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排序方式: 共有3911条查询结果,搜索用时 15 毫秒
41.
42.
M Takahashi F Sasaki T Namieno T Matsuhisa Y Okawa K Taguchi H Takahashi J Uchino 《Canadian Metallurgical Quarterly》1998,13(2-3):191-192
A 3-year child presented with episodic lower abdominal pain; during the eighth attack, a mass was palpable in the left upper quadrant, and a barium enema revealed a stenotic area in the transverse colon. This was resected and an uneventful postoperative course followed. Subsequently, the child has remained symptom-free. instruments are no longer in use. 相似文献
43.
44.
M Sasaki Y Hattori F Tomita K Moriishi M Kanno T Kohya K Oguma A Kitabatake 《Canadian Metallurgical Quarterly》1998,125(8):1651-1660
1. The aim of this study was to determine whether different signal transduction mechanisms underlie the Ca2+ sensitizing effects of guanosine 5'-O-(3-thiotriphosphate) (GTP(gamma)S) and receptor agonists on beta-escin-skinned smooth muscle of rabbit mesenteric artery. 2. In the homogenate of the beta-escin-skinned arterial strip, C3 exoenzyme of Clostridium botulinum catalyzed the [32P]-ADP-ribosylation of only one protein that had the same molecular mass as the protein detected in Western blots with anti-rho p21 antibody. Pretreatment of preparations with C3 resulted in great inhibition of GTP(gamma)S-induced Ca2+ sensitization, although the effect of GTP(gamma)S at higher concentrations (> or = 30 microM) was not completely blocked by this treatment. In contrast, the enhancement by phenylephrine and histamine, in the presence of guanosine 5'-triphosphate, of the Ca2+-induced contraction was not affected by C3 pretreatment. 3. The protein kinase C (PKC) inhibitors calphostin C and staurosporine completely eliminated the enhancement by phorbol ester 12,13-dibutyrate of the Ca2+-induced contraction. However, these PKC inhibitors had no effect on GTP(gamma)S- and receptor agonist-induced Ca2+ sensitization. 4. The tyrosine kinase inhibitors genistein and tyrphostin 25 caused an irreversible and complete block of the enhancement by GTP(gamma)S of the Ca2+-induced contraction without affecting this Ca2+ contraction. The inactive genistein analogue daidzein did not modify the effect of GTP(gamma)S. The Ca2+ sensitizing effects of phenylephrine and histamine were also blocked by these tyrosine kinase inhibitors. 5. These results suggest that rho p21 predominantly mediates GTP(gamma)S-induced Ca2+ sensitization of beta-escin-skinned smooth muscle of rabbit mesenteric artery, while the Ca2+ sensitizing actions of heterotrimeric G protein-coupled receptor agonists do not involve this small G protein. However, it seems that tyrosine phosphorylation, but not PKC activation, plays an important role in both of the rho p21 protein- and heterotrimeric G protein-mediated Ca2+ sensitization mechanisms. 相似文献
45.
K Yoshida M Yoshimoto K Sasaki T Ohnishi T Ushiki J Hitomi S Yamamoto M Sigeno 《Canadian Metallurgical Quarterly》1998,74(4):1654-1657
A new stable substrate applicable to the observation of DNA molecules by atomic force microscopy (AFM) was fabricated from a ultrasmooth sapphire (alpha-Al2O3 single crystal) plate. The atomically ultrasmooth sapphire as obtained by high-temperature annealing has hydrophobic surfaces and could not be used for the AFM observation of DNA. However, sapphire treated with Na3PO4 aqueous solution exhibited a hydrophilic character while maintaining a smooth surface structure. The surface of the wet-treated sapphire was found by x-ray photoelectron spectroscopy and AFM to be approximately 0.3 nm. The hydrophilic surface character of the ultrasmooth sapphire plate made it easy for DNA molecules to adhere to the plate. Circular molecules of the plasmid DNA could be imaged by AFM on the hydrophilic ultrasmooth sapphire plate. 相似文献
46.
Criteria for evaluating flexibility of a generation mix are presented, and an efficient computational algorithm for determining a flexible generation mix considering uncertainties in the power system expansion planning is developed. The flexible generation mix problem is formulated as a multiobjective optimization problem and solved by the dynamic programming technique in which type of generation plant is selected as a stage and generation capacity is selected as a state. The proposed method can treat easily not only the uncertainties but also many constraints of generation planning such as integer solutions of generation capacities, reliability constraints, and so on. The effectiveness and feasibility of the proposed method are demonstrated on a typical power system model 相似文献
47.
Hiroyuki Sugiyama Takuto Sekiguchi Ryosuke Matsumura Shunpei Yamashita Yoshihiro Suda 《Multibody System Dynamics》2012,27(1):55-74
In railroad turnouts, geometries of tongue and crossing rails are very complex and their shapes are changing along the track.
Therefore, wheels are subjected to not only tread and flange contacts, but also the back-of-flange and top-of-flange contacts
in the case of spring switches of tram vehicles. For this reason, one needs to deal with significant jumps in contact points
for solving wheel/rail contact problems in turnout, and an accurate prediction of jumps in contact points is one of the most
important issues that need to be carefully handled in the dynamic simulation of vehicle/turnout interactions. In this investigation,
a numerical procedure that can be used for solving such a complex wheel/rail contact problem in turnout is proposed. In particular,
a combined nodal and non-conformal contact approach is developed such that significant jumps in contact points are detected
using the nodal search, while the exact location of contact point is then determined with continuous surface parameterizations
using non-conformal contact equations. With this combined nodal and non-conformal contact approach for the contact geometry
analysis of vehicle/turnout interactions, multiple look-up contact tables can be generated in an efficient way without losing
accuracy. Since detailed contact search is performed off-line to obtain look-up contact tables, significant changes in contact
points in turnout can be efficiently predicted on-line with tabular data to be interpolated in a standard way. Several numerical
examples are presented in order to demonstrate the use of the numerical procedure developed in this investigation. 相似文献
48.
Yuji Fukaishi Yoshihiro Ohta Kohji Higuchi Eiji Takegami Satoshi Tomioka Kosin Chamnongthai 《Artificial Life and Robotics》2012,17(1):1-6
A robust DC?CDC converter which can covers extensive load change and also input voltage changes with one controller is needed. Then the demand to suppress output voltage change becomes still severer. We propose an approximate 2-degree-of-freedom (2DOF) digital controller which realized start-up response and dynamic load response independently. The controller makes a control bandwidth wider, and at the same time makes variations of the output voltage small at sudden changes of a load and an input voltage. In this paper, a new approximate 2DOF digital control system with additional zeros is proposed. Using the additional zeros, the second-order differential transfer characteristics between equivalent disturbances and a output voltage are realized. Therefore, the new controller makes variations of the output voltage smaller and the sudden changes of the load and the input voltage. This controller is actually implement on a DSP and is connected to the DC?CDC converter. Experimental results demonstrate that this type of digital controller can satisfy given severe specifications with low frequency sampling. 相似文献
49.
Rod-shaped BaTiO3 powder particles have been prepared from rod-shaped TiO2 ·nH2O and BaCO3 in molten chloride. The morphology of BaTiO3 particles was studied referring to the effects of the chemical species of the starting titanium compound, amount of chloride, particle size of the titanium compound and reaction conditions, and the preparation condition of rod-shaped BaTiO3 has been determined: i.e., large TiO2 ·nH2O particles were heated at 700°C in molten salt with an equal amount of BaTiO3. This condition was effective in suppressing the formation of BaTiO3 by a solution-precipitation process as well as the deformation of either TiO2 ·nH2O or BaTiO3, which are responsible for the formation of equiaxed BaTiO3 particles. The obtained rod-shaped BaTiO3 particles had a cubic symmetry. Electron diffraction analysis showed that the following topotactic relation is retained; 0 1 0potassium tetratitanate 0 1 0hydrated titania 1 0 0anatase 1 0 0barium titanate 相似文献
50.
The generation of surface roughness during slurry erosion-corrosion and its effect on the pitting potential 总被引:1,自引:0,他引:1
Results of experiments performed to isolate the effect of surface roughness generated during slurry erosion-corrosion of 304L stainless steel are presented. Surfaces prepared by grinding to different finishes show that increasing the roughness lowers the pitting potential in chloride solution. Subsequent erosion by an aqueous sand slurry then alters this pitting potential (Ep), as measured in the solution phase alone, in a manner dependent on the initial surface roughness. Surfaces which were initially rougher show a pronounced rise in p after erosion, while those with an initially smoother finish show a fall in Ep after erosion. Measurement of Ep during erosion-corrosion does not fit either process, with values of Ep lower than those predicted from the surface roughness alone. 相似文献