Prediction of Children's Empathy-Related Responding From Their Effortful Control and Parents' Expressivity.

In this study, the linear and interactive relations of children's effortful control and parents' emotional expressivity to children's empathy-related responses were examined. Participants were 214 children, 4.5 to 8 years old. Children's effortful control was negatively related to their personal distress and was positively related to their sympathy. Parents' positive expressivity was marginally negatively related to children's personal distress and was marginally positively related to children's dispositional sympathy. Parents' negative expressivity was positively related to children's personal distress, but primarily at high levels of children's effortful control. Moreover, parents' negative expressivity was negatively related to children's situational sympathy at low levels of effortful control but was positively related to children's dispositional sympathy at high levels of effortful control. There were also quadratic relations between the measures of parents' expressivity and children's empathy-related responses. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Coping and adaptation following acute spinal cord injury: a theoretical analysis

Coping and adaptation theory is used to synthesis existing data concerning psychological recovery from acute spinal cord injury. Psychological reactions to spinal cord trauma are similar to those of mourning and other situations of severe loss. Each reaction plays a specific role in fostering or hindering recovery depending upon when it occurs. Premorbid personality and the influence of significant others play a central role in coping with injury. These factors partly explain why some patients cope better than others to equally serious disability. A critique of research methodologies and suggestions for new studies are provided.     

Operational Improvements in Image Orthicon Camera Equipment

A modern broadcast TV Camera adaptable for use with either 3-inch or 4?-inch image orthicon tubes is described. Circuit and mechanical innovations are discussed which result in improved stability and reliability. Simplified operation and maintenance of the camera are emphasized.     

Tolerance to the hyperthermic effect of morphine in the rat is a learned response.

Results of 3 experiments with 84 male Wistar rats indicate that the hyperthermic effect of morphine in rats becomes attenuated over the course of successive administrations by a conditional, compensatory, hypothermic response elicited by cues present at the time of morphine administration, thus accounting for hyperthermic tolerance. Ss with a history of morphine administration displayed a tolerant response to the hyperthermic effect of the drug and a compensatory hypothermia following a placebo if these substances were administered following cues that previously signaled morphine—neither the tolerant reaction to morphine nor the hypothermic response to the placebo resulted when Ss were injected following cues that previously signaled injection of physiological saline (Exp I). Presenting environmental cues previously associated with morphine, but without the drug, abolished established tolerance, that is, pyretic tolerance could be extinguished (Exp II). Placebo sessions interspersed between morphine sessions impeded the acquisition of tolerance, that is, pyretic tolerance was retarded by partial reinforcement (Exp III). (52 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

LAND USE AND FLOOD RISK THROUGH CATCHMENT FLOOD-MANAGEMENT PLANS

Catchment Flood Management Plans involve a high-level assessment of current flood risk and attempt to demonstrate how this risk could change with time. An influencing factor will be the changes to rural and urban land use on catchment hydraulics. By assessing a range of land use and urban-growth scenarios catchment wide, a 'catchment flood management plan' can demonstrate the cumulative effect on downstream flood-risk areas. 'Catchment flood management plan' methods also indicate how long-term land-use and climate changes can expose new areas to more frequent flooding. Techniques to assess these issues, up to a 50-year horizon, have been established as part of these pilot studies. In addition to briefly describing how land-use concerns are integrated into such concepts, this paper outlines how flood-management planning must evolve as a dynamic tool, to fulfil an on-going requirement for future development assessment.     

Aminohydroxybutane bisphosphonate and clenbuterol prevent bone changes and retard muscle atrophy respectively in tail-suspended rats

Hind-limb unloading by tail suspension of rats, an established model of simulated microgravity, was used to examine the efficacy of aminohydroxybutane bisphosphonate (AHBuBP) and clenbuterol in preventing bone loss and muscle atrophy, respectively. Male Sprague-Dawley rats (299-372 g) were randomized into six groups of six: 1) unsuspended, saline, 2) unsuspended, saline, pair fed with group 3, 3) suspended, saline, 4) suspended, 0.03 mg/kg/day x 2 of AHBuBP, 5) suspended, 0.3 mg/kg/day x 2 of AHBuBP and 6) suspended, 0.3 mg/kg/day x 2 of AHBuBP + clenbuterol (0.5 mg/kg/day i.p. x 6, then 1 mg/kg/day i.p. x 6). Animals in groups 3 to 6 were tail suspended for 14 days from a system of double pulleys and allowed free mobility with their hind limbs unloaded. On days -2 and -1, before suspension on day 0, all rats received a single s.c. injection of either 2 ml/kg of normal saline (vehicle) or AHBuBP. All rats were tested for exercise tolerance before day -2 and on day 10, and grip strength before day -2 and on day 13. On day 14, the rats were euthanized and their humeri, tibias and femurs analyzed in vitro for bone density (by single-photon absorptiometry), strength and stiffness (by 3-point bending). Muscles were analyzed for weight, protein concentration and enzyme activity. Pair feeding had no effect other than on food consumption and body weight. AHBuBP caused a dose-dependent increase in bone density in humeri, tibias and femurs, even in tail-suspended rats, relative to control unsuspended animals, with no significant difference in bone strength or stiffness between AHBuBP groups and unsuspended animals.(ABSTRACT TRUNCATED AT 250 WORDS)     

A zipper-like duplex in DNA: the crystal structure of d(GCGAAAGCT) at 2.1 A resolution

BACKGROUND: The replication origin of the single-stranded (ss)DNA bacteriophage G4 has been proposed to fold into a hairpin loop containing the sequence GCGAAAGC. This sequence comprises a purine-rich motif (GAAA), which also occurs in conserved repetitive sequences of centromeric DNA. ssDNA analogues of these sequences often show exceptional stability which is associated with hairpin loops or unusual duplexes, and may be important in DNA replication and centromere function. Nuclear magnetic resonance (NMR) studies indicate that the GCGAAAGC sequence forms a hairpin loop in solution, while centromere-like repeats dimerise into unusual duplexes. The factors stabilising these unusual secondary structure elements in ssDNA, however, are poorly understood. RESULTS: The nonamer d(GCGAAAGCT) was crystallised as a bromocytosine derivative in the presence of cobalt hexammine. The crystal structure, solved by the multiple wavelength anomalous dispersion (MAD) method at the bromine K-edge, reveals an unexpected zipper-like motif in the middle of a standard B-DNA duplex. Four central adenines, flanked by two sheared G.A mismatches, are intercalated and stacked on top of each other without any interstrand Watson-Crick base pairing. The cobalt hexammine cation appears to participate only in crystal cohesion. CONCLUSIONS: The GAAA consensus sequence can dimerise into a stable zipper-like duplex as well as forming a hairpin loop. The arrangement closes the minor groove and exposes the intercalated, unpaired, adenines to the solvent and DNA-binding proteins. Such a motif, which can transform into a hairpin, should be considered as a structural option in modelling DNA and as a potential binding site, where it could have a role in DNA replication, nuclease resistance, ssDNA genome packaging and centromere function.     

Physical therapists' perception of patients' pain and its effect on management

BACKGROUND AND PURPOSE: The purpose of this qualitative study was twofold: (1) to determine the factors that affected physical therapists' (PTs) perception of patients' pain and (2) to determine how this perception affected the management of patients. METHODS: Forty-six PTs with at least two years' experience practicing in pain management clinics, outpatient clinics or sports medicine clinics were interviewed. The data collected were transcribed, coded and analyzed for main themes. RESULTS: The most predominant factors found to affect PTs' perception of patients' pain were the therapist's personal and professional experience, area of practice and evaluative findings. CONCLUSIONS: In this sample there exists a common link between experience and evaluative findings: the longer PTs have been practicing the more proficient they become in performing and interpreting a thorough subjective and objective evaluation. PTs practicing in pain clinics were found to have a more holistic and multidisciplinary approach to patient care, whereas therapists practicing in outpatient and sports medicine facilities were more apt to focus on patients' physical symptoms and complaints. Four main themes of perceived patient pain and their corresponding management were developed: (1) patients presenting with legitimate/acute pain profiles render a slow, conservative approach by the PT; (2) patients presenting with debilitating/chronic pain were most often treated with an approach that stressed functional gains and patient independence; (3) the preferred treatment of patients characterized with a non-legitimate pain profile was an aggressive and multidisciplinary approach; (4) 'special cases' and their management were dependent upon the patient's functional level and pain tolerance.     

Spatial factors in visual attention: A reply to Crassini.

Notes that distances between stimuli and compactness of stimulus subsets are pervasive determiners of discrimination and classification performance. Contrary to B. Crassini (see record 1986-26308-001), these factors are sufficient to account for the major patterns in the chronometric data of the present authors (see PA, Vols 61:259 and 71:3057). Other factors, such as the dichotomous one distinguishing what Crassini terms unitary and nonunitary subsets, may exert some additional influence. But a convincing demonstration would require formulation of a quantitative model capable of being pitted against the present authors' distance-based model within the context of their entire body of data. (22 ref) (PsycINFO Database Record (c) 2011 APA, all rights reserved)