Influence of pH on colour and iron content of peptide fractions obtained from bovine Hb concentrate hydrolysates

The effect of pH on colour and iron content (Fe) of peptide fractions obtained from bovine haemoglobin concentrate (BHC) hydrolysates was studied. Four hydrolysates were obtained using three enzymes: Protex‐6‐L (P), Fungal–Protease–Concetrate (FC) and Flavourzyme (F). BHC and its hydrolysates (P, FC, P + F, FC + F) were fractioned at pH 4.5, 7.0 and 9.5. Solubility and Fe from different fractions were measured. Correlations between CIELAB colour parameters and Fe from different fractions were analysed. The colour from different fractions varied from red to yellow (a* and b* positives). Lightness values (L*) ranged from twenty‐four to seventy. FC4.5 and FC + F4.5 fractions were the clearest and yellow (higher L*, b*, h), while BHC9.5 and P + F9.5 fractions had the lowest values of L*, b* and h. There was an inverse linear relationship between b* and L* parameters and Fe from fractions. This relationship could be associated with the pH of extraction. As pH increases Fe significantly increases and lower b* and L* values were obtained.     

Future publication success in science is better predicted by traditional measures than by the <Emphasis Type="Italic">h</Emphasis> index

Although the use of bibliometric indicators for evaluations in science is becoming more and more ubiquitous, little is known about how future publication success can be predicted from past publication success. Here, we investigated how the post-2000 publication success of 85 researchers in oncology could be predicted from their previous publication record. Our main findings are: (i) Rates of past achievement were better predictors than measures of cumulative achievement. (ii) A combination of authors’ past productivity and the past citation rate of their average paper was most successful in predicting future publication success (R ² ≈ 0.60). (iii) This combination of traditional bibliographic indicators clearly outperformed predictions based on the rate of the h index (R ² between 0.37 and 0.52). We discuss implications of our findings for views on creativity and for science evaluation.     

Decidability of Equivalence of Symbolic Derivations

We give in this paper an alternative, and we believe simpler, proof of a deep result by Mathieu Baudet, namely that the equivalence of symbolic constraints is decidable for deduction systems on a finite signature modulo a subterm convergent equational theory.     

Chrysin,Apigenin and Acacetin Inhibit Tumor Necrosis Factor-Related Apoptosis—Inducing Ligand Receptor-1 (TRAIL-R1) on Activated RAW264.7 Macrophages

Expression level of Tumor Necrosis Factor—related apoptosis—inducing ligand (TRAIL) receptors is one of the most important factors of TRAIL-mediated apoptosis in cancer cells. We here report for the first time data concerning TRAIL-R1 and TRAIL-R2 receptor expression on RAW264.7 macrophages. Three substances belonging to flavones: chrysin, apigenin and acacetin which differ from their substituents at the 4'' position in the phenyl ring were used in assays because of the variety of biological activities (e.g., anticancer activity) of the polyphenol compounds. The expression of TRAIL-R1 and TRAIL-R2 death receptors on non-stimulated and LPS (lipopolysaccharide)-stimulated macrophages was determined using flow cytometry. We demonstrate that RAW264.7 macrophages exhibit TRAIL-R1 surface expression and that the tested compounds: chrysin, apigenin and acacetin can inhibit TRAIL-R1 death receptor expression level on macrophages.     

Micro- and nanostructured Al2O3 surfaces for controlled vascular endothelial and smooth muscle cell adhesion and proliferation

The effect of the micro- and nanotopography on vascular cell-surface interaction is investigated using nano- and microstructured Al₂O₃ as model substrate. Two different nanostructured Al₂O₃ surfaces composed of low density (LD) and high density (HD) nanowires (NWs) were synthesized by chemical vapour deposition (CVD) and commercially available microstructured Al₂O₃ plates were used for comparison. A clear diverging response of human umbilical vein endothelial cells (HUVEC) and human umbilical vein smooth muscle cells (HUVSMC) was observed on these nano- and microstructured surfaces. LD Al₂O₃ NWs seem to enhance the proliferation of HUVECs selectively. This selective control of the cell-surface interaction by topography may represent a key issue for the future stent material design.     

Methodology of materials discovery in complex metal hydrides using experimental and computational tools

We present a review of the experimental and theoretical methods used in the discovery of new metal–hydrogen materials systems for hydrogen storage applications. Rather than a comprehensive review of all new materials and methods used in the metal hydride community, we focus on a specific subset of successful methods utilizing theoretical crystal structure prediction methods, computational approaches for screening large numbers of compound classes, and medium-throughput experimental methods for the preparation of such materials. Monte Carlo techniques paired with a simplified empirical Hamiltonian provide crystal structure candidates that are refined using density functional theory. First-principle methods using high-quality structural candidates are further screened for an estimate of reaction energetics, decomposition enthalpies, and determination of reaction pathways. Experimental synthesis utilizes a compacted-pellet sintering technique under high-pressure hydrogen at elevated temperatures. Crystal structure determination follows from a combination of Rietveld refinements of diffraction patterns and first-principles computation of total energies and dynamical stability of competing structures. The methods presented within are general and applicable to a wide class of materials for energy storage.     

Influence of Growth Rate on Eutectic Spacing,Microhardness, and Ultimate Tensile Strength in the Directionally Solidified Al-Cu-Ni Eutectic Alloy

Metallurgical and Materials Transactions B - In this work, the mechanical properties of the Al-Cu-Ni eutectic alloy, Al-32.5&nbsp;wt pct Cu-1&nbsp;wt pct Ni, were investigated in terms of...     

Spectrally selective and adaptive surfaces for protection against radiative heating: ITO and VO2

Two surface materials for reducing absorptivity of heat radiation from fires have been investigated. The first is VO₂, which is a thermochromic material. When the temperature of a VO₂ surface increases over a certain temperature, it switches, ideally, from infrared (IR)‐absorbing to IR‐reflecting. VO₂ window coatings are still on a research level, yet to be commercialized. In this study, VO₂ powder available on the market was investigated. The thermochromic effect could be identified but was not large enough to significantly improve the fire properties of treated surfaces. Some thoughts concerning how to improve the performance of VO₂ are discussed. The second investigated material is indium tin oxide (ITO), which is a so called low‐e coating, which means that it has low emissivity and absorptivity in the IR part of the spectrum. ITO is spectrally selective in the sense that it transmits visible light while reflecting a large fraction of the IR radiation, which is a rare property for surfaces in general but a typical property of thin electrically conducting non‐metallic films. It is shown that the application of ITO to poly(methyl methacrylate) (PMMA) significantly improves its fire properties. ITO coating is a mature technology already in widespread use today in the electronics industry. Copyright © 2012 John Wiley & Sons, Ltd.     

Performance Study of a Closed-Type Heat Pump Tumble Dryer Using a Simulation Model and an Experimental Set-Up

In the interests of competitiveness, manufactures of tumble dryers are seeking to reduce both their electricity use and the drying time. This study examines how the cylinder volume of the compressor and the total heat transfer of the condenser influence the drying time and electricity use in a heat pump tumble dryer. A transient simulation model was developed and compared to an experimental set-up with good similarity. The simulations show that increasing the cylinder volume of the compressor by 50% decreases the drying time by 14% without using more electricity.