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排序方式: 共有237条查询结果,搜索用时 15 毫秒
41.
Ming-Yu Li Yusuke Hirono Sabina D Koukourinkova Mao Sui Sangmin Song Eun-Soo Kim Jihoon Lee Gregory J Salamo 《Nanoscale research letters》2012,7(1):550
In this paper, the formation of Ga droplets on photo-lithographically patterned GaAs (100) and the control of the size and density of Ga droplets by droplet epitaxy using molecular beam epitaxy are demonstrated. In extension of our previous result from the journal Physical Status Solidi A, volume 209 in 2012, the sharp contrast of the size and density of Ga droplets is clearly observed by high-resolution scanning electron microscope, atomic force microscope, and energy dispersive X-ray spectrometry. Also, additional monolayer (ML) coverage is added to strength the result. The density of droplets is an order of magnitude higher on the trench area (etched area), while the size of droplets is much larger on the strip top area (un-etched area). A systematic variation of ML coverage results in an establishment of the control of size and density of Ga droplets. The cross-sectional line profile analysis and root mean square roughness analysis show that the trench area (etched area) is approximately six times rougher. The atomic surface roughness is suggested to be the main cause of the sharp contrast of the size and density of Ga droplets and is discussed in terms of surface diffusion. 相似文献
42.
Magdalen Zlatanov Ginka Antova Maria Angelova-Romova Svetlana Momchilova Sabina Taneva Boryana Nikolova-Damyanova 《Journal of the American Oil Chemists' Society》2012,89(8):1393-1401
The lipid composition of the seed oil of three varieties (L-74, VIR-11 and BGR-455) of Lallemantia iberica Fisch. &; Mey. (Lamiaceae) harvested in Bulgaria was examined in detail. Triacylglycerols (TAG >90%), phospholipids (<3%), sterol esters (~0.2%), and accompanying compounds—sterols (~0.3%) and tocopherols (336–499 mg/kg)—were determined for the first time. In addition, the specific distribution of fatty acids between the lipid classes was elucidated. Nineteen TAG species were unambiguously identified and quantified and of these the highly unsaturated trilinolenin, dilinolenyl linoleate and dilinolenyl palmitate comprised 59% of the total TAG. Phosphatidylcholine, phosphatidylinositol and phosphatidylethanolamine were the main phospholipids. Beta-sitosterol was the main sterol component, followed by campesterol and stigmasterol. Gamma-tocopherol predominated (>90%) in the tocopherol fraction. Palmitic acid (16:0) was the major fatty acid of the phospholipids and oleic acid (cis 9-18:1) dominated in the sterol ester fraction. The three varieties have similar lipid compositions with BGR-455 being slightly more saturated. Due to its composition, Lallemantia oil might compete successfully with flax and other plant oils as a source of linolenic fatty acid in industrial and dietary applications. 相似文献
43.
Cui En-Ji Song Na-Young Shrestha Sabina Chung In-Sik Kim Ji-Young Jeong Tae-Sook Baek Nam-In 《Food science and biotechnology》2012,21(2):619-624
Six flavonoid glycosides were isolated from the n-butanol fraction of cowpea seeds (Vigna sinensis K.) through silica gel (SiO2) and octadecyl silica gel (ODS) column chromatographies. Based on their chemical structures determined via interpretation
of spectroscopic data including NMR, MS, and IR, the compounds were identified as kaempferol 3-O-β-d-sophoroside (1), quercetin 3-O-β-d-sophoroside (2), isoquercitrin (3), hyperin (4), catechin 7-O-β-d-glucopyranoside (5), and quercetin 3-O-β-Dglucopyranosyl( 1→6)-O-β-d-galactopyranoside (6). This is the first report of the isolation of these flavonoids from this plant. Among these flavonoids, compound 2, 5, and 6 significantly inhibited LDL oxidation exhibiting 96.0±0.1 (IC50: 3.9 μM), 96.8±1.7 (IC50: 2.9 μM), and 97.4±0.1% (IC50: 3.5 μM) inhibition, respectively, at a concentration of 40 μM. 相似文献
44.
?ehaji?-Clancy Sabina; Effron Daniel A.; Halperin Eran; Liberman Varda; Ross Lee D. 《Canadian Metallurgical Quarterly》2011,101(2):256
Three studies, 2 conducted in Israel and 1 conducted in Bosnia and Herzegovina, demonstrated that affirming a positive aspect of the self can increase one's willingness to acknowledge in-group responsibility for wrongdoing against others, express feelings of group-based guilt, and consequently provide greater support for reparation policies. By contrast, affirming one's group, although similarly boosting feelings of pride, failed to increase willingness to acknowledge and redress in-group wrongdoing. Studies 2 and 3 demonstrated the mediating role of group-based guilt. That is, increased acknowledgment of in-group responsibility for out-group victimization produced increased feelings of guilt, which in turn increased support for reparation policies to the victimized group. Theoretical and applied implications are discussed. (PsycINFO Database Record (c) 2011 APA, all rights reserved) 相似文献
45.
Sabina Nielsen 《Management International Review》2010,50(2):185-206
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This paper develops a multi-dimensional construct of top management team (TMT) internationalization reflecting TMT ability
to deal with challenges of managing firm foreign operations in the process of ongoing globalization. 相似文献
46.
47.
Dr. Sabina Yasmin Dr. Carmen Cerchia Dr. Vishnu Nayak Badavath Dr. Antonio Laghezza Prof. Fabrizio Dal Piaz Dr. Susanta K. Mondal Dr. Özlem Atlı Dr. Merve Baysal Dr. Sankaran Vadivelan Dr. S. Shankar Dr. Mohd Usman Mohd Siddique Dr. Ashok Kumar Pattnaik Dr. Ravi Pratap Singh Prof. Fulvio Loiodice Dr. Venkatesan Jayaprakash Prof. Antonio Lavecchia 《ChemMedChem》2021,16(3):484-498
Insulin resistance is a major pathophysiological feature in the development of type 2 diabetes (T2DM). Ferulic acid is known for attenuating the insulin resistance and reducing the blood glucose in T2DM rats. In this work, we designed and synthesized a library of new ferulic acid amides (FAA), which could be considered as ring opening derivatives of the antidiabetic PPARγ agonists Thiazolidinediones (TZDs). However, since these compounds displayed weak PPAR transactivation capacity, we employed a proteomics approach to unravel their molecular target(s) and identified the peroxiredoxin 1 (PRDX1) as a direct binding target of FAAs. Interestingly, PRDX1, a protein with antioxidant and chaperone activity, has been implied in the development of T2DM by inducing hepatic insulin resistance. SPR, mass spectrometry-based studies, docking experiments and in vitro inhibition assay confirmed that compounds VIe and VIf bound PRDX1 and induced a dose-dependent inhibition. Furthermore, VIe and VIf significantly improved hyperglycemia and hyperlipidemia in streptozotocin-nicotinamide (STZ-NA)-induced diabetic rats as confirmed by histopathological examinations. These results provide guidance for developing the current FAAs as new potential antidiabetic agents. 相似文献
48.
Machine Learning - In mobile health (mHealth) smart devices deliver behavioral treatments repeatedly over time to a user with the goal of helping the user adopt and maintain healthy behaviors.... 相似文献
49.
Srinu Tumpara Elena Korenbaum Mark Kühnel Danny Jonigk Beata Olejnicka Michael Davids Tobias Welte Beatriz Martinez-Delgado Sabina Janciauskiene 《International journal of molecular sciences》2021,22(4)
The C-terminal-fragments of alpha1-antitrypsin (AAT) have been identified and their diverse biological roles have been reported in vitro and in vivo. These findings prompted us to develop a monoclonal antibody that specifically recognizes C-36 peptide (corresponding to residues 359–394) resulting from the protease-associated cleavage of AAT. The C-36-targeting mouse monoclonal Immunoglobulin M (IgM) antibody (containing κ light chains, clone C42) was generated and enzyme-linked immunosorbent assay (ELISA)-tested by Davids Biotechnologie GmbH, Germany. Here, we addressed the effectiveness of the novel C42 antibody in different immunoassay formats, such as dot- and Western blotting, confocal laser microscopy, and flow cytometry. According to the dot-blot results, our novel C42 antibody detects the C-36 peptide at a range of 0.1–0.05 µg and shows no cross-reactivity with native, polymerized, or oxidized forms of full-length AAT, the AAT-elastase complex mixture, as well as with shorter C-terminal fragments of AAT. However, the C42 antibody does not detect denatured peptide in SDS-PAGE/Western blotting assays. On the other hand, our C42 antibody, unconjugated as well as conjugated to DyLight488 fluorophore, when applied for immunofluorescence microscopy and flow cytometry assays, specifically detected the C-36 peptide in human blood cells. Altogether, we demonstrate that our novel C42 antibody successfully recognizes the C-36 peptide of AAT in a number of immunoassays and has potential to become an important tool in AAT-related studies. 相似文献
50.
Jos Antonio Lpez-Guerrero Ins Ripa Sabina Andreu Raquel Bello-Morales 《International journal of molecular sciences》2020,21(23)
It is being increasingly demonstrated that extracellular vesicles (EVs) are deeply involved in the physiology of the central nervous system (CNS). Processes such as synaptic activity, neuron-glia communication, myelination and immune response are modulated by EVs. Likewise, these vesicles may participate in many pathological processes, both as triggers of disease or, on the contrary, as mechanisms of repair. EVs play relevant roles in neurodegenerative disorders such as Alzheimer’s or Parkinson’s diseases, in viral infections of the CNS and in demyelinating pathologies such as multiple sclerosis (MS). This review describes the involvement of these membrane vesicles in major demyelinating diseases, including MS, neuromyelitis optica, progressive multifocal leukoencephalopathy and demyelination associated to herpesviruses. 相似文献
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