Smoking behaviour and attitudes among adult Saudi nationals in Riyadh City, Saudi Arabia

OBJECTIVE: To measure the smoking behaviour and attitudes among Saudi adults residing in Riyadh City, the capital of the Kingdom of Saudi Arabia. DESIGN: Cross-sectional survey. SETTING AND SUBJECTS: Primary health care centres (PHCCs) in Riyadh City were selected by stratified random sampling. Subjects resident in each PHCC catchment area were selected by systematic sampling from their records in the PHCCs; 1534 adults aged 15 years and older were interviewed during January to April 1994. MAIN OUTCOME MEASURES: Self-reported smoking prevalence; age of smoking initiation; daily cigarette consumption; duration of smoking; reasons for smoking, not smoking, and quitting smoking; intentions to smoke in the future; and attitudes toward various tobacco control measures. RESULTS: 25.3% of respondents were current smokers, 10.2% were ex-smokers, and 64.5% had never smoked. About 79% of all smokers started smoking between the ages of 15 and 30 years, and 19.5% before age 15. Significantly higher smoking prevalence and daily cigarette consumption were associated with being male, single, and being more highly educated. Relief of psychological tension, boredom, and imitating others were the most important reasons for smoking, whereas health and religious considerations were the most important reasons for not smoking among never-smokers, for quitting among ex-smokers, and for attempting to quit or thinking about quitting among current smokers. About 90% of all subjects thought that they would not smoke in the future. Physicians and religious men were identified as the most effective anti-smoking advocates by a much higher proportion of respondents (44%) than nurses, health educators, and teachers (each less than 5%). Health and religious education were generally cited as more effective in deterring smoking than tobacco control laws and policies. CONCLUSIONS: Cigarette smoking is prevalent among Saudi adults in Riyadh, particularly males, most of whom begin to smoke rather early in life and continue for many years. Health and religious education should be the cornerstone for any organised tobacco control activities, which are urgently needed to combat the expected future epidemic of smoking-related health problems.




     

Propolis to Curb Lifestyle Related Disorders: An Overview

The natural products are gaining immense importance in the domain of nutrition to prevent various maladies and improve the quality of life. Among these, natural exudates are of significant worth as these biochemical compounds are released by various living entities having pharmacological properties for utilization in various drug developments. These natural exudates are the promising source for the discovery of new medications. Numerous bioactive moieties collected by honeybees from exudates and buds of particular trees and plants, considered to be utilized as defensive barrier with special reference to propolis. It generally contains numerous biochemical components, i.e., polyphenols, steroids, terpenoids, and amino acids. They also contain isoferulic acid, sinapinic acid, caffeic acid, and chrysin responsible for antibacterial perspectives. With special attention to propolis, it has been utilized in folk medicines due to several of its therapeutic activities, i.e., antioxidant, antidiabetic, anti-inflammatory, antiviral, and anticancer properties. In this context, it is extensively used in foodstuffs and beverages to improve health related disorders like inflammation, diabetes, heart disease, protects injured gums, and cancer insurgence. Moreover, it has been used to curtail stomatology, gastroenterology, skin lesions, and otorhinolaryngologic and respiration diseases.     

Effect of fortification on physico-chemical and microbiological stability of whole wheat flour

Stability of fortified whole wheat flour (WWF) was evaluated using NaFeEDTA, elemental iron, ZnSO₄ and ZnO as fortificants. Fortified WWF was stored in tin boxes and polypropylene bags for 60 days under ambient storage condition (ASC) and controlled storage condition (CSC). Fortification significantly (p ? 0.05) decreased moisture and protein content and increased ash content to 5.44%, 6% and 23%, as compared to control. Fortified WWF, assayed periodically for mould contamination manifested a significant inhibition (∼1 log reduction) in flours containing elemental iron. Low storage temperature and relative humidity (RH) indicated lower level of mould count during extended storage time. Tin boxes, as storage material, exhibited a better protection against mould attack, acting as an effective barrier for moisture. Fortificants exerted a slight deteriorative effect on texture characteristics of the chapattis made of these flours but chapattis were still accepted by the judges. Zinc fortificants seemed like having little or no effect on the quality of the flours and chapattis, made of such flours. Shelf life of fortified flour may be extended by using elemental iron as fortificant and storing the product in tin boxes under relatively low temperature and RH.     

Robust Diversity-based Sine-Cosine Algorithm for Optimizing Hydropower Multi-reservoir Systems

Hydropower energy generation depends on the available water resources. Therefore, planning and operation of the water resource systems are paramount tasks for energy management. Since reservoirs are one of the important components of water resources systems, extracting optimal operating policies for proper management of energy generated from these systems is an imperative step. Optimizing reservoir system operation (ORSO) is a non-linear, large-scale, and non-convex problem with a large number of constraints and decision variables. To solve ORSO problem effectively, a robust diversity-based, sine-cosine algorithm (RDB-SCA) is developed in the present study by introducing several strategies to balance the global exploration and local exploitation ability and to achieve accurate and reliable solutions. An efficient linear operation rule is coupled with the RDB-SCA to maximize the energy generation. The proposed method is then applied to a real-world, multi-reservoir system to extract optimal operational policies and, consequently, maximize the energy production. It is shown that the RDB-SCA is able to generate 24, 14, and 6% more energy than the original SCA, respectively for 2-, 3-, and 4-reservoir systems. The present findings are useful to suggest guidelines for efficient operation of hydropower multi-reservoir systems. This paper is supported by https://imanahmadianfar.com/codes.

     

A study on the efficiency of a capped hardening elasto-plastic model for soft clays

It is well known that the deformation and stress-resistant characteristics of fine-grained soils, especially soft clays, are significantly influenced by the soil softness. It is therefore very important to employ a model which can accurately simulate the effects of this phenomenon. A constitutive model must be able to create a balance among stress paths, the number of parameters, the process of parameter determination, and finally, the simplicity of the computational calculations.The current study investigates the performance of a two-yield surface (cone and cap yield surface) model for soft soils. The efficiency of the cap yield surface has been studied as well. The model has been calibrated by employing the data derived from previous researches for Bangkok clay. The incorporated data have been obtained from the results of CD triaxial, CU triaxial, and oedometer tests. The proposed method for the model calibration can accurately predict the triaxial test results and oedometer test stress path simultaneously. This method for predicting the soil behavior is based on the main soil characteristics taken from common soil mechanics tests. It can be widely employed for engineering practices, especially when complicated soil behavior is encountered.     

Concurrent cell formation and layout design using scatter search

Two key decisions in designing cellular manufacturing systems are cell formation and layout design problems. In the cell formation problem, machine groups and part families are determined while in the facility layout problem the location of each machine in each cell (intra-cell layout) and the location of each cell (inter-cell layout) are decided. Owing to the fact that there are interactions between two problems, cell formation and layout design problem must be tackled concurrently to design a productive manufacturing system. In this research, two problems are investigated concurrently. Some important and realistic factors such as inter-cell layout, intra-cell layout, operations sequence, part demands, batch size, number of cells, cell size, and variable process routings are incorporated in the problem. The problem is formulated as a mathematical model. Three different methods are described to solve the problem: multi-objective scatter search (MOSS), non-dominated genetic algorithm (NSGA-II), and the ε-constraint method. The methods are employed to solve nine problems generated and adopted from the literature. Sensitivity analysis is accomplished on the parameters of the problem to investigate the effects of them on objective function values. The results show that the proposed MOSS algorithm performs better than NSGA-II and produces better solutions in comparison to multi-stage approaches.     

Experimental investigation of liquid–liquid flow in an inclined pipe using dimensionless numbers

Two-phase flow is a common phenomenon in the energy industry, where flow patterns significantly affect heat transfer and pressure drop in different systems. However, there is no unique or comparable flow map because of its dependency on dimensional parameters. Therefore, an analysis using dimensionless numbers makes the results comprehensive. To do so, a series of liquid–liquid flow experiments (1296 experiments) were conducted in a transparent pipe at the different velocities of the phases. The flow patterns were captured using a high-speed camera. The experiments were performed at eight different inclinations within the range of −20 to +20 degrees. Six flow patterns are observed at different inclinations; stratified flow with mixing at the interface (STMI), dispersion of water in oil (Dw/o), dispersion of oil in water (Do/w), dual continuous (DC), slug, and wavy stratified (WST), where the first five flow patterns are presented in the upward flow and the two last flow patterns disappear in some of the downward flow. The pattern of boundaries for each flow pattern in the upward flow shows dependency on inclination, while in the downward flow condition, a rather general format can be applied to most of the patterns. The analysis illustrates that gravity and buoyancy forces are the dominating forces in the system compared to other forces, such as viscous, inertia, and interfacial tension, which are due to the inclination of the pipe.     

High-entropy oxides: Harnessing crystalline disorder for emergent functionality

High-entropy materials defy historical materials design paradigms by leveraging chemical disorder to kinetically stabilize novel crystalline solid solutions comprised of many end-members. Formulational diversity results in local crystal structures that are seldom found in conventional materials and can strongly influence macroscopic physical properties. Thermodynamically prescribed chemical flexibility provides a means to tune such properties. Additionally, kinetic metastability results in many possible atomic arrangements, including both solid-solution configurations and heterogeneous phase assemblies, depending on synthesis conditions. Local disorder induced by metastability, and extensive cation solubilities allowed by thermodynamics combine to give many high-entropy oxide systems utility as electrochemical, magnetic, thermal, dielectric, and optical materials. Though high-entropy materials research is maturing rapidly, much remains to be understood and many compositions still await discovery, exploration, and implementation.     

IgG from Adult Atopic Dermatitis (AD) Patients Induces Thymic IL-22 Production and CLA Expression on CD4+ T Cells: Possible Epigenetic Implications Mediated by miRNA

Atopic dermatitis (AD) is a common relapsing inflammatory skin disorder characterized by immune-mediated inflammation and epidermal barrier dysfunction. The pathogenesis of AD is multifactorial and has not been fully elucidated to date. This study aimed to evaluate whether serum IgG from adult AD patients could modulate the thymic maturation of IL-22-producing T cells and CLA+ T cells of non-atopic infants. Given that miRNAs regulate immune response genes, we evaluated whether miRNA expression is also altered in cultured thymocytes. Thymocytes were cultured with purified IgG from AD patients or control conditions (mock, Intravenous-IgG (IVIg), non-atopic IgG, or atopic non-AD IgG). Using flow cytometry analysis, we assessed the expression of CLA and intracellular levels of IL-4, IFN-γ, and IL-22 on double-positive T cells (DP T), CD4 T cells, or CD8 T cells. We also investigated the frequency of IgG isotypes and their direct interaction with the thymic T cells membrane. The miRNA profiles were evaluated by the Illumina small RNA-seq approach. MiRNA target gene prediction and enrichment analyses were performed using bioinformatics. Increased frequencies of IL-22 and CLA+ producing CD4+ T cells cultured with IgG of AD patients was seen in non-atopic infant thymocytes compared to all control conditions. No alterations were observed in the frequency of IgG isotypes among evaluated IgG pools. Evidence for a direct interaction between IgG and thymic DP T, CD4 T, and CD8 T cells is presented. The small RNA-seq analysis identified ten mature miRNAs that were modulated by AD IgG compared to mock condition (miR-181b-5p, hsa-miR-130b-3p, hsa-miR-26a-5p, hsa-miR-4497, has-miR-146a, hsa-let-7i-5p, hsa-miR-342-3p, has-miR-148a-3p, has-miR-92a and has-miR-4492). The prediction of the targetome of the seven dysregulated miRNAs between AD and mock control revealed 122 putative targets, and functional and pathway enrichment analyses were performed. Our results enhance our understanding of the mechanism by which IgG can collaborate in thymic T cells in the setting of infant AD.     

Development of the Acidity of Zirconia-Supported Niobia Catalysts

A series of NbO _x /ZrO₂ catalysts containing up to 2.67wt Nb (ca. 80 nominal surface coverage) was prepared by incipient wetness impregnation from niobium oxalate and oxalic acid solution. The structure of the catalysts was monitored by X-ray diffraction and Raman spectroscopy. The results indicated the presence of a surface Nb phase. No evidence for the formation of crystalline Nb₂O₅ species was found. The development of the acidity as a function of Nb loading was monitored by adsorption of a basic probe molecule followed by infrared spectroscopy. The results indicated the appearance of Brnsted acid sites for a threshold of Nb loading. The abundance of Brnsted acid sites correlated well with the isopropanol dehydration activity. The overall behavior was very similar to that reported earlier for the WO _x /ZrO₂ system.