全文获取类型
收费全文 | 524779篇 |
免费 | 7664篇 |
国内免费 | 1468篇 |
专业分类
电工技术 | 9559篇 |
综合类 | 526篇 |
化学工业 | 78664篇 |
金属工艺 | 19964篇 |
机械仪表 | 15191篇 |
建筑科学 | 12668篇 |
矿业工程 | 2269篇 |
能源动力 | 14516篇 |
轻工业 | 47056篇 |
水利工程 | 5219篇 |
石油天然气 | 9334篇 |
武器工业 | 37篇 |
无线电 | 59915篇 |
一般工业技术 | 101762篇 |
冶金工业 | 103506篇 |
原子能技术 | 10558篇 |
自动化技术 | 43167篇 |
出版年
2022年 | 3159篇 |
2021年 | 4892篇 |
2020年 | 3479篇 |
2019年 | 4554篇 |
2018年 | 7808篇 |
2017年 | 7607篇 |
2016年 | 7934篇 |
2015年 | 5559篇 |
2014年 | 9241篇 |
2013年 | 24066篇 |
2012年 | 14625篇 |
2011年 | 20142篇 |
2010年 | 15799篇 |
2009年 | 17700篇 |
2008年 | 18091篇 |
2007年 | 17777篇 |
2006年 | 15503篇 |
2005年 | 14210篇 |
2004年 | 13602篇 |
2003年 | 13399篇 |
2002年 | 12633篇 |
2001年 | 12831篇 |
2000年 | 11869篇 |
1999年 | 12595篇 |
1998年 | 32812篇 |
1997年 | 22897篇 |
1996年 | 17446篇 |
1995年 | 13036篇 |
1994年 | 11284篇 |
1993年 | 10974篇 |
1992年 | 7913篇 |
1991年 | 7418篇 |
1990年 | 7262篇 |
1989年 | 7014篇 |
1988年 | 6468篇 |
1987年 | 5767篇 |
1986年 | 5655篇 |
1985年 | 6265篇 |
1984年 | 5900篇 |
1983年 | 5171篇 |
1982年 | 4900篇 |
1981年 | 4966篇 |
1980年 | 4705篇 |
1979年 | 4609篇 |
1978年 | 4408篇 |
1977年 | 5334篇 |
1976年 | 6971篇 |
1975年 | 3796篇 |
1974年 | 3551篇 |
1973年 | 3665篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
111.
Simutin A. N. Deineko A. V. Zertsalov M. G. 《Power Technology and Engineering (formerly Hydrotechnical Construction)》2021,55(4):482-486
Power Technology and Engineering - The monitoring of hydraulic structures as high-risk facilities is discussed. Monitoring should ensure the reliability and functioning of a hydraulic structure... 相似文献
112.
Mining high utility itemsets (HUIs) from transaction databases considers such factors as the unit profit and quantity of purchased items. Two-phase tree-based algorithms transform a database into compressed tree structures and generate candidate patterns through a recursive pattern-growth procedure. This procedure requires a lot of memory and time to construct conditional pattern trees. To address this issue, this study employs two compressed tree structures, namely, Utility Count Tree and String Utility Tree, to enumerate valid patterns and thus promote fast utility computation. Furthermore, the study presents an algorithm called single-phase utility computation (SPUC) that leverages these two tree structures to mine HUIs in a single phase by incorporating novel pruning strategies. Experiments conducted on both real and synthetic datasets demonstrate the superior performance of SPUC compared with IHUP, UP-Growth, and UP-Growth+ algorithms. 相似文献
113.
Chertkov Yu. B. Anikin M. N. Lebedev I. I. Naimushin A. G. Smol’nikov N. V. 《Atomic Energy》2021,131(1):42-45
Atomic Energy - The results of calculations and experimental determination of the neutronics characteristics of the IRT-T research reactor are presented. The IRT-T reactor is a pool reactor with... 相似文献
114.
Spiridonova E. A. Rotko V. O. Samonin V. V. Podvyaznikov M. L. 《Protection of Metals and Physical Chemistry of Surfaces》2021,57(1):45-51
Protection of Metals and Physical Chemistry of Surfaces - In this work, a universal sorbent has been obtained that works according to the mechanisms of chemisorption and adsorption by impregnating... 相似文献
115.
Dr. Alejandra A. Carriles Alberto Mills Dr. María-José Muñoz-Alonso Dr. Dolores Gutiérrez Dr. Juan M. Domínguez Prof. Dr. Juan A. Hermoso Prof. Dr. Federico Gago 《Chembiochem : a European journal of chemical biology》2021,22(2):374-391
Spontaneous mutations in the EEF1A2 gene cause epilepsy and severe neurological disabilities in children. The crystal structure of eEF1A2 protein purified from rabbit skeletal muscle reveals a post-translationally modified dimer that provides information about the sites of interaction with numerous binding partners, including itself, and maps these mutations onto the dimer and tetramer interfaces. The spatial locations of the side chain carboxylates of Glu301 and Glu374, to which phosphatidylethanolamine is uniquely attached via an amide bond, define the anchoring points of eEF1A2 to cellular membranes and interorganellar membrane contact sites. Additional bioinformatic and molecular modeling results provide novel structural insight into the demonstrated binding of eEF1A2 to SH3 domains, the common MAPK docking groove, filamentous actin, and phosphatidylinositol-4 kinase IIIβ. In this new light, the role of eEF1A2 as an ancient, multifaceted, and articulated G protein at the crossroads of autophagy, oncogenesis and viral replication appears very distant from the “canonical” one of delivering aminoacyl-tRNAs to the ribosome that has dominated the scene and much of the thinking for many decades. 相似文献
116.
Byakova O. V. Stepanov G. V. Vlasov A. O. Danylyuk V. E. Semenov N. V. Berezovs’kyi O. M. Gnyloskurenko S. V. 《Strength of Materials》2019,51(5):726-734
Strength of Materials - The paper addresses the investigation of high-strain rate compressive behavior of Al foams subjected to impact at the intermediate striking velocity ranged from 40 to... 相似文献
117.
Theoretical Foundations of Chemical Engineering - Using chemical and XRD phase analysis, along with electron microscopy, the hydrolytic processing of metallic bismuth into high-purity citrate has... 相似文献
118.
Bram H. Frohock Jessica M. Gilbertie Dr. Jennifer C. Daiker Dr. Lauren V. Schnabel Dr. Joshua G. Pierce 《Chembiochem : a European journal of chemical biology》2020,21(7):933-937
The failure of frontline antibiotics in the clinic is one of the most serious threats to human health and requires a multitude of novel therapeutics and innovative approaches to treatment so as to curtail the growing crisis. In addition to traditional resistance mechanisms resulting in the lack of efficacy of many antibiotics, most chronic and recurring infections are further made tolerant to antibiotic action by the presence of biofilms. Herein, we report an expanded set of 5-benzylidene-4-oxazolidinones that are able to inhibit the formation of Staphylococcus aureus biofilms, disperse preformed biofilms, and, in combination with common antibiotics, are able to significantly reduce the bacterial load in a robust collagen-matrix model of biofilm infection. 相似文献
119.
Lorena Rodríguez-López Myriam Rincón-Fontán Xanel Vecino Ana B. Moldes Jose M. Cruz 《Journal of surfactants and detergents》2020,23(1):79-90
Over the last few years, the global biosurfactant market has raised due to the increasing awareness among consumers, for the use of biological or bio-based products. Because of their composition, it can be speculated that these are more biocompatible and more biodegradable than their chemical homologous. However, at the moment, no studies exist in the literature about the biodegradability of biosurfactants. In this work, a biosurfactant contained in a crude extract, obtained from a corn wet-milling industry stream that ferments spontaneously in the presence of lactic acid bacteria, was subjected to a biodegradation study, without addition of external microbial biomass, under different conditions of temperature (5–45 °C), biodegradation time (15–55 days), and pH (5–7). For that, a Box–Behnken factorial design was applied, which allowed to predict the percentage of biodegradation for the biosurfactant contained in the crude extract, between the range of the independent variables selected in the study, obtaining biodegradation values between 3 and 80%. The percentage of biodegradation for the biosurfactant was calculated based on the increase in the surface tension of samples of the crude extract. Furthermore, it was also possible to predict the variation in t1/2 for the biosurfactant (time to achieve the 50% of biodegradation) under different conditions. 相似文献
120.
Changmo Kim Izhar Livne‐Bar Karsten Gronert Jeremy M. Sivak 《Molecular nutrition & food research》2020,64(4)
Lipoxins (LXs) are autacoids, specialized proresolving lipid mediators (SPMs) acting locally in a paracrine or autocrine fashion. They belong to a complex superfamily of dietary small polyunsaturated fatty acid (PUFA)–metabolites, which direct potent cellular responses to resolve inflammation and restore tissue homeostasis. Together, these SPM activities have been intensely studied in systemic inflammation and acute injury or infection, but less is known about LX signaling and activities in the central nervous system. LXs are derived from arachidonic acid, an omega‐6 PUFA. In addition to well‐established roles in systemic inflammation resolution, they have increasingly become implicated in regulating neuroinflammatory and neurodegenerative processes. In particular, chronic inflammation plays a central role in Alzheimer's disease (AD) etiology, and dysregulated LX production and activities have been reported in a variety of AD rodent models and clinical tissue samples, yet with complex and sometimes conflicting results. In addition, reduced LX production following retinal injury has been reported recently by the authors, and an intriguing direct neuronal activity promoting survival and homeostasis in retinal and cortical neurons is demonstrated. Here, the authors review and clarify this growing literature and suggest new research directions to further elaborate the role of lipoxins in neurodegeneration. 相似文献