Thermal characteristics of a non-newtonian fluid in a porous thrust bearing

A study of the behavior of an externally pressurized circular porous thrust bearing using a non-newtonian fluid lubricant was made. The governing Navier-Stokes equations were reduced to a set of ordinary differential equations and were solved numerically with the cross-flow Reynolds number and the Prandtl number as parameters. The pressure distribution and the lift force were evaluated. The effects of cross-viscosity coefficients on the flow and heat transfer characteristics of the bearing were determined.     

Selection of optimum tool geometry and cutting conditions using a surface roughness prediction model for end milling

Influence of tool geometry on the quality of surface produced is well known and hence any attempt to assess the performance of end milling should include the tool geometry. In the present work, experimental studies have been conducted to see the effect of tool geometry (radial rake angle and nose radius) and cutting conditions (cutting speed and feed rate) on the machining performance during end milling of medium carbon steel. The first and second order mathematical models, in terms of machining parameters, were developed for surface roughness prediction using response surface methodology (RSM) on the basis of experimental results. The model selected for optimization has been validated with the Chi square test. The significance of these parameters on surface roughness has been established with analysis of variance. An attempt has also been made to optimize the surface roughness prediction model using genetic algorithms (GA). The GA program gives minimum values of surface roughness and their respective optimal conditions.     

Toxicological effects of beryllium on platelets and vascular endothelium

The crystal structure of rabbit muscle pyruvate kinase complexed with Mn2+, K+, and pyruvate revealed a binding site of K+ [T. M. Larsen, L. T. Laughlin, H. M. Holden, I. Rayment, and G. H. Reed (1994) Biochemistry 33, 6301-6309]. Sequence comparisons of rabbit muscle pyruvate kinase and pyruvate kinases from Corynebacterium glutamicum and Escherichia coli, which do not exhibit a requirement for activation by monovalent cations, indicate that the only substitutions in the K+ binding site are conservative. Glu 117 in the rabbit muscle enzyme, which is close to the K+ site, is, however, replaced by Lys in these two bacterial pyruvate kinases. The proximity of Glu 117 to K+ in the structure of the rabbit enzyme and conservation of the binding site in the bacterial enzymes which lack a dependence on monovalent cations suggested that a protonated epsilon-amino group of Lys 117 in these bacterial enzymes may provide an "internal monovalent cation." Site-specific mutant forms of the rabbit enzyme corresponding to E117K, E117A, E117D, and E117K/K114Q pyruvate kinase were examined to test this hypothesis. The E117K pyruvate kinase exhibits 12% of the activity of the fully activated wild-type enzyme but is > 200-fold more active than the wild-type enzyme in the absence of activating monovalent cations. Moreover, the activity of E117K pyruvate kinase exhibits no stimulation by monovalent cations in the assay mixtures. Both E117A and E117D pyruvate kinases retain activation by monovalent cations but have reduced activities relative to wild type. The results are consistent with the hypothesis that pyruvate kinases that do not require activation by monovalent cations supply an internal monovalent cation in the form of a protonated epsilon-amino group of Lys. The results also support the assignment of the monovalent cation in the active site of pyruvate kinase.     

Recent advances in the treatment of Hodgkin's disease

Most patients who present with Hodgkin's disease today can be cured of their disease. Current treatments strive to maintain a high level of efficacy while reducing side effects that limit the quality and length of survival. Sophisticated molecular techniques continue to aid our understanding of the etiology and pathogenesis of this disease. However, the heterogeneity and paucity of "malignant" cells in Hodgkin's disease continue to limit our ability to articulate a coherent and encompassing model.     

Humidity Sustained Wearable Pouch‐Type Triboelectric Nanogenerator for Harvesting Mechanical Energy from Human Activities

Triboelectric nanogenerators (TENGs) are gaining much research interest recently owing to their facile and cost‐effective device structure. However, the effect of relative humidity (in moisture atmosphere) on the output performance still needs to be resolved. Herein, a pouch‐type TENG is proposed to significantly reduce the effect of relative humidity on its electrical output and a stable performance is also attained in a humid environment. In this regard, a dielectric and dielectric materials‐based TENG (DD‐TENG) is first developed using nanoarchitecture polydimethylsiloxane (NA‐PDMS) and multiwalled carbon nanotube/nylon composite layers as a triboelectric material with the negative and positive tendencies, respectively. The NA‐PDMS and nylon composite layers play a key role in increasing the surface contact area and surface charge density between the dielectric/triboelectric materials as well as the output performance of DD‐TENG. However, the DD‐TENG device exhibits a stable and high output performance with the effective output power density of ≈25.35 W m^?2. Additionally, the performance of the pouch‐type DD‐TENG device is not almost affected even though the relative humidity is increased from 35 to 81%, while it is dramatically decreased for the nonpouch‐type device. Finally, the pouch‐type DD‐TENG is employed as a wearable device to effectively harvest the mechanical energy from daily human activities.     

M-Curves path planning model for mobile anchor node and localization of sensor nodes using Dolphin Swarm Algorithm

Wireless Networks - Location information of a sensor node is the primary concern to process the sensed data in Wireless Sensor Networks (WSNs). The location of the sensor node is used in other...     

Assessing two large area burnt area products across Australian Southern Forests

Burnt area is a critical parameter for estimating emissions of greenhouse gases associated with biomass burning. Several burnt area products (BAPs) derived from Earth Observation satellites/sensors have been released; these are based on different spatial resolutions and derived using different methodologies so that accuracies can vary amongst them. This study validates a global (MODIS) and a national (AVHRR) BAP across Australian southern forests using two reference datasets: state fire histories (SFHs) from 2000 to 2013 and a forest cover map derived through high resolution air photo interpretation (API). The spatial and temporal agreement between fires in the BAPs and reference SFH were analysed based on 2610 sample points representative of Australian southern forest types (successful detection was evaluated according to fire type: planned burn vs. wildfire, size of fire, and land tenure). Results show that both BAPs were most successful when identifying large wildfires (>5000 ha). Overall accuracy for AVHRR and MODIS was 73.9% and 62.5%, respectively. When compared to the API derived forest cover map as reference dataset, both products achieved higher overall accuracies (94.1% for AVHRR and 87.1% for MODIS); an expected result given that the fires detected in this dataset are known to be observable using Earth observation data. But regardless of reference dataset, the AVHRR BAP which is tailored to Australian conditions achieved better results than the MODIS global BAP. Also, the AVHRR archive in Australia goes back to 1988, which is an important consideration for calculating wildfire history for greenhouse gas accounting.     

An n-sided polygonal finite element for nonlocal nonlinear analysis of plates and laminates

In this study, a locking-free n-sided C¹ polygonal finite element is presented for nonlinear analysis of laminated plates. The plate kinematics is based on Reddy's third-order shear deformation theory (TSDT). The in-plane displacements are approximated using barycentric form of Lagrange shape functions. The weak-form Galerkin formulation based on the kinematics of TSDT requires the C¹ approximation of the transverse displacement over the polygonal element. This is achieved by embedding the C⁰ Lagrange interpolants over a cubic Bernstein-Bezier patch defined over the n-sided polygonal element. Such an approach ensures the continuity of the derivative field at the inter-element edges. In addition, Eringen's stress-gradient nonlocal constitutive equations are used in the present formulation to account for nonlocality. The effect of geometric nonlinearity is taken by considering the von Kármán geometric nonlinearity. Examples are presented to show the effect of nonlocality, geometric nonlinearity, and the lamination scheme on the bending behavior of laminated composite plates. The results are compared with analytical solutions, conventional FEM results, and with those available in the literature. Shear locking is addressed considering reduced integration and consistent interpolation techniques. The patch test is used to check the convergence of the element developed.     

Dry Etching with Nanoparticles: Formation of High Aspect‐Ratio Pores and Channels Using Magnetic Gold Nanoclusters

Methods for generating nanopores in substrates typically involve one or more wet‐etching steps. Here a fundamentally different approach to produce nanopores in sheet substrates under dry, ambient conditions, using nanosecond‐pulsed laser irradiation and magnetic gold nanoclusters (MGNCs) as the etching agents is described. Thermoplastic films (50–75 µm thickness) are coated with MGNCs then exposed to laser pulses with a coaxial magnetic field gradient, resulting in high‐aspect ratio channels with tapered cross sections as characterized by confocal fluorescence tomography. The dry‐etching process is applicable to a wide variety of substrates ranging from fluoropolymers to borosilicate glass, with etch rates in excess of 1 µm s^–1. Finite‐element modeling suggests that the absorption of laser pulses by MGNCs can produce temperature spikes of nearly 1000 °C, which is sufficient for generating photoacoustic responses that can drive particles into the medium, guided by magnetomotive force.