全文获取类型
收费全文 | 233篇 |
免费 | 7篇 |
国内免费 | 1篇 |
专业分类
电工技术 | 3篇 |
综合类 | 1篇 |
化学工业 | 49篇 |
金属工艺 | 3篇 |
机械仪表 | 1篇 |
建筑科学 | 4篇 |
能源动力 | 11篇 |
轻工业 | 23篇 |
水利工程 | 2篇 |
石油天然气 | 1篇 |
无线电 | 47篇 |
一般工业技术 | 55篇 |
冶金工业 | 22篇 |
原子能技术 | 1篇 |
自动化技术 | 18篇 |
出版年
2024年 | 1篇 |
2023年 | 4篇 |
2022年 | 8篇 |
2021年 | 11篇 |
2020年 | 10篇 |
2019年 | 10篇 |
2018年 | 14篇 |
2017年 | 12篇 |
2016年 | 9篇 |
2015年 | 8篇 |
2014年 | 8篇 |
2013年 | 16篇 |
2012年 | 10篇 |
2011年 | 11篇 |
2010年 | 12篇 |
2009年 | 17篇 |
2008年 | 11篇 |
2007年 | 7篇 |
2006年 | 7篇 |
2005年 | 3篇 |
2004年 | 7篇 |
2003年 | 4篇 |
2002年 | 1篇 |
2001年 | 1篇 |
1999年 | 2篇 |
1998年 | 8篇 |
1997年 | 4篇 |
1996年 | 2篇 |
1995年 | 3篇 |
1994年 | 1篇 |
1992年 | 1篇 |
1987年 | 1篇 |
1986年 | 1篇 |
1985年 | 1篇 |
1984年 | 2篇 |
1983年 | 2篇 |
1982年 | 2篇 |
1978年 | 2篇 |
1977年 | 1篇 |
1976年 | 2篇 |
1975年 | 2篇 |
1972年 | 1篇 |
1966年 | 1篇 |
排序方式: 共有241条查询结果,搜索用时 15 毫秒
71.
Ridhima Wadhwa Keshav Raj Paudel Li Hian Chin Chian Ming Hon Thiagarajan Madheswaran Gaurav Gupta Jithendra Panneerselvam Thangavelu Lakshmi Sachin Kumar Singh Monica Gulati Harish Dureja Alan Hsu Meenu Mehta Krishnan Anand Hari Prasad Devkota Jestin Chellian Dinesh Kumar Chellappan Philip M. Hansbro Kamal Dua 《Journal of Food Biochemistry》2021,45(1):e13572
72.
This article traces the development of acyclic cucurbit[n]uril-type receptors with a focus on work from the Isaacs group. First, we describe the synthesis of methylene bridged glycoluril dimers capped with aromatic sidewalls which allowed us to probe the interconversion of the S- and C-shaped dimers which is a fundamental step in CB[n] formation. The C-shaped compounds were found to undergo discrete self-assembly (dimerization) in both water and organic solvents which lead us to investigate multicomponent self-sorting systems. We supressed the self-association of 8 by electrostatic repulsion in the putative dimer which allowed expression of its innate molecular recognition properties toward methylene blue and related planar cationic dyes. Longer glycoluril oligomers (trimer-hexamer, acyclic decamer) were prepared by starving the CB[n]-forming reaction of formaldehyde. The longer oligomers (e. g. 15 and 16 ) bind to alkylammonium ions in water ≈100-fold weaker than macrocyclic CB[n] highlighting the high preorganization of the acyclic but polycyclic framework. We prepared a wide variety of acyclic CB[n] compounds (wall variants, solubilizing group variants, linker variants) based on glycoluril trimer and tetramer. In particular, 26 and 27 have been shown to possess a wide variety of chemically and biologically interesting functions. For example, 26 was used to formulate the insoluble drug Albendazole and treat mice bearing SK-OV-3 xenograft tumors. Compound 27 binds tightly to the neuromuscular blocking agents rocuronium, vecuronium, and cisatracurium and acts as an in vivo reversal agent for these compounds in anesthetized rats. Container 27 was also found to modulate the hyperlocomotive effect of rats that had been treated with methamphetamine. Finally, 38 has been used as a cross reactive component of sensor arrays that are capable of classifying and quantifying cancer related nitroamine and a range of over the counter drugs. Overall, the work demonstrates that acyclic CB[n]-type compounds are nicely pre-organized and therefore retain the essential aspects of the recognition properties of macrocyclic CB[n] but allow for more straightforward tailoring of structure and solubility that enables a variety of chemically and biologically important applications. 相似文献
73.
Sharad Babu Pillai Shweta D. Dabhi Prafulla K. Jha 《International Journal of Hydrogen Energy》2018,43(47):21649-21654
We present a systematic ab initio study of atomic hydrogen and oxygen adsorption on bismuthene monolayer and its alloys with arsenic and antimony through electronic structure calculations based on density functional theory within generalized gradient approximation. We systematically investigated the preferable adsorption site for hydrogen and oxygen atom on 2D Bi, BiAs and BiSb. It was found that the hydrogen atom prefers top site of bismuth atom and oxygen atom prefers to reside in the hexagonal ring of these 2D bismuth alloys. The free energy calculated from the individual adsorption energy for each monolayer subsequently guides us to predict the best suitable catalyst among the considered 2D monolayers. The 2D BiSb serves better for hydrogen evolution reaction (HER) with hydrogen adsorption energy as ?1.384 eV while 2D BiAs is suitable for oxygen evolution reaction (OER) with oxygen adsorption energy as ?1.092 eV. We further investigated the effects of the adsorbate atom on the electronic properties of 2D Bi, BiAs and BiSb. The adsorption of oxygen on 2D BiAs and BiSb was shown to reduce the bulk band gap by 40.56 and 67.79% respectively which will be advantageous for the observation of Quantum Spin Hall effect at ambient conditions. 相似文献
74.
Shweta J. Malode Nagaraj P. Shetti Sharanappa T. Nandibewoor 《Catalysis Letters》2011,141(10):1526-1540
Abstract
The kinetics of osmium(VIII) (Os(VIII)) and ruthenium(III) (Ru(III)) catalysed oxidation of l-valine (l-val) by diperiodatoargentate(III) (DPA) in aqueous alkaline medium at 25 °C and a constant ionic strength of 0.006 mol dm−3 was studied spectrophotometrically. The stoichiometry is the same in both the catalysed reactions, i.e., [l-val]:[DPA] = 1:1. The reaction is of first order in [Os(VIII)], [Ru(III)], and [DPA] and has less than unit order in [l-val] and negative fractional order in [OH−]. Added periodate had no effect on rate of reaction. The products were identified by spot test and characterized by spectral studies. The catalytic constant (K C) was also calculated for both catalysed reactions at different temperatures. The activation parameters with respect to slow step of the mechanisms were computed and discussed and thermodynamic quantities were also determined. It has been observed that the catalytic efficiency for the present reaction is in the order of Os(VIII) > Ru(III). The probable active species of catalyst and oxidant have been identified. 相似文献75.
Das KM Banerjee S Shekhar N Damodaran K Nair R Somani S Raiker VP Jain S Padmanabhan S 《International journal of molecular sciences》2011,12(3):2064-2076
Expression of human granulocyte macrophage colony stimulating factor (hGMCSF), a cytokine of therapeutic importance, as a thioredoxin (TRX) fusion has been investigated in Escherichia coli BL21 (DE3) codon plus cells. The expression of this protein was low when cloned under the T7 promoter without any fusion tags. High yield of GMCSF was achieved (~88 mg/L of fermentation broth) in the shake flask when the gene was fused to the E. coli TRX gene. The protein was purified using a single step Ni(2+)-NTA affinity chromatography and the column bound fusion tag was removed by on-column cleavage with enterokinase. The recombinant hGMCSF was expressed as a soluble and biologically active protein in E. coli, and upon purification, the final yield was ~44 mg/L in shake flask with a specific activity of 2.3 × 10(8) U/mg. The results of Western blot and RP-HPLC analyses, along with biological activity using the TF-1 cell line, established the identity of the purified hGMCSF. In this paper, we report the highest yield of hGMCSF expressed in E. coli. The bioreactor study shows that the yield of hGMCSF could be easily scalable with a yield of ~400 mg/L, opening up new opportunities for large scale production hGMCSF in E. coli. 相似文献
76.
The objective of the present work is to establish a convolutional type (Gurtin in Arch. Rat. Mech. Anal. 16:34?C50, 1964) variational theorem and a reciprocity theorem for the linear theory of generalized thermoelastic diffusion for homogeneous and isotropic elastic solids. 相似文献
77.
Taoufiq GueddarVivek Dua 《Computers & Chemical Engineering》2011,35(9):1838-1856
In this paper, reduced nonlinear refinery models are developed by generating and using input-output data from a process simulator. In particular, rigorous process models of continuous catalytic reformer (CCR) and naphtha splitter units are used for generating the data. To deal with complexity associated with large amounts of data, that is usually available in the refineries, a disaggregation-aggregation based approach is presented. The data is split (disaggregation) into smaller subsets and reduced artificial neural network (ANN) models are obtained for each of the subset. These ANN models are then combined (aggregation) to obtain an ANN model which represents all the data originally generated. The disaggregation step can be carried out within a parallel computing platform. Refinery optimization studies are carried out to demonstrate the applicability and the usefulness of the proposed model reduction approach. 相似文献
78.
A. Sozza C. Dua A. Kerlain C. Brylinski E. Zanoni 《Microelectronics Reliability》2004,44(7):6939-1113
The stability of metal layers on semiconductors is a key issue for the device electrical performances. Therefore, the reliability of SiC/Ti/Pt/Au system was investigated using storage steady-stress testing, AES (Auger Electron Spectrometry), and SIMS (Secondary Ions Mass Spectrometry) analysis. The study was conducted on different patterns for gate and interconnection structure to underline the different reliability problems. Auger and SIMS analysis showed important modifications in the three-metal structure without reactions with the SiC substrate. The resistance degradation was assigned to interdiffusion phenomena. It was analyzed with a diffusion-controlled model. Activation energies and mean time to failure (MTF) were calculated for a failure criterion defined as a 10% increase of the resistance. Finally, the different rules of the metallization degradation in MESFET behaviours for interconnections and gate were discussed. 相似文献
79.
The synthesis of analogues of the anti-tumour drug 2-[N-(hydroxymethyl)methylamino]-4,6-bis(dimethylamino)-1,3,5-triazine (HMPMM) in which the OH or a dimethylamino group is replaced by a carbohydrate has been explored. Triazinyl beta-glycosides were readily prepared by reaction of sugars with trimethyl-triazinylammonium salts. These were made with one or two methylamino groups on the triazine for reaction with formaldehyde to give the cytotoxic NMeCH2OH group. However, reaction of the triazinyl glycosides with formaldehyde gave complex intractable mixtures. When the carbohydrate portion was changed to the fully protected 2,3,4,6-tetra-O-acetyl glucose a good yield of the 2-[N-(hydroxymethyl)methylamino]-4-(dimethylamino)-1,3,5-triazin-2 -yl tetra-O-acetyl beta-glucoside was obtained. However, de-acetylation using sodium methoxide also removed the N-CH2OH group. We are investigating protection of the base-sensitive N-CH2OH group as trialkylsilyl and benzyl ethers and are looking at de-acetylation methods that are more selective. We have prepared glycosides in which the sugar is joined through the oxygen of the NMeCH2OH group. Coupling of acetobromoglucose with HMPMM catalysed by silver salts was not successful. Although methyl and cyclohexyl derivatives of HMPMM may be produced in high yields by reaction of HMPMM with methyl and cyclohexyl alcohols under acidic catalysis, production of glycosides in this way gave poor yields. MNDO calculations on reactions of HMPMM helped us devise improved reaction conditions for the condensation of 2,3,4,6-tetra-O-acetyl glucose with HMPMM and its derivatives. The best procedure to generate one of the target glycosides is to react 2,3,4,6-tetra-O-acetyl glucose and formaldehyde with 2-methylamino-4,6-bis(dimethylamino)-1,3,5-triazine. The beta-glycoside product was de-acetylated using potassium carbonate in dry methanol. 相似文献
80.
Innate defence of the eye by antimicrobial defensin peptides 总被引:1,自引:0,他引:1