The mechanical behavior of a vibrating wire in superfluid3He-B in the ballistic limit

An experimental procedure is described for the characterization of the response of very small vibrating wires to liquid³He at temperatures down to 120 µK. The relative scales of the mean free path in the liquid and the radius of the wire play a significant role in the interpretation of the results. It is shown that the same ideas concerning the transition from hydrodynamic to ballistic behavior as the temperature is reduced can be applied both to saturated³He-⁴He solutions and to superfluid³He-B.     

Is leptin sensitivity the link between smoking cessation and weight gain?

We performed a case-control study to investigate the association of the poor metaboliser genotype of the cytochrome P450 2D6 gene with Parkinson's disease (PD). Genotyping was determined by the polymerase chain reaction followed by digestion with restriction enzymes. The poor metaboliser genotype was more frequent in 112 patients with PD than in 206 matched controls (odds ratio 1.7, 95% CI: 0.94-2.45). A meta-analysis of these results together with ten other published studies gave a pooled odds ratio for the poor metaboliser genotype of 1.47 (95% CI: 1.18-1.96, P=0.01). Thus, the poor metaboliser genotype has a small but highly significant association with PD which would be easily missed in small studies. Research now should focus on the mechanism of this association.     

The analysis of elastic-plastic adhesive stress in bonded lap joints in FRP structures

The majority of researchers who investigate the theoretical distribution of adhesive stresses in bonded lap joints assume that the adhesive behaves as a linear elastic material. While this assumption does provide useful information, for example, the intensities of stress concentrations and their locations, the results do not reflect the true stress distribution or behaviour at appreciable levels of loading. Practical joints using typical structural adhesives will incur considerable adhesive yielding as loading is increased to failure. The analysis must, therefore, include plastic yielding of the adhesive.This paper presents two analytical techniques, namely, the classical and finite element theories, which will be used to determine elastic-plastic adhesive stress distribution in bonded lap joints. The theoretical work will consider the single, double and tubular lap configurations having both similar and dissimilar adherends. Case studies will be presented to illustrate the development of adhesive yielding and to compare the different analytical techniques.The classical approach was found to be intractable to a closed form solution and consequently a numerical method was employed.