasibility of generating acoustic waves in metals using laser light pulses transmitted through the fiber optic probes, this latest achievement points to the development of a fully noncontacting, fiber optic based thermal-acousto-photonic (TAP) NDE system, with potential applications to the reliability testing of many important structures where composition, scale, geometry, or restricted access preclude the use of conventional NDE techniques.     

Smoking cessation may not improve quality of life in atherosclerotic patients.

The benefits of smoking cessation on patients' medical conditions are well documented. Cardiovascular patients who quit smoking significantly reduce their risk of a new event compared with those who continue smoking. Several studies have found that smoking is related to poor quality of life (QoL). In cardiovascular patients, however, less attention has been given to the effect of smoking cessation on patients' QoL. The present study examined the extent to which smoking cessation leads to changes in QoL in these patients within the first year of follow-up. Data were collected in the context of a randomized clinical trial. Smoking outpatients (N = 346) with atherosclerotic disease were included and received medical treatment. They were randomized to receive either nicotine replacement therapy (NRT) or NRT plus a behavioral intervention meant to promote smoking cessation. At baseline, sociodemographic and clinical characteristics were established. Generic and disease-specific QoL as well as smoking status were assessed at baseline and with three follow-up measurements. Multilevel modeling showed that generic and disease-specific QoL in atherosclerotic patients improved significantly within the first year of follow-up. No main differences were found between quitters and smokers in terms of improvement in QoL. In fact, some subgroups reported a poorer QoL after smoking cessation: More highly educated patients reported lower general QoL (p < .05), and patients suffering from coronary artery disease who had a low level of education (p < .01) and patients suffering from peripheral arterial disease who had low nicotine dependency (p < .01) reported lower disease-specific QoL. Atherosclerotic patients' QoL improved significantly but was not enhanced by smoking cessation activities.     

Food hygiene and hazard analysis critical control point in the United Kingdom food industry: practices, perceptions, and attitudes.

A mail survey was designed and distributed to 1,650 managers of food businesses across the manufacturing, retail, and catering sectors of the United Kingdom food industry. Respondents were asked about the food hygiene practices of their business, their use of systems such as hazard analysis critical control point (HACCP), and their attitudes toward a range of food hygiene-related issues. Complete responses were received from 254 businesses, a response rate of 15.3%. The results showed that 69% of manufacturers were using HACCP systems, significantly more than the 13% and 15% in the retail and catering sectors, respectively (P < 0.05); 53% of manufacturing, 59% of retail, and 48% of catering managers thought that their business represented a low risk to food safety. Among businesses using HACCP, specific training in the system was significantly related to the likelihood that businesses had adopted all seven of the HACCP principles (P < 0.05). Business size was a significant factor in the use of HACCP in both the manufacturing and retail sectors. Higher levels of food hygiene qualifications among business managers, business status, and higher perceptions among managers of the risk to food safety of the business were also significantly related to HACCP use in all sectors (P < 0.05). The results from this survey have implications for the future development of HACCP, particularly within the UK retail and catering sectors. Risk communication and training are highlighted as areas of concern for marketing HACCP within these industry sectors.     

A simple method for calculating left ventricular functions from angiographic data using a programmable hand calculator

The end diastolic volume and systolic ejection fraction have gained increasing acceptance as important indicators of ventricular performance. Time consuming calculations and lack of computer facilities have hindered the emergence of these calculations as a routine part of cardiac catheterization studies. The introduction of the programmable hand calculator has provided means for rapid analysis of ventricular volume data in an efficient and inexpensive manner. In this paper the step-by-step procedure for programming the hand calculator is given, as well as instructions for entering raw data and obtaining final calculations. Programs are given for both single plane and biplane cine angiographic studies.