Analytical study of binary differential impulse radio-ultra wide band over single-mode fibre systems using two receiver structures

A binary differential impulse radio-ultra wide band (IR-UWB) communication scheme over a singlemode optical fibre is examined. For a receiver structure, the conventional electrical receiver as well as an optical receiver structure, which is similar to the optical receiver used for digital, optically phase-modulated differential phase shift keying, are considered. The optical receiver can alleviate the IR-UWB receiver implementation challenges and it is studied for the first time in the context of IR-UWB. Considering various important noises, for example, phase noise, laser intensity noise, thermal noise and shot noise, analytical expressions for the error probability of the aforementioned receivers are derived. The mathematical models for optical components including laser diode and single-mode fibre, along with the analytical expressions for the receiver?s error probability, are used to evaluate the overall performance of an UWB communication system over a fibre transmission medium. Furthermore, the electrical receiver is compared with the optical receiver and it is shown that the performance of the optical receiver can be as good as that of the electrical receiver and even better. The impact of wireless channel fading, bias current of laser diode and the coherence time of laser diode on the UWB over fibre system performance is also examined.     

Investigating preparation and characterisation of diphtheria toxoid‐loaded on sodium alginate nanoparticles

This paper aims to investigate the preparation and characterisation of the alginate nanoparticles (NPs) as antigen delivery system loaded by diphtheria toxoid (DT). For this purpose, both the loading capacity (LC) and Loading efficiency (LE) of the alginate NPs burdened by DT are evaluated. Moreover, the effects of different concentrations of sodium alginate and calcium chloride on the NPs physicochemical characteristics are surveyed in addition to other physical conditions such as homogenization time and rate. To do so, the NPs are characterised using particle size and distribution, zeta potential, scanning electron microscopy, encapsulation efficiency, in vitro release study and FT‐IR spectroscopy. Subsequently, the effects of homogenization time and rate on the NPs are assessed. At the meantime, the NPs LC and efficiency in several DT concentrations are estimated. The average size of the NPs was 400.7 and 276.6 nm for unloaded and DT loaded, respectively. According to the obtained results, the zeta potential of the blank and DT loaded NPs are estimated as −23.7 mV and −21.2 mV, respectively. Whereas, the LC and LE were >80% and >90%, in that order. Furthermore, 95% of the releasing DT loaded NPs occurs at 140 h in the sustained mode without any bursting release. It can be concluded that the features of NPs such as morphology and particle size are strongly depended on the calcium chloride, sodium alginate concentrations and physicochemical conditions in the NPs formation process. In addition, appropriate concentrations of the sodium alginate and calcium ions would lead to obtaining the desirable NPs formation associated with the advantageous LE, LC (over 80%) and sustained in vitro release profile. Ultimately, the proposed NPs can be employed in vaccine formulation for the targeted delivery, controlled and slow antigen release associated with the improved antigen stability.     

Accurate crop-type classification using multi-temporal optical and multi-polarization SAR data in an object-based image analysis framework

Accurate crop-type classification is a challenging task due, primarily, to the high within-class spectral variations of individual crops during the growing season (phenological development) and, second, to the high between-class spectral similarity of crop types. Utilizing within-season multi-temporal optical and multi-polarization synthetic aperture radar (SAR) data, this study introduces a combined object- and pixel-based image classification methodology for accurate crop-type classification. Particularly, the study investigates the improvement of crop-type classification by using the least number of multi-temporal RapidEye (RE) images and multi-polarization Radarsat-2 (RS-2) data utilized in an object- and pixel-based image analysis framework. The method was tested on a study area in Manitoba, Canada, using three different classifiers including the standard Maximum Likelihood (ML), Decision Tree (DT), and Random Forest (RF) classifiers. Using only two RE images of July and August, the proposed method results in overall accuracies (OAs) of about 95%, 78%, and 93% for the ML, DT, and RF classifiers, respectively. Moreover, the use of only two quad-pol images of RS-2 of June and September resulted in OAs of 92%, 75%, and 90% for the ML, DT, and RF classifiers, respectively. The best classification results were achieved by the synergistic use of two RE and two RS-2 images. In this case, the overall classification accuracies were 97% for both ML and RF classifiers. In addition, the average producer’s accuracies of 95% and 96% were achieved by the ML and RF classifiers, respectively, whereas the average user accuracy was 94% for both classifiers. The results indicated promising potentials for rapid and cost-effective local-scale crop-type classification using a limited number of high-resolution optical and multi-polarization SAR images. Very accurate classification results can be considered as a replacement for sampling the agricultural fields at the local scale. The result of this very accurate classification at discrete locations (approximately 25 × 25 km frames) can be applied in a separate procedure to increase the accuracy of crop area estimation at the regional to provincial scale by linking these local very accurate spatially discrete results to national wall-to-wall continuous crop classification maps.     

Glucosamine conjugated iron oxide and graphene oxide nanohybrid for smart drug delivery

Smart drug delivery systems have attracted a lot of attention as one of the new treatment methods for cancer. In this study, a smart drug delivery system carrying anticancer drugs was obtained by the intelligent synthesis of glucosamine (GA)-functionalized graphene oxide (GO)-based iron oxide nanoparticles (Fe₃O₄@GO-GA) using Hummers and chemical co-precipitation processes. Nanohybrids have a high surface area (280.26 m²/g) and superparamagnetic behaviour (Ms = 26.017 emu/g), indicating a significant loading capacity (373.78 mg/mg) and efficiency (96.3%) for pharmaceutical loading. An adsorption study of conventional daunorubicin (DNR) on this carrier showed that the drug release is more prone to occur under acidic conditions (pH = 5.5), at moderately high temperatures (T = 40°C), and in the absence of smart carriers. The toxicity of the smart nanohybrids was examined using the sulphorhodamine B (SRB) assay in Michigan Cancer Foundation-7 (MCF-7) cell lines. The rate of death of cells exposed to smart drug-containing systems in comparison to the systems without GA shows that GA reduces the toxicity of Fe₃O₄@GO.     

High Ionic Conductivity Motivated by Multiple Ion-Transport Channels in 2D MOF-Based Lithium Solid State Battery

Metal-organic frameworks (MOFs) have been proposed as novel fillers for constructing polymer solid electrolytes based composite electrolytes. However, MOFs are generally used as passive fillers, in-depth revealing the binding mode between MOFs and polyethylene oxide (PEO), the critical role of MOFs in facilitating Li⁺ transport in solid electrolytes is full of challenges. Herein, inspired by density functional theory (DFT) the 2D-MOF with rich unsaturated metal coordination sites that can bind the O atom in PEO through the metal–oxygen bond,  anchor TFSI⁻ to release Li⁺, resulting in a remarkable Li⁺ transference number of 0.58, is reported according well with the experimental results and molecular dynamics (MD) simulation. Impressively, after the introduction of the 2D-MOF, the Li⁺ can rapidly hop along the benzene ring center within the 2D-MOF plane, and the interface between the benzene ring and PEO can also serve as a fast Li⁺ migration pathway, delivering multiple ion-transport channels, which present a high ion conductivity of 4.6 × 10⁻⁵ S cm⁻¹ (25 °C). The lithium symmetric battery is stable for 1300 h at 60 °C, 0.1 mA cm⁻². The assembled lithium metal solid state battery maintains high capacity of 162.8 mAh g⁻¹ after 500 cycles at 60 °C and 0.5 C. This multiple ion-transport channels approach brings new ideas for designing advanced solid electrolytes.     

Improved Cytotoxicity and Induced Apoptosis in HeLa Cells by Co-loading Vitamin E Succinate and Curcumin in Nano-MIL-88B-NH2

One of the strategies for improved therapeutic effects in cancer therapy is combination chemotherapy. In this study, a flexible nano-MOF (Fe-MIL-88B-NH₂) was synthesized in a sonochemical process, then co-loaded with α-tocopheryl succinate (TOS) and curcumin (CCM). The anticancer activity of co-loaded Fe-MIL-88B-NH₂ (Fe-MIL-88B-NH₂/TOS@CCM) against the HeLa cells was compared with that of the single-loaded counterpart (Fe-MIL-88B-NH₂@CCM). MTT analysis indicates improved cytotoxicity of Fe-MIL-88B-NH₂/TOS@CCM. The data from the cell apoptosis assay indicated more apoptosis in the case of the co-loaded nano-MOF. This study indicates the positive effect of the presence of TOS on enhancing the anticancer effect of Fe-MIL-88B-NH₂@CCM to prepare a more efficient drug delivery nanosystem.     

Trapping Lithium Selenides with Evolving Heterogeneous Interfaces for High-Power Lithium-Ion Capacitors

Transition metal selenides anodes with fast reaction kinetics and high theoretical specific capacity are expected to solve mismatched kinetics between cathode and anode in Li-ion capacitors. However, transition metal selenides face great challenges in the dissolution and shuttle problem of lithium selenides, which is the same as Li-Se batteries. Herein, inspired by the density functional theory calculations, heterogeneous can enhance the adsorption of Li₂Se relative to single component selenide electrodes, thus inhibiting the dissolution and shuttle effect of Li₂Se. A heterostructure material (denoted as CoSe₂/SnSe) with the ability to evolve continuously (CoSe₂/SnSe→Co/Sn→Co/Li₁₃Sn₅) is successfully designed by employing CoSnO₃-MOF as a precursor. Impressively, CoSe₂/SnSe heterostructure material delivers the ultrahigh reversible specific capacity of 510 mAh g⁻¹ after 1000 cycles at the high current density of 4 A g⁻¹. In situ XRD reveals the continuous evolution of the interface based on the transformation and alloying reactions during the charging and discharging process. Visualizations of in situ disassembly experiments demonstrate that the continuously evolving interface inhibits the shuttle of Li₂Se. This research proposes an innovative approach to inhibit the dissolution and shuttling of discharge intermediates (Li₂Se) of metal selenides, which is expected to be applied to metal sulfides or Li-Se and Li-S energy storage systems.