Multicast support for mobile hosts using Mobile IP: Design issues and proposed architecture

In this paper, we consider the problem of providing multicast to mobile hosts using Mobile IP for network routing support. Providing multicast in an internetwork with mobile hosts is made difficult because many multicast protocols are inefficient when faced with frequent membership or location changes. This basic difficulty can be handled in a number of ways, but three main problems emerge with most solutions. The tunnel convergence problem, the duplication problem, and the scoping problem are identified in this paper and a set of solutions are proposed. The paper describes an architecture to support IP multicast for mobile hosts using Mobile IP. The basic unicast routing capability of Mobile IP is used to serve as the foundation for the design of a multicast service facility for mobile hosts. We believe that our scheme is transparent to higher layers, simple, flexible, robust, scalable, and, to the extent possible, independent of the underlying multicast routing facility. For example, our scheme could interoperate with DVMRP, MOSPF, CBT, or PIM in the current Internet. Where differences exist between the current version of IP (IPv4) and the next generation protocol (IPv6), these differences and any further optimizations are discussed. This revised version was published online in June 2006 with corrections to the Cover Date.     

Human aging and duration judgments: A meta-analytic review.

Differences in duration judgments made by younger and older adults were reviewed. Previous research is unclear about whether such differences exist and, if so, how they may be explained. The meta-analyses revealed substantial age-related differences. Older adults gave larger verbal estimates and made shorter productions of duration than did younger adults. There were no age-related differences in reproduction of duration or in psychophysical slope relating judged and target duration. Older adults' duration estimates were more variable than were those of younger ones. Findings are discussed in terms of pacemaker rate and attentional resources. An explanation regarding divided attention between nontemporal and temporal information processing best explains the findings. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Toward a conceptual model of organizational regression.

This article presents an elaborated model of organizational regression suggesting that, within the framework of general systems and catastrophe theory, organizational units and whole enterprises can be viewed as struggling to attain a state of super-resilience that enables them to cope effectively with a large number of regressive forces. The model comprises 6 phases of organizational regression that occur either in a 10-stage process or in a chaotically unpredictable but behaviorally understandable and orderly sequence. Internal and external regressive forces that constantly pressure an organization toward less effective performance and more primitive behavior are identified. Organizational barriers and balancing forces that counter the regressive pressures are also described, along with the consequences of regression for individuals and enterprises. Several brief case illustrations (e.g., Montgomery Ward, Apple Computer, and General Electric Corporation) are provided to highlight aspects of this conceptual approach. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Frameworks: the future of formal software development?

It could be argued that the primary issue to be dealt with in software engineering today is re-use of software. Current software development rarely, if ever, starts from nothing. Unfortunately, the same cannot be said for the development of specifications. To overcome this problem, various works have attempted to show how specifications can be built using architectural principles. We discuss one such approach in particular, the Architectural Semantics of Open Distributed Processing. We show the limitations of this work with regard to the architecting of specifications and propose a new approach, based on frameworks. To highlight the approach we use the work currently being done in the TOSCA project in its development of a service creation and validation environment for telecommunication services.     

Reactivity to novelty in cognitively-impaired and cognitively-unimpaired aged rats and young rats

Two distinct populations of aged, Long-Evans rats can be identified on the basis of performance in the Morris water maze task. Aged (24 month) unimpaired rats perform similarly to young (six month) animals. Aged, impaired rats display latencies to find the submerged platform greater than two standard deviations from the mean of the young animals. A hallmark of efficient cognitive processing is the ability to cope with environmental change. Consequently, the present studies were conducted to assess if aged, impaired animals display differential reactivity to repeated exposure to novel stimuli. Reactivity was assessed by examining the degree of (i) consumption of a novel gustatory/olfactory stimulus (sweetened milk), (ii) pain inhibition induced by exposure to a novel hot-plate (48.5 degrees C) apparatus and (iii) exploratory behaviour in an elevated plus maze and a novel open field. Aged, impaired rats exhibited lower milk consumption on day one and protracted reactivity (lower consumption over days two to eight) in comparison to aged, unimpaired and young animals. Aged, impaired rats were more reactive to novelty on the hot plate test (as indicated by longer paw lick latencies); this novelty-induced pain inhibition did not habituate in aged, impaired rats following repeated plate exposures. The degree of exploratory behaviour in both the plus maze and the open field was reduced in aged, impaired rats. This effect was not entirely a consequence of deficient affective mechanisms, as measures of anxiety (e.g., time in open arms, time in inner squares) were not different among aged impaired, aged unimpaired and young animals. These results are the first to demonstrate that behavioural deficits observed in aged, impaired animals extend beyond the impairments observed in the water maze. This behavioural profile is attributed, in part, to heightened anxiety. In addition, the impairments observed in aged, impaired animals may also reflect a reduced sensitivity to the positive incentive properties of novel stimuli.     

Genotype-phenotype analysis in four families with mutations in beta-myosin heavy chain gene responsible for familial hypertrophic cardiomyopathy

The effects of two progestogen-only pills containing either 75 microgram desogestrel (DSG) or 30 microgram levonorgestrel (LNG) on hemostasis were investigated in a double-blind, randomized, controlled study of seven treatment cycles in 78 healthy women. DSG reduced factor VII activity (p < 0.05) and prothrombin fragment 1+2 (p < 0.05) and increased protein S (p < 0.001). LNG reduced factor VII activity (p < 0.01) and plasminogen activity (p < 0.01) and increased tissue-plasminogen activator (t-PA) (p < 0.05). At the end of the post-treatment cycle with DSG, protein S (p < 0.01) and t-PA (p < 0.05) were increased and plasminogen activity was decreased (p < 0.05), whereas with LNG, t-PA was increased (p < 0.001) and prothrombin fragment 1+2 (p < 0.05) and plasminogen activity (p < 0.001) were decreased. Between-group comparisons revealed higher values for DSG regarding the anticoagulatory parameter protein S at cycle 7 (p < 0.01) and post-treatment assessments (p < 0.05), and the fibrinolytic parameter plasmin-antiplasmin complex was higher with DSG at cycle 7 (p < 0.05) and at post-treatment (p < 0.05). Both preparations had comparable and potentially favorable effects of hemostasis, and may offer suitable hormonal contraception to women with a personal or family history of venous thromboembolic diseases.     

Comparisons of highly virulent H5N1 influenza A viruses isolated from humans and chickens from Hong Kong

Genes of an influenza A (H5N1) virus from a human in Hong Kong isolated in May 1997 were sequenced and found to be all avian-like (K. Subbarao et al., Science 279:393-395, 1998). Gene sequences of this human isolate were compared to those of a highly pathogenic chicken H5N1 influenza virus isolated from Hong Kong in April 1997. Sequence comparisons of all eight RNA segments from the two viruses show greater than 99% sequence identity between them. However, neither isolate's gene sequence was closely (>95% sequence identity) related to any other gene sequences found in the GenBank database. Phylogenetic analysis demonstrated that the nucleotide sequences of at least four of the eight RNA segments clustered with Eurasian origin avian influenza viruses. The hemagglutinin gene phylogenetic analysis also included the sequences from an additional three human and two chicken H5N1 virus isolates from Hong Kong, and the isolates separated into two closely related groups. However, no single amino acid change separated the chicken origin and human origin isolates, but they all contained multiple basic amino acids at the hemagglutinin cleavage site, which is associated with a highly pathogenic phenotype in poultry. In experimental intravenous inoculation studies with chickens, all seven viruses were highly pathogenic, killing most birds within 24 h. All infected chickens had virtually identical pathologic lesions, including moderate to severe diffuse edema and interstitial pneumonitis. Viral nucleoprotein was most frequently demonstrated in vascular endothelium, macrophages, heterophils, and cardiac myocytes. Asphyxiation from pulmonary edema and generalized cardiovascular collapse were the most likely pathogenic mechanisms responsible for illness and death. In summary, a small number of changes in hemagglutinin gene sequences defined two closely related subgroups, with both subgroups having human and chicken members, among the seven viruses examined from Hong Kong, and all seven viruses were highly pathogenic in chickens and caused similar lesions in experimental inoculations.     

Occupational burnout, tolerance for stress, and coping among nurses in rehabilitation units.

The relation of problem-solving confidence, perceived tolerance of stressors, and situation-specific coping efforts to occupational burnout was examined among 88 nurses in physical rehabilitation units. Participants completed measures of problem solving and burnout, and were administered a questionnaire that required them to list stressors encountered at work and their ability to tolerate this stressor. Participants were also asked to list their typical ways of coping with this stressor. Consistent with predictions, confidence in one's ability to handle problems and perceived tolerance were significantly predictive of lower burnout scores, regardless of time spent on the job. Of the coping variables, emotion-focused coping was significantly associated with higher burnout scores. Post-hoc analyses of self-reported coping activities indicated that some coping efforts (e.g., taking time off from work, confronting a supervisor) could be construed as symptoms of burnout, according to theoretical conceptualizations. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Processes of causal explanation and dispositional attribution.

Causal explanation and dispositional attribution are distinguished. Causal explanation involves giving an explanation for why a particular event occurred, whereas dispositional attribution involves learning about the characteristics of some entity. Moreover, it is proposed that production of causal explanations requires J. S. Mill's (1872/1973) method of difference, whereas production of dispositional attributions requires Mill's method of agreement. Exp 1 shows that both the method of difference and the method of agreement are used to make causal explanations. Experiments 1, 2, and 3 indicate that lay attributors consistently favor use of the method of agreement but not the method of difference to make dispositional attributions of both faciliatory and inhibitory characteristics. The distinction between causal explanation and dispositional attribution is used to organize seemingly contradictory findings and to provide an integrative framework for models of causal judgment. (PsycINFO Database Record (c) 2010 APA, all rights reserved)