26 clinician trainees' recollections of experiences in a diagnostic preschool program were analyzed in terms of strength and weaknesses of the program. 相似文献
Earlier researchers like Turkeli, suggested that ‘the factors which determine the productivity of scientists are admittedly
complex and perhaps not amenable to real scientific analysis′. The present investigation was designed with the sole purpose
of confronting such a complex problem. Nearly 200 variables influencing research productivity were collected through relevant
literature, analysis of biographies of great scientists, and discussion with eminent scientists. Finally, through a critical
examination, 80 variables were selected for the use of Q-sort technique. The sample for the study consisted of a cross section
of scientists ranging from Fellows of Indian National Science Academy to young agricultural scientists. Mailed questionnaires
and personal interview methods were used for collecting data. Out of a total of 912 respondents, reply was obtained from 325.
On the basis of Q-sorted data, 26 variables were selected for further analysis and they were subjected to principal component
factor analysis. The results indicated eleven factors affecting research productivity of scientists. They were: persistence,
resource adequacy, access to literature, initiative, intelligence, creativity, learning capability, stimulative leadership,
concern for advancement, external orientation, and professional commitment. 相似文献
1. Calcium disodium ethylenediaminetetraacetate (CaNa2 EDTA) and meso-2,3-dimercaptosuccinic acid (DMSA) individually and in permutation-combination in various doses (0.1, 0.2 and 0.4 mmol/kg bodyweight) were investigated for their efficacy to mobilize lead from vital tissues into urine and faeces and to restore the lead-sensitive biochemical parameters in lead pre-exposed rats with a view to develop the most acceptable treatment regimen for lead poisoning with a minimal loss of endogenous essential elements. 2. The combined therapy was more effective than a single chelator treatment. 3. The combination of 0.2 mmol/kg CaNa2EDTA + 0.4 mmol/kg DMSA caused a lower depletion of zinc, calcium and iron but possessed almost equal capability to that of 0.4 mmol/kg CaNa2EDTA + 0.4 mmol/kg DMSA to produce urinary as well as faecal excretion of lead, to reduce the tissue burden of lead, including that of the brain, and to reverse lead-induced biochemical alterations. 4. The combination of 0.2 mmol/kg CaNa2EDTA + 0.4 mmol/kg DMSA has shown a definite improvement over previously reported combinations in terms of removal of lead from tissues, particularly the brain, restoration of urinary delta-aminolevulinic acid levels and a decrease in the loss of body zinc and is, therefore, recommended for the treatment of lead intoxication. 相似文献
Keratan sulfate proteoglycans (KSPGs) are the major proteoglycans of the cornea and are secreted by keratocytes in the corneal stroma. Previous studies have been able to show only transient secretion of KSPG in cell culture. In this study, cultures of bovine keratocytes were found to secrete the three previously characterized KSPG proteins into culture medium. Reactivity with monoclonal antibody I22 demonstrated substitution of these proteins with keratan sulfate chains. KSPG constituted 15% of the proteoglycan metabolically labeled with [35S]sulfate in keratocyte culture medium. This labeled KSPG contained keratan sulfate chains of 4700 Da compared to 21,000 Da for bovine corneal keratan sulfate. Labeled keratan sulfate from cultures contained nonsulfated, monosulfated, and disulfated disaccharides that were released by digestion with endo-beta-galactosidase or keratanase II. Nonsulfated disaccharides were relatively more abundant in keratan sulfate from culture than in corneal keratan sulfate. These results show that cultured bovine keratocytes maintain the ability to express all three of the known KSPG proteins, modified with keratan sulfate chains and sulfated on both N-acetylglucosamine and galactose moieties. KSPG made in vitro differs from that found in vivo in the length and sulfation of its keratan sulfate chains. The availability of cell cultures secreting corneal keratan sulfate proteoglycans provides an opportunity to examine biosynthesis and control of this important class of molecules. 相似文献
2014 aluminium alloy was subjected to various thermomechanical ageing (TMA) treatments which included partial peak ageing (25% and 50%), warm rolling (10% and 20%) and further ageing to peak hardness level at 160 ° C. The tensile tests reveal that TMA treatments cause a substantial improvement in tensile properties and thermal stability. The electron microscopic studies reveal that the TMA treatments affect substantially the ageing characteristics. The TMA Ib treatment yields the finest needles having longitudinal dimensions of 40nm. The TMA treatments also lead to precipitate-dislocation networks of different densities. It is observed that TMA IIb treatment results in the densest precipitate-dislocation tangles of all the TMA treatments. As a result, a significant improvement in the tensile properties of 2014 aluminium alloy has been observed. 相似文献
In real world, the automatic detection of liver disease is a challenging problem among medical practitioners. The intent of this work is to propose an intelligent hybrid approach for the diagnosis of hepatitis disease. The diagnosis is performed with the combination of k‐means clustering and improved ensemble‐driven learning. To avoid clinical experience and to reduce the evaluation time, ensemble learning is deployed, which constructs a set of hypotheses by using multiple learners to solve a liver disease problem. The performance analysis of the proposed integrated hybrid system is compared in terms of accuracy, true positive rate, precision, f‐measure, kappa statistic, mean absolute error, and root mean squared error. Simulation results showed that the enhanced k‐means clustering and improved ensemble learning with enhanced adaptive boosting, bagged decision tree, and J48 decision tree‐based intelligent hybrid approach achieved better prediction outcomes than other existing individual and integrated methods. 相似文献
The extensively utilized tool to detect novel coronavirus (COVID-19) is a real-time polymerase chain reaction (RT-PCR). However, RT-PCR kits are costly and consume critical time, around 6 to 9 hours to classify the subjects as COVID-19(+) or COVID-19(-). Due to the less sensitivity of RT-PCR, it suffers from high false-negative results. To overcome these issues, many deep learning models have been implemented in the literature for the early-stage classification of suspected subjects. To handle the sensitivity issue associated with RT-PCR, chest CT scans are utilized to classify the suspected subjects as COVID-19 (+), tuberculosis, pneumonia, or healthy subjects. The extensive study on chest CT scans of COVID-19 (+) subjects reveals that there are some bilateral changes and unique patterns. But the manual analysis from chest CT scans is a tedious task. Therefore, an automated COVID-19 screening model is implemented by ensembling the deep transfer learning models such as Densely connected convolutional networks (DCCNs), ResNet152V2, and VGG16. Experimental results reveal that the proposed ensemble model outperforms the competitive models in terms of accuracy, f-measure, area under curve, sensitivity, and specificity.
The Journal of Supercomputing - Cluster-based routing protocols have been proven efficient in prolonging the life cycle of wireless sensor networks (WSNs). Periodic and multi-hop clustering are the... 相似文献
Neural Computing and Applications - Grouping the sensor nodes into clusters is an effective way to organize wireless sensor networks and to prolong the networks’ lifetime. This paper presents... 相似文献