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101.
Hinkel Georg Goldschmidt Thomas Burger Erik Reussner Ralf 《Software and Systems Modeling》2019,18(1):129-155
Software and Systems Modeling - Model-driven engineering (MDE) has proved to be a useful approach to cope with today’s ever-growing complexity in the development of software systems;... 相似文献
102.
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104.
Computational Economics - We present a new modeling approach for house price movements as a consequence of the trading behavior of market agents. In our modeling approach, all agents are assumed to... 相似文献
105.
S. Herweg F. Huber S. Atamer R. Steiner R. Weller B. Sauer S. Wiesker M. Mármol Fernández 《Forschung im Ingenieurwesen》2018,82(4):273-283
As part of a cooperation project, Daimler AG and the Institute of Machine Elements, Gears, and Transmissions (MEGT) at the Technische Universität Kaiserslautern are carrying out detailed investigations on a valve train with roller lever. The aim of the project is to develop a detailed simulation method that allows the secondary movement of the valve train to be modeled and thus represents an extension of the classic valve train dynamics simulation. This opens up the opportunity to evaluate the processes within the valve train in detail in the early stages of the product development process. This report introduces the validation of the methodology based on experimental results. First, the focus is placed on the cam-roller contact, which induces the secondary movement of the valve train. This movement takes place in the axial direction of the camshaft so that the validation takes place on the basis of the measured force in this direction. The force is dependent on the load, i.?e. the combination of speed and normal force, as well as the angular misalignments between cam and roller. Following the validation of the detailed modeling of the cam-roller contact, the gained knowledge is transferred into the extended valve train simulations. Finally the valve train simulation is validated. 相似文献
106.
Dr. Aline Telzerow Dr. Juraj Paris Dr. Maria Håkansson Dr. Javier González-Sabín Dr. Nicolas Ríos-Lombardía Prof. Dr. Harald Gröger Dr. Francisco Morís Dr. Martin Schürmann Prof. Dr. Helmut Schwab Dr. Kerstin Steiner 《Chembiochem : a European journal of chemical biology》2021,22(7):1232-1242
Amine transaminases (ATAs) are used to synthesize enantiomerically pure amines, which are building blocks for pharmaceuticals and agrochemicals. R-selective ATAs belong to the fold type IV PLP-dependent enzymes, and different sequence-, structure- and substrate scope-based features have been identified in the past decade. However, our knowledge is still restricted due to the limited number of characterized (R)-ATAs, with additional bias towards fungal origin. We aimed to expand the toolbox of (R)-ATAs and contribute to the understanding of this enzyme subfamily. We identified and characterized four new (R)-ATAs. The ATA from Exophiala sideris contains a motif characteristic for d -ATAs, which was previously believed to be a disqualifying factor for (R)-ATA activity. The crystal structure of the ATA from Shinella is the first from a Gram-negative bacterium. The ATAs from Pseudonocardia acaciae and Tetrasphaera japonica are the first characterized (R)-ATAs with a shortened/missing N-terminal helix. The active-site charges vary significantly between the new and known ATAs, correlating with their diverging substrate scope. 相似文献
107.
Pietro Abate Roberto Di Cosmo Ralf Treinen Stefano Zacchiroli 《Journal of Systems and Software》2012,85(10):2228-2240
Maintenance of component-based software platforms often has to face rapid evolution of software components. Component dependencies, conflicts, and package managers with dependency solving capabilities are the key ingredients of prevalent software maintenance technologies that have been proposed to keep software installations synchronized with evolving component repositories. We review state-of-the-art package managers and their ability to keep up with evolution at the current growth rate of popular component-based platforms, and conclude that their dependency solving abilities are not up to the task.We show that the complexity of the underlying upgrade planning problem is NP-complete even for seemingly simple component models, and argue that the principal source of complexity lies in multiple available versions of components. We then discuss the need of expressive languages for user preferences, which makes the problem even more challenging.We propose to establish dependency solving as a separate concern from other upgrade aspects, and present CUDF as a formalism to describe upgrade scenarios. By analyzing the result of an international dependency solving competition, we provide evidence that the proposed approach is viable. 相似文献
108.
H. Steiner W. Hortschitz M. Stifter F. Keplinger T. Sauter 《Microsystem Technologies》2014,20(4-5):551-557
The thermal actuator presented in this paper consists of two symmetrically V-shaped beam stacks, where each stack consists of six beams in parallel. The stacks are coupled facing each other and slightly shifted along the mirror axis. Both stacks are connected to a lever beam and fixed at four anchor regions to the substrate. Due to the difference in the coefficient of thermal expansion of the material of the beams and the one of the substrate, the tip of the lever moves perpendicular to the mirror axis. The device is fabricated from galvanic deposited nickel on a silicon substrate. Finite element simulations were carried out to optimize the design with respect to the sensitivity and the maximum mechanical stress. The stress needs to be lower than the yield strength of the material. Otherwise, plastic deformations of the beams would lead to irreversible deflections of the beam tip. This limits the overall sensitivity of the design. First results of the device with 400 μm long bent beams show a linear behavior and a sensitivity of 0.5 μm/K and forces of 66 μN/K for a temperature range of ?30 °C up to +40 °C. 相似文献
109.
Photonic Nanostructures Patterned by Thermal Nanoimprint Directly into Organo‐Metal Halide Perovskites
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110.
Yanmin Zhou Adam Robinson Ullrich Steiner Walter Federle 《Journal of the Royal Society Interface》2014,11(98)
Insect climbing footpads are able to adhere to rough surfaces, but the details of this capability are still unclear. To overcome experimental limitations of randomly rough, opaque surfaces, we fabricated transparent test substrates containing square arrays of 1.4 µm diameter pillars, with variable height (0.5 and 1.4 µm) and spacing (from 3 to 22 µm). Smooth pads of cockroaches (Nauphoeta cinerea) made partial contact (limited to the tops of the structures) for the two densest arrays of tall pillars, but full contact (touching the substrate in between pillars) for larger spacings. The transition from partial to full contact was accompanied by a sharp increase in shear forces. Tests on hairy pads of dock beetles (Gastrophysa viridula) showed that setae adhered between pillars for larger spacings, but pads were equally unable to make full contact on the densest arrays. The beetles'' shear forces similarly decreased for denser arrays, but also for short pillars and with a more gradual transition. These observations can be explained by simple contact models derived for soft uniform materials (smooth pads) or thin flat plates (hairy-pad spatulae). Our results show that microstructured substrates are powerful tools to reveal adaptations of natural adhesives for rough surfaces. 相似文献